Adipokines and proinflammatory cytokines, the key mediators in the pathogenesis of nonalcoholic fatty liver disease

Adiponectin: A multitasking player in the field of liver diseases

(2014) T.E. Silva et al.   DIABETES & METABOLISM

Lactobacillus rhamnosus GG Protects against Non-Alcoholic Fatty Liver Disease in Mice

(2014) Yvonne Ritze et al.   PLoS One

Relationship Between Visceral Adipose Tissue and Adiponectin, Inflammatory Markers and Thyroid Hormones in Obese Males with Hepatosteatosis and Insulin Resistance

(2013) Fatih Ozcelik et al.   ARCHIVES OF MEDICAL RESEARCH

Gender differences in the association of visceral and subcutaneous adiposity with adiponectin in African Americans: the Jackson Heart Study

(2013) Aurelian Bidulescu et al.   BMC Cardiovascular Disorders

Gut microbiota and non-alcoholic fatty liver disease: new insights

(2013) J. Aron-Wisnewsky et al.   CLINICAL MICROBIOLOGY AND INFECTION

Proinflammatory, anti-inflammatory cytokines and adiponkines in students with central obesity

(2013) Amany El-Wakkad et al.   CYTOKINE

The expanding role of fish models in understanding non-alcoholic fatty liver disease

(2013) Y. Asaoka et al.   Disease Models & Mechanisms

Association of the +45T>G adiponectin gene polymorphism with insulin resistance in non-diabetic Saudi women

(2013) Amal Mohammed Husein Mackawy   GENE

Genetic association of ADIPOQ gene variants with type 2 diabetes, obesity and serum adiponectin levels in south Indian population

(2013) Kandaswamy Ramya et al.   GENE

Inflammation as a potential link between nonalcoholic fatty liver disease and insulin resistance

(2013) Mohamed Asrih et al.   JOURNAL OF ENDOCRINOLOGY

High-Fat Diet Induces Leptin Resistance in Leptin-Deficient Mice

(2013) C. E. Koch et al.   JOURNAL OF NEUROENDOCRINOLOGY

Adiponectin Gene Variant Interacts with Fish Oil Supplementation to Influence Serum Adiponectin in Older Individuals

(2013) et al.   JOURNAL OF NUTRITION

Retinol binding protein-4 circulating levels were higher in nonalcoholic fatty liver disease vs. histologically normal liver from morbidly obese women

(2013) Ximena Terra et al.   Obesity

Alterations in adipocytokines and cGMP homeostasis in morbid obesity patients reverse after bariatric surgery

(2013) Vicente Felipo et al.   Obesity

Association between Serum Leptin Concentrations and Insulin Resistance: A Population-Based Study from China

(2013) Hui Zuo et al.   PLoS One

Quercetin ameliorate insulin resistance and up-regulates cellular antioxidants during oleic acid induced hepatic steatosis in HepG2 cells

(2013) Satyakumar Vidyashankar et al.   TOXICOLOGY IN VITRO

Fructose as a key player in the development of fatty liver disease

(2013) Metin Basaranoglu   WORLD JOURNAL OF GASTROENTEROLOGY

What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

(2013) Carmine Finelli   WORLD JOURNAL OF GASTROENTEROLOGY

From fatty liver to fibrosis: A tale of “second hit”

(2013) Metin Basaranoglu   WORLD JOURNAL OF GASTROENTEROLOGY

Pathogenesis of hepatic steatosis: The link between hypercortisolism and non-alcoholic fatty liver disease

(2013) Giovanni Tarantino   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of probiotics on nonalcoholic fatty liver disease: A meta-analysis

(2013) Yan-Yan Ma   WORLD JOURNAL OF GASTROENTEROLOGY

Effects of glutamine on oxidative stress and nuclear factor-κB expression in the livers of rats with nonalcoholic fatty liver disease

(2013) ZHIHUI LIN et al.   Experimental and Therapeutic Medicine

Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: Role of adipokines

(2013) Elaine Hui et al.   Journal of Diabetes Investigation

Reprint of “cDNA Cloning and Expression of a Novel Adipose Specific Collagen-like Factor, apM1 (dioseost Abundant Gene Transcript 1)”

(2012) Kazuhisa Maeda   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New insights into the impact of the intestinal microbiota on health and disease: a symposium report

(2012) Linda V. Thomas et al.   BRITISH JOURNAL OF NUTRITION

Dietary quercetin ameliorates nonalcoholic steatohepatitis induced by a high-fat diet in gerbils

(2012) Hua-Zhong Ying et al.   FOOD AND CHEMICAL TOXICOLOGY

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology

(2012) Naga Chalasani et al.   GASTROENTEROLOGY

Relationship Between Leptin G2548A and Leptin Receptor Q223R Gene Polymorphisms and Obesity and Metabolic Syndrome Risk in Tunisian Volunteers

(2012) Imen Boumaiza et al.   Genetic Testing and Molecular Biomarkers

Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice

(2012) Kouichi Miura et al.   HEPATOLOGY

Serum biomarkers in type 2 diabetic patients with non-alcoholic steatohepatitis and advanced fibrosis

