Inflammatory pathways in the early steps of colorectal cancer development

The Mechanisms of Chansu in Inducing Efficient Apoptosis in Colon Cancer Cells

(2013) Chun Li et al.   Evidence-based Complementary and Alternative Medicine

Insulin mediated DNA damage in mammalian colon cells and human lymphocytes in vitro

(2013) Eman Maher Othman et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

IL-22-producing neutrophils contribute to antimicrobial defense and restitution of colonic epithelial integrity during colitis

(2013) C. L. Zindl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Impact of Matrix Metalloproteinases and Their Tissue Inhibitors in Inflammatory Bowel Diseases

(2012) Gábor Lakatos et al.   DIGESTIVE DISEASES

The transcription factor NF-E2-related Factor 2 (Nrf2): a protooncogene?

(2012) Phillip Shelton et al.   FASEB JOURNAL

Propofol induces proliferation and invasion of gallbladder cancer cells through activation of Nrf2

(2012) Lingmin Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Colonic Epithelial Cells Express Specific Ligands for Mucosal Macrophage Immunosuppressive Receptors Siglec-7 and -9

(2012) K. Miyazaki et al.   JOURNAL OF IMMUNOLOGY

Nrf2 knockout enhances intestinal tumorigenesis inApcmin/+mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation

(2012) Ka Lung Cheung et al.   MOLECULAR CARCINOGENESIS

IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine

(2012) Samuel Huber et al.   NATURE

Clinical significance of mitochondrial transcription factor A expression in patients with colorectal cancer

(2012) Yoshifumi Nakayama   ONCOLOGY REPORTS

The Functional Interaction between Acyl-CoA Synthetase 4, 5-Lipooxygenase and Cyclooxygenase-2 Controls Tumor Growth: A Novel Therapeutic Target

(2012) Ulises D. Orlando et al.   PLoS One

Innate IL-17 and IL-22 responses to enteric bacterial pathogens

(2012) Stephen J. Rubino et al.   TRENDS IN IMMUNOLOGY

Mitochondrial Genome Instability and ROS Enhance Intestinal Tumorigenesis in APCMin/+ Mice

(2011) Dong Kyun Woo et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanistic Contribution of Ubiquitous 15-Lipoxygenase-1 Expression Loss in Cancer Cells to Terminal Cell Differentiation Evasion

(2011) M. J. Moussalli et al.   Cancer Prevention Research

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Beginnings of a Good Apoptotic Meal: The Find-Me and Eat-Me Signaling Pathways

(2011) Kodi S. Ravichandran   IMMUNITY

SIRT3 Is a Mitochondria-Localized Tumor Suppressor Required for Maintenance of Mitochondrial Integrity and Metabolism during Stress

(2010) Hyun-Seok Kim et al.   CANCER CELL

Altered Expression of Apoptosis Biomarkers in Human Colorectal Microadenomas

(2010) P. Sena et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Resveratrol Suppresses Colitis and Colon Cancer Associated with Colitis

(2010) X. Cui et al.   Cancer Prevention Research

Calorie Restriction Reduces Oxidative Stress by SIRT3-Mediated SOD2 Activation

(2010) Xiaolei Qiu et al.   Cell Metabolism

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Oxidative stress promotes myofibroblast differentiation and tumour spreading

(2010) Aurore Toullec et al.   EMBO Molecular Medicine

Oxidative stress, inflammation, and cancer: How are they linked?

(2010) Simone Reuter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive species and DNA damage in chronic inflammation: reconciling chemical mechanisms and biological fates

(2010) Pallavi Lonkar et al.   INTERNATIONAL JOURNAL OF CANCER

Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis

(2010) Michał P. Wasilewicz et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Chronic inflammation and mutagenesis

(2010) Lynnette R. Ferguson   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1

(2010) Masaaki Komatsu et al.   NATURE CELL BIOLOGY

Functional Interaction between Acyl-CoA Synthetase 4, Lipooxygenases and Cyclooxygenase-2 in the Aggressive Phenotype of Breast Cancer Cells

(2010) Paula M. Maloberti et al.   PLoS One

SIRT1 regulates Dishevelled proteins and promotes transient and constitutive Wnt signaling

(2010) K. R. Holloway et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Macrophages: Master Regulators of Inflammation and Fibrosis

(2010) Thomas Wynn et al.   SEMINARS IN LIVER DISEASE

15-Epi-lipoxin A4Inhibits Myeloperoxidase Signaling and Enhances Resolution of Acute Lung Injury

(2009) Driss El Kebir et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Anti- and pro-tumor functions of autophagy

(2009) Eugenia Morselli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

SIRT1-dependent regulation of chromatin and transcription: Linking NAD+ metabolism and signaling to the control of cellular functions

(2009) Tong Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cyclooxygenase-2 and Hypoxia-Inducible Factor-1α protein expression is related to inflammation, and up-regulated since the early steps of colorectal carcinogenesis

(2009) Francesco Mariani et al.   CANCER LETTERS

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

SirT1 Is an Inhibitor of Proliferation and Tumor Formation in Colon Cancer

(2009) Neha Kabra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

(2009) G. Solinas et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Resveratrol (Trans-3,5,4'-trihydroxystilbene) Induces Silent Mating Type Information Regulation-1 and Down-Regulates Nuclear Transcription Factor- B Activation to Abrogate Dextran Sulfate Sodium-Induced Colitis

(2009) U. P. Singh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer

(2009) Brittney Jung-Hynes et al.   JOURNAL OF PINEAL RESEARCH

SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer

(2009) Katsuhiko Nosho et al.   MODERN PATHOLOGY

Origin and function of tumor stroma fibroblasts

(2009) Georgia Xouri et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The regulation of aging: does autophagy underlie longevity?

(2009) Tibor Vellai et al.   TRENDS IN CELL BIOLOGY

Imbalance of tissue inhibitors of metalloproteinases (TIMP) – 1 and – 4 serum levels, in patients with inflammatory bowel disease

(2008) Andreas N Kapsoritakis et al.   BMC GASTROENTEROLOGY

Myeloperoxidase-Positive Cell Infiltration in Colorectal Carcinogenesis as Indicator of Colorectal Cancer Risk

(2008) L. Roncucci et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The role of hypoxia-inducible factors in tumorigenesis

(2008) E B Rankin et al.   CELL DEATH AND DIFFERENTIATION

Overexpression of 5-Lipoxygenase in Colon Polyps and Cancer and the Effect of 5-LOX Inhibitors In vitro and in a Murine Model

(2008) L. G. Melstrom et al.   CLINICAL CANCER RESEARCH

DNA Hypermethylation Contributes to Incomplete Synthesis of Carbohydrate Determinants in Gastrointestinal Cancer

(2008) Yuki I. Kawamura et al.   GASTROENTEROLOGY

DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

(2008) Lisiane B. Meira et al.   JOURNAL OF CLINICAL INVESTIGATION

Relevance of granulocyte apoptosis to resolution of inflammation at the respiratory mucosa

(2008) A E Leitch et al.   Mucosal Immunology

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

(2008) Ron Firestein et al.   PLoS One