Article
Surgery
Shinji Onda, Koichiro Haruki, Kenei Furukawa, Jungo Yasuda, Yoshihiro Shirai, Taro Sakamoto, Takeshi Gocho, Toru Ikegami
Summary: LSVC technique is a safe and reliable method for the Pringle maneuver in repeat laparoscopic hepatectomy, as demonstrated by successful inflow control in 14 cases of patients.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2021)
Article
Oncology
Yi Zhou, Yifan Wang, Jinliang Ma, Chuanhai Zhang
Summary: This study introduces a new laparoscopic Pringle maneuver and investigates its application in laparoscopic hepatectomy. The hooking method for intermittent occlusion of hepatic inflow was used in all 17 patients, and it was found to be a simple, safe, and effective method without any major complications.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Gastroenterology & Hepatology
Alexander M. Fagenson, Elizabeth M. Gleeson, Fatima Nabi, Kwan N. Lau, Henry A. Pitt
Summary: The study found that patients undergoing partial hepatectomy or with metastatic disease had increased postoperative complications when a Pringle Maneuver was performed, along with a significant increase in operative time.
Review
Surgery
Shahd Mobarak, Martyn C. Stott, Munir Tarazi, Rebecca J. Varley, Madhav S. Dave, Minas Baltatzis, Thomas Satyadas
Summary: This study found that selective hepatic vascular exclusion during hepatic resection can significantly reduce mortality and complication rates, with no significant differences observed in hepatic vein rupture, post-operative hemorrhage, operative time, or length of hospital stay.
FRONTIERS IN SURGERY
(2022)
Article
Oncology
Yuichi Nakaseko, Koichiro Haruki, Keigo Nakashima, Kenei Furukawa, Yutaka Suzuki, Toru Ikegami
Summary: This study introduces a technique for hepatic inflow control using an endovascular clip. By confirming the space between the right and dorsal side of the hepatoduodenal ligament and introducing the clip, hepatic inflow can be controlled. The patients had successful postoperative recovery without any complications and were discharged. This technique may be safe and feasible for open and laparoscopic hepatectomy after esophagectomy.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Review
Surgery
Pan He, Kai He, Furui Zhong, Song Su, Cheng Fang, Shu Qin, Fangyi Pen, Xianming Xia, Bo Li
Summary: Infrahepatic inferior vena cava clamping combined with the Pringle maneuver during hepatectomies can effectively reduce intraoperative bleeding, blood transfusion rates, and postoperative complications, while adding minimal time to the operation.
ASIAN JOURNAL OF SURGERY
(2021)
Article
Gastroenterology & Hepatology
Shi-Chuan Tang, Yong-Kang Diao, Kong-Ying Lin, Chao Li, Xiao Xu, Lei Liang, Jie Kong, Qing-Jing Chen, Xian-Ming Wang, Fu-Bao Liu, Wei-Min Gu, Ya-Hao Zhou, Ying-Jian Liang, Hong-Zhi Liu, Ming-Da Wang, Lan-Qing Yao, Timothy M. Pawlik, Feng Shen, Wan Yee Lau, Tian Yang, Yong-Yi Zeng
Summary: The use of Pringle maneuver (PM) during hepatectomy can reduce intraoperative bleeding and the need for perioperative transfusion. However, its effect on long-term recurrence and survival for patients with hepatocellular carcinoma (HCC) remains controversial. This study found that not using PM can lower the risk of postoperative recurrence and cancer-specific death for HCC patients.
HEPATOBILIARY SURGERY AND NUTRITION
(2023)
Article
Oncology
Jianwei Liu, Wei Wang, Chunchao Shi, Chenqi Li, Feng Xue, Lei Hu, Yi Wang, Ruiliang Ge
Summary: In patients with hepatocellular carcinoma undergoing complex hepatectomy, prolonged continuous Pringle maneuver (CPM) was found to be more beneficial than prolonged intermittent Pringle maneuver (IPM) in terms of shorter operation time, reduced intraoperative bleeding and transfusion, lower postoperative complications and liver function injury, without affecting overall survival or tumor recurrence.
Review
Oncology
Lingbo Hu, Aidong Wang, Yingli Qiao, Xiandan Huang
Summary: Intermittent Pringle maneuver (IPM) is effective in controlling blood loss during liver resection and does not affect the long-term survival of patients with hepatocellular carcinoma (HCC).
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, General & Internal
Tom Darius, Martial Vergauwen, Louis Maistriaux, Robin Evrard, Andrea Schlegel, Matteo Mueller, Donna O'Neil, Andrew Southam, Selda Aydin, Arnaud Devresse, Martine De Meyer, Pierre Gianello, Christian Ludwig, Philipp Dutkowski, Michel Mourad
Summary: Short bubble and subsequent intermittent surface oxygenation is an effective and cheap preservation strategy during hypothermic machine perfusion (HMP), which can protect mitochondria and eliminate the need/costs of a membrane oxygenator and oxygen source during transport.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Anesthesiology
Mai Yamamoto, Shunichi Takagi, Miho Kijima, Hanae Sato, Akira Doshu-Kajiura, Osamu Kitajima, Takahiro Suzuki
Summary: The study aimed to investigate the impact of the Pringle maneuver on the duration and intensity of rocuronium-induced neuromuscular block, as well as the changes in plasma concentration of rocuronium. The results showed that the Pringle maneuver significantly prolonged the duration of action of rocuronium and decreased the muscle contraction, but did not affect the plasma concentration of rocuronium.
JOURNAL OF ANESTHESIA
(2023)
Editorial Material
Oncology
Pierre de Mathelin, Caterina Cusumano, Philippe Bachellier, Maxime Foguenne, Pietro Addeo
Summary: Total vascular exclusion with veno-venous bypass and in-situ liver hypothermic perfusion is an effective method for managing venous obstruction at the hepatic veins-inferior vena cava confluence when liver resection is needed. It can reduce the risk of blood loss and postoperative liver failure.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Surgery
Koshiro Morino, Satoru Seo, Tomoaki Yoh, Rei Toda, Kenji Yoshino, Takahiro Nishio, Gen Yamamoto, Takamichi Ishii, Kojiro Taura, Etsuro Hatano
Summary: This study aimed to assess the impact of intermittent Pringle maneuver (PM) on post-hepatectomy liver failure (PHLF) and explore whether PM provides additional value for predicting PHLF. The results showed that PM was associated with the occurrence of PHLF, and intraoperative factors including PM may provide additional value to predict and intervene in PHLF.
WORLD JOURNAL OF SURGERY
(2023)
Article
Cardiac & Cardiovascular Systems
Niels Moeslund, Imran A. Ertugrul, Michiel A. Hu, Frederik Flyvholm Dalsgaard, Lars Bo Ilkjaer, Pia Ryhammer, Michael Pedersen, Michiel E. Erasmus, Hans Eiskjaer
Summary: In this study, a novel oxygenated hypothermic machine perfusion (HMP) system was compared to static cold storage (SCS) in heart transplantation (HTX). The results showed that hearts preserved with HMP exhibited increased biventricular contractility post-HTX and required less dobutamine for maintaining cardiac output. Additionally, HMP groups had lower levels of myocardial damage. Therefore, DCD HTX can be successfully performed using DPP followed by preservation with HMP.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2023)
Article
Surgery
Santiago A. Ortiz Galindo, Philipp K. Haber, Christian Benzing, Felix Krenzien, Anna Riddermann, Oliver Frisch, Wenzel Schoening, Moritz Schmelzle, Johann Pratschke, Linda Feldbruegge
Summary: The study aimed to analyze the impact of minimally invasive intermittent Pringle maneuver (IPM) on postoperative outcomes in patients with hepatocellular carcinoma (HCC) and liver cirrhosis. The findings suggest that the use of IPM in minimally invasive liver resection is safe and feasible for patients with HCC, including those with compensated liver cirrhosis, without increasing the risk of intraoperative blood transfusion or postoperative complications, and without affecting postoperative liver function tests for cirrhotic patients.
LANGENBECKS ARCHIVES OF SURGERY
(2022)
Article
Clinical Neurology
Dolors Pi Castro, Roberto Jose-Lopez, Francisco Fernandez Flores, Rosa M. Rabanal Prados, Maria Teresa Mandara, Carles Arus, Marti Pumarola Batlle
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
(2020)
Article
Biophysics
Yanisleydis Hernandez-Villegas, Sandra Ortega-Martorell, Carles Arus, Alfredo Vellido, Margarida Julia-Sape
Summary: Despite the success of automated pattern recognition methods in human brain tumor classification, there is limited attention on automated data quality assessment in neuro-oncology's MRS field. Automatic detection of MRS artifacts is beneficial for radiology, ensuring more reliable tumor characterizations and robust pattern recognition-based tumor classifiers. This study demonstrates the potential validity of using Convex Non-Negative Matrix Factorization for unsupervised detection of MRS signal sources and artifacts.
NMR IN BIOMEDICINE
(2022)
Article
Biophysics
Shuang Wu, Pilar Calero-Perez, Lucia Villamanan, Nuria Arias-Ramos, Marti Pumarola, Sandra Ortega-Martorell, Margarida Julia-Sape, Carles Arus, Ana Paula Candiota
NMR IN BIOMEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Laura Valls-Lacalle, Marta Consegal, Marisol Ruiz-Meana, Begona Benito, Javier Inserte, Ignasi Barba, Ignacio Ferreira-Gonzalez, Antonio Rodriguez-Sinovas
Article
Biochemistry & Molecular Biology
Claudia Beltran, Rosario Pardo, Diana Bou-Teen, Marisol Ruiz-Meana, Josep A. Villena, Ignacio Ferreira-Gonzalez, Ignasi Barba
Article
Multidisciplinary Sciences
Camila Lema, Mireia Andres, Santiago Aguade-Bruix, Marta Consegal, Antonio Rodriguez-Sinovas, Begona Benito, Ignacio Ferreira-Gonzalez, Ignasi Barba
SCIENTIFIC REPORTS
(2020)
Article
Cardiac & Cardiovascular Systems
Bruno Garcia del Blanco, Imanol Otaegui, Jose F. Rodriguez-Palomares, Antoni Bayes-Genis, Eduard Fernandez-Nofrerias, Victoria Vilalta del Olmo, Xavier Carrillo, Borja Ibanez, Fernando Worner, Juan Casanova, Eva Pueo, Jose R. Gonzalez-Juanatey, Javier Lopez-Pais, Alfredo Bardaji, Gil Bonet, Monica Fuertes, Antonio Rodriguez-Sinovas, Marisol Ruiz-Meana, Javier Inserte, Ignasi Barba, Sandra Gomez-Talavera, Gerard Marti, Bernat Serra, Neus Bellera, Manuel Ojeda-Ramos, Hug Cuellar, Filipa Valente, Maria Angeles Carmona, Elisabet Miro-Casas, Josep R. Marsal, Antonia Sambola, Rosa M. Lidon, Jordi Baneras, Jaime Elizaga, Ferran Padilla, Jose A. Barrabes, Derek J. Hausenloy, Ignacio Ferreira-Gonzalez, David Garcia-Dorado
Summary: In patients undergoing primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI), neither remote ischemic conditioning (RIC) nor the GLP-1 analog exenatide, alone or in combination, were able to reduce infarct size (IS).
BASIC RESEARCH IN CARDIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Shuang Wu, Pilar Calero-Perez, Caries Anus, Ana Paula Candiota
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2020)
Article
Biochemistry & Molecular Biology
Marta Consegal, Norberto Nunez, Ignasi Barba, Begona Benito, Marisol Ruiz-Meana, Javier Inserte, Ignacio Ferreira-Gonzalez, Antonio Rodriguez-Sinovas
Summary: The study showed that both succinate dehydrogenase (SDH) inhibition and remote ischemic perconditioning (RIC) can reduce myocardial infarction size, but they do not have an additive effect when used together. Furthermore, the concentrations of selected citric acid cycle metabolites in plasma were found to be influenced by protective maneuvers and correlated with irreversible injury.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Lucia Villamanan, Laura Martinez-Escardo, Carles Arus, Victor J. Yuste, Ana P. Candiota
Summary: In vitro experiments demonstrated that combined treatment may simultaneously release two potent immunogenic signals, potentially explaining its superior performance over single treatments in vivo.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biochemistry & Molecular Biology
Ivan J. Nunez-Gil, Mireia Andres, Begona Benito, Esther Bernardo, Oscar Vedia, Ignacio Ferreira-Gonzalez, Ignasi Barba
Summary: Takotsubo syndrome differs metabolically from AMI, demonstrating limited myocardial energy production capacity during the acute phase. Metabolic profiling can accurately distinguish between Takotsubo and acute myocardial infarction.
Article
Radiology, Nuclear Medicine & Medical Imaging
Francesco Grussu, Kinga Bernatowicz, Irene Casanova-Salas, Natalia Castro, Paolo Nuciforo, Joaquin Mateo, Ignasi Barba, Raquel Perez-Lopez
Summary: This study investigates the relationship between diffusion-weighted MRI signals and hepatocyte microstructure, and finds that important information about liver cell size and diffusivity can be obtained from minimal diffusion encodings under specific conditions.
MAGNETIC RESONANCE IN MEDICINE
(2022)
Correction
Chemistry, Multidisciplinary
Yajie Zhang, Miguel Garcia-Gabilondo, Alba Grayston, Irene V. J. Feiner, Irene Anton-Sales, Rodrigo A. Loiola, Jordi Llop, Pedro Ramos-Cabrer, Ignasi Barba, David Garcia-Dorado, Fabien Gosselet, Anna Rosell, Anna Roig
Summary: The study successfully prepared PLGA protein nanocarriers with tailor-made fluorescence/MRI/PET imaging modalities and explored their potential applications in the biomedical field.
Article
Multidisciplinary Sciences
Luis Miguel Nunez, Enrique Romero, Margarida Julia-Sape, Maria Jesus Ledesma-Carbayo, Andres Santos, Carles Arus, Ana Paula Candiota, Alfredo Vellido
SCIENTIFIC REPORTS
(2020)
Article
Chemistry, Multidisciplinary
Yajie Zhang, Miguel Garcia-Gabilondo, Alba Grayston, Irene V. J. Feiner, Irene Anton-Sales, Rodrigo A. Loiola, Jordi Llop, Pedro Ramos-Cabrer, Ignasi Barba, David Garcia-Dorado, Fabien Gosselet, Anna Rosell, Anna Roig