(2012) Nathalie Carvalho Leite et al.   HEPATOLOGY RESEARCH

Rosuvastatin ameliorates high-fat and high-cholesterol diet-induced nonalcoholic steatohepatitis in rats

(2012) Yoshihisa Okada et al.   LIVER INTERNATIONAL

The Impact of Leptin and Adiponectin on Incident Type 2 Diabetes Is Modified by Sex and Insulin Resistance

(2012) Mikael Lilja et al.   Metabolic Syndrome and Related Disorders

Dietary-fat-induced taurocholic acid promotes pathobiont expansion and colitis in Il10 −/− mice

(2012) Suzanne Devkota et al.   NATURE

Genetically modified mouse models for the study of nonalcoholic fatty liver disease

(2012) Perumal Nagarajan   WORLD JOURNAL OF GASTROENTEROLOGY

Animal models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2012) Yoshihisa Takahashi   WORLD JOURNAL OF GASTROENTEROLOGY

Role of cytokines and chemokines in non-alcoholic fatty liver disease

(2012) Vincent Braunersreuther   WORLD JOURNAL OF GASTROENTEROLOGY

Role of Adipokines and Other Inflammatory Mediators in Gestational Diabetes Mellitus and Previous Gestational Diabetes Mellitus

(2012) Nikolaos Vrachnis et al.   International Journal of Endocrinology

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

High liver RBP4 protein content is associated with histological features in patients with genotype 1 chronic hepatitis C and with nonalcoholic steatohepatitis

(2011) Salvatore Petta et al.   DIGESTIVE AND LIVER DISEASE

Metabolic adaptation to a high-fat diet is associated with a change in the gut microbiota

(2011) Matteo Serino et al.   GUT

Association of tumor necrosis factor-α gene promoter polymorphism at sites -308 and -238 with non-alcoholic fatty liver disease: A meta-analysis

(2011) Ji-kai Wang et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Lack of interleukin-1α or interleukin-1β inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice

(2011) Yehuda Kamari et al.   JOURNAL OF HEPATOLOGY

Serum interleukin 1 receptor antagonist as an independent marker of non-alcoholic steatohepatitis in humans

(2011) Jussi Pihlajamäki et al.   JOURNAL OF HEPATOLOGY

Blockade of IL-6 signaling exacerbates liver injury and suppresses antiapoptotic gene expression in methionine choline-deficient diet-Fed db/db mice

(2011) Kanji Yamaguchi et al.   LABORATORY INVESTIGATION

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(2011) Alexander Moschen et al.   MOLECULAR MEDICINE

Association of Obestatin, Ghrelin, and Inflammatory Cytokines in Obese Patients with Non-alcoholic Fatty Liver Disease

(2011) Michael Estep et al.   OBESITY SURGERY

Fish oil improves lipid metabolism and ameliorates inflammation in patients with metabolic syndrome: Impact of nonalcoholic fatty liver disease

(2011) Mohammed M. H. Al-Gayyar et al.   PHARMACEUTICAL BIOLOGY

Dietary Oleate Has Beneficial Effects on Every Step of Non-Alcoholic Fatty Liver Disease Progression in a Methionine- and Choline-Deficient Diet-Fed Animal Model

(2011) Ji Young Lee et al.   Diabetes & Metabolism Journal

Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action

(2010) F. Thomas Wunderlich et al.   Cell Metabolism

Disruption of Hepatic Leptin Signaling Protects Mice From Age- and Diet-Related Glucose Intolerance

(2010) F. K. Huynh et al.   DIABETES

Serum retinol-binding protein 4 in patients with nonalcoholic fatty liver disease: does it have a significant impact on pathogenesis?

(2010) Cem Cengiz et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice

(2010) Kouichi Miura et al.   GASTROENTEROLOGY

Adiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS-3)

(2010) Jeffrey A. Handy et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PARP1 deficiency exacerbates diet-induced obesity in mice

(2010) Kishor Devalaraja-Narashimha et al.   JOURNAL OF ENDOCRINOLOGY

Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice

(2010) Valentina Volynets et al.   JOURNAL OF LIPID RESEARCH

Dietary α- and γ-tocopherol supplementation attenuates lipopolysaccharide-induced oxidative stress and inflammatory-related responses in an obese mouse model of nonalcoholic steatohepatitis

(2010) Min-Yu Chung et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice

(2010) Giridhar Kanuri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Endotoxin and Plasminogen Activator Inhibitor-1 Serum Levels Associated With Nonalcoholic Steatohepatitis in Children

(2010) Anna Alisi et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice

(2010) Kanji Yamaguchi et al.   LABORATORY INVESTIGATION

The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2010) Qing Liu et al.   Lipids in Health and Disease

The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice

(2010) Livia de Fraia Pinto et al.   LIVER INTERNATIONAL

Increased Soluble Leptin Receptor Levels in Morbidly Obese Patients With Insulin Resistance and Nonalcoholic Fatty Liver Disease

(2010) Valentina Medici et al.   Obesity

Hyperleptinemia Is Required for the Development of Leptin Resistance

(2010) Zachary A. Knight et al.   PLoS One

Circulating levels of interleukin-18 in patients with non-alcoholic fatty liver disease

(2010) Serkan Tapan et al.   SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION

Serotonin reuptake transporter (SERT) plays a critical role in the onset of fructose-induced hepatic steatosis in mice

(2009) Synia Haub et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway

(2009) Motoharu Awazawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The metabolic syndrome: how it may influence hepatic stellate cell activation and hepatic fibrosis

(2009) Nicolas Lanthier et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Genetic polymorphisms in non-alcoholic fatty liver disease: Interleukin-6−174G/C polymorphism is associated with non-alcoholic steatohepatitis

(2009) L. Carulli et al.   DIGESTIVE AND LIVER DISEASE

Acylated and nonacylated ghrelin levels and their associations with insulin resistance in obese and normal weight children with metabolic syndrome

(2009) Lucia Pacifico et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Could inflammatory markers help diagnose nonalcoholic steatohepatitis?

(2009) Giovanni Tarantino et al.   EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY

Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis

(2009) Yuzo Kodama et al.   GASTROENTEROLOGY

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Kupffer cells promote hepatic steatosis via interleukin-1β-dependent suppression of peroxisome proliferator-activated receptor α activity

(2009) Rinke Stienstra et al.   HEPATOLOGY

Toll-like receptor 4 is involved in the development of fructose-induced hepatic steatosis in mice

(2009) Astrid Spruss et al.   HEPATOLOGY

Circulating and liver tissue levels of retinol-binding protein-4 in non-alcoholic fatty liver disease

(2009) Maria Schina et al.   HEPATOLOGY RESEARCH

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes

(2009) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

Serum Retinol-binding Protein 4 Levels in Patients With Nonalcoholic Fatty Liver Disease

(2009) Naim Alkhouri et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Serum adipokine levels predictive of liver injury in non-alcoholic fatty liver disease

(2009) Maud Lemoine et al.   LIVER INTERNATIONAL

Adipokines in Nonalcoholic Steatohepatitis: From Pathogenesis to Implications in Diagnosis and Therapy

(2009) Emmanuel A. Tsochatzis et al.   MEDIATORS OF INFLAMMATION

Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome

(2009) E. Maury et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Liver NF-κB and AP-1 DNA Binding in Obese Patients

(2009) Luis A. Videla et al.   Obesity

Adiponectin in health and disease: evaluation of adiponectin-targeted drug development strategies

(2009) Shoba Shetty et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Increased Hepatic and Circulating Interleukin-6 Levels in Human Nonalcoholic Steatohepatitis

(2008) Anna Wieckowska et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Leptin resistance: a prediposing factor for diet-induced obesity

(2008) Philip J. Scarpace et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Post-translational modifications of adiponectin: mechanisms and functional implications

(2008) Yu Wang et al.   BIOCHEMICAL JOURNAL

Identification of the Acyltransferase that Octanoylates Ghrelin, an Appetite-Stimulating Peptide Hormone

(2008) Jing Yang et al.   CELL

Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity

(2008) O. Osborn et al.   CYTOKINE

Influence of Visfatin on Histopathological Changes of Non-alcoholic Fatty Liver Disease

(2008) R. Aller et al.   DIGESTIVE DISEASES AND SCIENCES

Total adiponectin and adiponectin multimeric complexes in relation to weight loss-induced improvements in insulin sensitivity in obese women: the NUGENOB study.

(2008) J Polak et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Retinol-binding protein 4 is associated with insulin resistance, but appears unsuited for metabolic screening in women with polycystic ovary syndrome.

(2008) Matthias Möhlig et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Reduced response to adiponectin and lower abundance of adiponectin receptor proteins in type 2 diabetic monocytes

(2008) Johanna Weigert et al.   FEBS LETTERS

Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice

(2008) Kun L. Ma et al.   HEPATOLOGY

Expression of adiponectin and its receptors in livers of morbidly obese patients with non-alcoholic fatty liver disease

(2008) Hong Ma et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Antibiotics protect against fructose-induced hepatic lipid accumulation in mice: Role of endotoxin

(2008) Ina Bergheim et al.   JOURNAL OF HEPATOLOGY

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

(2008) Josef S Smolen et al.   LANCET

Effect of leptin infusion on insulin sensitivity and lipid metabolism in diet-induced lipodystrophy model mice

(2008) Koji Nagao et al.   Lipids in Health and Disease

Pattern of Expression of Adiponectin Receptors in Human Liver and its Relation to Nonalcoholic Steatohepatitis

(2008) M. Nannipieri et al.   OBESITY SURGERY

Serum adipokine levels in chronic liver diseases: Association of resistin levels with fibrosis severity

(2008) Emmanuel Tsochatzis et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Inhibition of hepatic interleukin-18 production by rosiglitazone in a rat model of nonalcoholic fatty liver disease

(2008) Hai-Ning Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY