Pichia pastoris-expressed dengue 3 envelope-based virus-like particles elicit predominantly domain III-focused high titer neutralizing antibodies

Dengue Virus Infection with Highly Neutralizing Levels of Cross-Reactive Antibodies Causes Acute Lethal Small Intestinal Pathology without a High Level of Viremia in Mice

(2015) Satoru Watanabe et al.   JOURNAL OF VIROLOGY

Efficacy of a Tetravalent Dengue Vaccine in Children in Latin America

(2015) Luis Villar et al.   NEW ENGLAND JOURNAL OF MEDICINE

Clinical efficacy and safety of a novel tetravalent dengue vaccine in healthy children in Asia: a phase 3, randomised, observer-masked, placebo-controlled trial

(2014) Maria Rosario Capeding et al.   LANCET

Functional Analysis of Antibodies against Dengue Virus Type 4 Reveals Strain-Dependent Epitope Exposure That Impacts Neutralization and Protection

(2013) S. Sukupolvi-Petty et al.   JOURNAL OF VIROLOGY

Dengue vaccine efficacy trial: does interference cause failure?

(2013) Sathyamangalam Swaminathan et al.   LANCET INFECTIOUS DISEASES

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Pichia pastoris-Expressed Dengue 2 Envelope Forms Virus-Like Particles without Pre-Membrane Protein and Induces High Titer Neutralizing Antibodies

(2013) Shailendra Mani et al.   PLoS One

The Potent and Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1C19 Reveals a Unique Cross-Reactive Epitope on the bc Loop of Domain II of the Envelope Protein

(2013) S. A. Smith et al.   mBio

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

(2012) Arunee Sabchareon et al.   LANCET

Chimeric Hepatitis B core antigen virus-like particles displaying the envelope domain III of dengue virus type 2

(2012) Upasana Arora et al.   JOURNAL OF NANOBIOTECHNOLOGY

Applications of viral nanoparticles in medicine

(2011) Ibrahim Yildiz et al.   CURRENT OPINION IN BIOTECHNOLOGY

Unique challenges faced by the clinical evaluation of dengue vaccines

(2011) Robert Edelman   Expert Review of Vaccines

The Necessity and Quandaries of Dengue Vaccine Development

(2011) S. J. Thomas   JOURNAL OF INFECTIOUS DISEASES

Persistence of Circulating Memory B Cell Clones with Potential for Dengue Virus Disease Enhancement for Decades following Infection

(2011) S. A. Smith et al.   JOURNAL OF VIROLOGY

Virus-like particle production with yeast: ultrastructural and immunocytochemical insights into Pichia pastoris producing high levels of the Hepatitis B surface antigen

(2011) Heinrich Lünsdorf et al.   Microbial Cell Factories

Next generation dengue vaccines: A review of candidates in preclinical development

(2011) Julia Schmitz et al.   VACCINE

In-Depth Analysis of the Antibody Response of Individuals Exposed to Primary Dengue Virus Infection

(2011) Ruklanthi de Alwis et al.   PLoS Neglected Tropical Diseases

Evaluation of Extracellular Subviral Particles of Dengue Virus Type 2 and Japanese Encephalitis Virus Produced by Spodoptera frugiperda Cells for Use as Vaccine and Diagnostic Antigens

(2010) M. Kuwahara et al.   Clinical and Vaccine Immunology

Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3

(2010) James D. Brien et al.   JOURNAL OF VIROLOGY

Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2

(2010) S. Sukupolvi-Petty et al.   JOURNAL OF VIROLOGY

Cross-Reacting Antibodies Enhance Dengue Virus Infection in Humans

(2010) W. Dejnirattisai et al.   SCIENCE

Immature Dengue Virus: A Veiled Pathogen?

(2010) Izabela A. Rodenhuis-Zybert et al.   PLoS Pathogens

Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 Viruses

(2010) Wahala M. P. B. Wahala et al.   PLoS Pathogens

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

(2010) Bimmi Shrestha et al.   PLoS Pathogens

Dengue: Recent Advances in Biology and Current Status of Translational Research

(2009) Sathyamangalam Swaminathan et al.   CURRENT MOLECULAR MEDICINE

Efficient Assembly and Secretion of Recombinant Subviral Particles of the Four Dengue Serotypes Using Native prM and E Proteins

(2009) Pei-Gang Wang et al.   PLoS One

Recombinant dengue virus-like particles from Pichia pastoris: efficient production and immunological properties

(2009) Wenquan Liu et al.   VIRUS GENES