Heterogeneity across the murine small and large intestine

Studies of mucus in mouse stomach, small intestine, and colon. III. Gastrointestinal Muc5ac and Muc2 mucin O-glycan patterns reveal a regiospecific distribution

(2013) Jessica M. Holmén Larsson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice

(2013) Purna C. Kashyap et al.   GASTROENTEROLOGY

Induced and Natural Regulatory T Cells in the Development of Inflammatory Bowel Disease

(2013) Christopher G. Mayne et al.   INFLAMMATORY BOWEL DISEASES

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells

(2013) Steven A. Saenz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Role of the Gut Microbiota in the Development and Function of Lymphoid Cells

(2013) N. Kamada et al.   JOURNAL OF IMMUNOLOGY

REG3γ-deficient mice have altered mucus distribution and increased mucosal inflammatory responses to the microbiota and enteric pathogens in the ileum

(2013) L MP Loonen et al.   Mucosal Immunology

Microbiota restricts trafficking of bacteria to mesenteric lymph nodes by CX3CR1hi cells

(2013) Gretchen E. Diehl et al.   NATURE

Bacterial colonization factors control specificity and stability of the gut microbiota

(2013) S. Melanie Lee et al.   NATURE

Control of pathogens and pathobionts by the gut microbiota

(2013) Nobuhiko Kamada et al.   NATURE IMMUNOLOGY

Commensal bacteria at the interface of host metabolism and the immune system

(2013) Jonathan R Brestoff et al.   NATURE IMMUNOLOGY

The role of the immune system in governing host-microbe interactions in the intestine

(2013) Eric M Brown et al.   NATURE IMMUNOLOGY

The gut microbiota — masters of host development and physiology

(2013) Felix Sommer et al.   NATURE REVIEWS MICROBIOLOGY

Probiotics Can Generate FoxP3 T-Cell Responses in the Small Intestine and Simultaneously Inducing CD4 and CD8 T Cell Activation in the Large Intestine

(2013) Maaike J. Smelt et al.   PLoS One

Intestinal Intraepithelial Lymphocyte-Enterocyte Crosstalk Regulates Production of Bactericidal Angiogenin 4 by Paneth Cells upon Microbial Challenge

(2013) Catherine R. Walker et al.   PLoS One

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

(2013) P. C. Kashyap et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mucus Enhances Gut Homeostasis and Oral Tolerance by Delivering Immunoregulatory Signals

(2013) M. Shan et al.   SCIENCE

GPR15-Mediated Homing Controls Immune Homeostasis in the Large Intestine Mucosa

(2013) S. V. Kim et al.   SCIENCE

The Long-Term Stability of the Human Gut Microbiota

(2013) J. J. Faith et al.   SCIENCE

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

Host and Microbial Factors in Regulation of T Cells in the Intestine

(2013) Chang H. Kim   Frontiers in Immunology

CD64 distinguishes macrophages from dendritic cells in the gut and reveals the Th1-inducing role of mesenteric lymph node macrophages during colitis

(2012) Samira Tamoutounour et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Extracellular cathepsin K exerts antimicrobial activity and is protective against chronic intestinal inflammation in mice

(2012) Christian Sina et al.   GUT

Innate Lymphoid Cell Interactions with Microbiota: Implications for Intestinal Health and Disease

(2012) Gregory F. Sonnenberg et al.   IMMUNITY

IgA production in the large intestine is modulated by a different mechanism than in the small intestine: Bacteroides acidifaciens promotes IgA production in the large intestine by inducing germinal center formation and increasing the number of IgA+ B cells

(2012) Tsutomu Yanagibashi et al.   IMMUNOBIOLOGY

The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

(2012) Erwin G Zoetendal et al.   ISME Journal

Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice

(2012) Junjie Mei et al.   JOURNAL OF CLINICAL INVESTIGATION

Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13

(2012) Ana Camelo et al.   JOURNAL OF GASTROENTEROLOGY

Myenteric neurons of the mouse small intestine undergo significant electrophysiological and morphological changes during postnatal development

(2012) Jaime Pei Pei Foong et al.   JOURNAL OF PHYSIOLOGY-LONDON

Temporal and spatial interplay of microbiota and intestinal mucosa drive establishment of immune homeostasis in conventionalized mice

(2012) Sahar El Aidy et al.   Mucosal Immunology

Resident and pro-inflammatory macrophages in the colon represent alternative context-dependent fates of the same Ly6Chi monocyte precursors

(2012) C C Bain et al.   Mucosal Immunology

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Increased Intratumoral Neutrophil in Colorectal Carcinomas Correlates Closely with Malignant Phenotype and Predicts Patients' Adverse Prognosis

(2012) Hui-Lan Rao et al.   PLoS One

Patterns of Early Gut Colonization Shape Future Immune Responses of the Host

(2012) Camilla Hartmann Friis Hansen et al.   PLoS One

Mucin Muc2 Deficiency and Weaning Influences the Expression of the Innate Defense Genes Reg3β, Reg3γ and Angiogenin-4

(2012) Nanda Burger-van Paassen et al.   PLoS One

The Goblet Cell Is the Cellular Source of the Anti-Microbial Angiogenin 4 in the Large Intestine Post Trichuris muris Infection

(2012) Ruth A. Forman et al.   PLoS One

Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines

(2012) M. R. Hepworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neutrophils cast extracellular traps in response to protozoan parasites

(2012) Delbert S. Abi Abdallah et al.   Frontiers in Immunology

Intestinal antimicrobial peptides during homeostasis, infection, and disease

(2012) Luciana R. Muniz et al.   Frontiers in Immunology

Role of mucus layers in gut infection and inflammation

(2011) Gunnar C Hansson   CURRENT OPINION IN MICROBIOLOGY

Intestinal Dendritic Cells Specialize to Activate Transforming Growth Factor-β and Induce Foxp3+ Regulatory T Cells via Integrin αvβ8

(2011) John J. Worthington et al.   GASTROENTEROLOGY

Cathelicidin Signaling via the Toll-like Receptor Protects Against Colitis in Mice

(2011) Hon Wai Koon et al.   GASTROENTEROLOGY

CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation, and colitogenic Th17 responses in mice

(2011) Oscar Medina-Contreras et al.   JOURNAL OF CLINICAL INVESTIGATION

Muc5ac: a critical component mediating the rejection of enteric nematodes

(2011) Sumaira Z. Hasnain et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Pan-B Cell Marker CD22 Is Expressed on Gastrointestinal Eosinophils and Negatively Regulates Tissue Eosinophilia

(2011) T. Wen et al.   JOURNAL OF IMMUNOLOGY

Functional Specializations of Intestinal Dendritic Cell and Macrophage Subsets That Control Th17 and Regulatory T Cell Responses Are Dependent on the T Cell/APC Ratio, Source of Mouse Strain, and Regional Localization

(2011) T. L. Denning et al.   JOURNAL OF IMMUNOLOGY

Eosinophils Regulate Dendritic Cells and Th2 Pulmonary Immune Responses following Allergen Provocation

(2011) E. A. Jacobsen et al.   JOURNAL OF IMMUNOLOGY

Immunobiology of Intestinal Eosinophils – A Dogma in the Changing?

(2011) Marcus Svensson-Frej   Journal of Innate Immunity

Role of Eosinophils in Inflammatory Bowel and Gastrointestinal Diseases

(2011) Samantha A Woodruff et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Eosinophils are required for the maintenance of plasma cells in the bone marrow

(2011) Van Trung Chu et al.   NATURE IMMUNOLOGY

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Mucin dynamics and enteric pathogens

(2011) Michael A. McGuckin et al.   NATURE REVIEWS MICROBIOLOGY

Arginase-1-expressing macrophages are dispensable for resistance to infection with the gastrointestinal helminth Trichuris muris

(2011) R. BOWCUTT et al.   PARASITE IMMUNOLOGY

Restricting Microbial Exposure in Early Life Negates the Immune Benefits Associated with Gut Colonization in Environments of High Microbial Diversity

(2011) Imke E. Mulder et al.   PLoS One

The Antibacterial Lectin RegIII  Promotes the Spatial Segregation of Microbiota and Host in the Intestine

(2011) S. Vaishnava et al.   SCIENCE

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

The intestinal epithelial barrier in the control of homeostasis and immunity

(2011) Maria Rescigno   TRENDS IN IMMUNOLOGY

Mechanisms underlying the localisation of mast cells in tissues

(2011) Sarah J. Collington et al.   TRENDS IN IMMUNOLOGY

Microbial adhesins to gastrointestinal mucus

(2011) Nathalie Juge   TRENDS IN MICROBIOLOGY

The Starting Lineup: Key Microbial Players in Intestinal Immunity and Homeostasis

(2011) Nicola C. Reading et al.   Frontiers in Microbiology

Gut-associated lymphoid tissue, T cell trafficking, and chronic intestinal inflammation

(2010) Iurii Koboziev et al.   Annals of the New York Academy of Sciences

Interactions Between Gut Microbiota and Host Metabolism Predisposing to Obesity and Diabetes

(2010) Giovanni Musso et al.   Annual Review of Medicine

Microbiota–immune system interaction: an uneasy alliance

(2010) Nita H Salzman   CURRENT OPINION IN MICROBIOLOGY

High temporal and inter-individual variation detected in the human ileal microbiota

(2010) Carien C. G. M. Booijink et al.   ENVIRONMENTAL MICROBIOLOGY

The puzzle of intestinal lamina propria dendritic cells and macrophages

(2010) Oliver Pabst et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mast cells in allergy and infection: Versatile effector and regulatory cells in innate and adaptive immunity

(2010) Stephen J. Galli et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mucin Gene Deficiency in Mice Impairs Host Resistance to an Enteric Parasitic Infection

(2010) Sumaira Z. Hasnain et al.   GASTROENTEROLOGY

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

(2010) E F Murphy et al.   GUT

Regulated Expression of Nuclear Receptor RORγt Confers Distinct Functional Fates to NK Cell Receptor-Expressing RORγt+ Innate Lymphocytes

(2010) Cedric Vonarbourg et al.   IMMUNITY

The diverse ontogeny and function of murine small intestinal dendritic cell/macrophage subsets

(2010) Emma K. Persson et al.   IMMUNOBIOLOGY

Spatial organization of intestinal microbiota in the mouse ascending colon

(2010) Gerardo M Nava et al.   ISME Journal

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Gastrointestinal eosinophils in health, disease and functional disorders

(2010) Nicholas Powell et al.   Nature Reviews Gastroenterology & Hepatology

Accumulation of eosinophils in intestine-draining mesenteric lymph nodes occurs after Trichuris muris infection

(2010) M. SVENSSON et al.   PARASITE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5

(2010) M. Vijay-Kumar et al.   SCIENCE

Innate immune cell populations function as initiators and effectors in Th2 cytokine responses

(2010) Steven A. Saenz et al.   TRENDS IN IMMUNOLOGY

Muc2 Protects against Lethal Infectious Colitis by Disassociating Pathogenic and Commensal Bacteria from the Colonic Mucosa

(2010) Kirk S. B. Bergstrom et al.   PLoS Pathogens

Paneth Cell Development, Differentiation, and Function: New Molecular Cues

(2009) Thaddeus S. Stappenbeck   GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

The Key Role of Segmented Filamentous Bacteria in the Coordinated Maturation of Gut Helper T Cell Responses

(2009) Valérie Gaboriau-Routhiau et al.   IMMUNITY

Differences in Intraepithelial Lymphocytes in the Proximal, Middle, Distal Parts of Small Intestine, Cecum, and Colon of Mice

(2009) Hodaka Suzuki   IMMUNOLOGICAL INVESTIGATIONS

CD4+T-cell localization to the large intestinal mucosa duringTrichuris murisinfection is mediated by Gαi-coupled receptors but is CCR6- and CXCR3-independent

(2009) Marcus Svensson et al.   IMMUNOLOGY

Generation of gut-homing T cells and their localization to the small intestinal mucosa

(2009) William Agace   IMMUNOLOGY LETTERS

Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions

(2009) Olga Schulz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Disruption of Th2 Immunity Results in a Gender-Specific Expansion of IL-13 Producing Accessory NK Cells during Helminth Infection

(2009) M. R. Hepworth et al.   JOURNAL OF IMMUNOLOGY

Basophils Can Directly Present or Cross-Present Antigen to CD8 Lymphocytes and Alter CD8 T Cell Differentiation into IL-10-Producing Phenotypes

(2009) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Rapid Dendritic Cell Mobilization to the Large Intestinal Epithelium Is Associated with Resistance to Trichuris muris Infection

(2009) S. M. Cruickshank et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3

(2009) S. Kim et al.   JOURNAL OF IMMUNOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

MHC class II–dependent basophil–CD4+ T cell interactions promote TH2 cytokine–dependent immunity

(2009) Jacqueline G Perrigoue et al.   NATURE IMMUNOLOGY

Enteric defensins are essential regulators of intestinal microbial ecology

(2009) Nita H Salzman et al.   NATURE IMMUNOLOGY

Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism

(2009) Katherine R. Groschwitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intestinal T cells: Facing the mucosal immune dilemma with synergy and diversity

(2009) Femke van Wijk et al.   SEMINARS IN IMMUNOLOGY

Basophil effector function and homeostasis during helminth infection

(2008) C. Ohnmacht et al.   BLOOD

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Secreted enteric antimicrobial activity localises to the mucus surface layer

(2008) U Meyer-Hoffert et al.   GUT

Gr1+ Inflammatory Monocytes Are Required for Mucosal Resistance to the Pathogen Toxoplasma gondii

(2008) Ildiko R. Dunay et al.   IMMUNITY

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent stepin ΔinvG S. Typhimurium colitis

(2008) Siegfried Hapfelmeier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Small intestinal CD103+dendritic cells display unique functional properties that are conserved between mice and humans

(2008) Elin Jaensson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Developmental switch of intestinal antimicrobial peptide expression

(2008) Sandrine Ménard et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The intestinal epithelium: sensors to effectors in nematode infection

(2008) D Artis et al.   Mucosal Immunology

ATP drives lamina propria TH17 cell differentiation

(2008) Koji Atarashi et al.   NATURE

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA