Functional Analysis of Antibodies against Dengue Virus Type 4 Reveals Strain-Dependent Epitope Exposure That Impacts Neutralization and Protection

Immature and Mature Dengue Serotype 1 Virus Structures Provide Insight into the Maturation Process

(2013) V. A. Kostyuchenko et al.   JOURNAL OF VIROLOGY

Structural Changes in Dengue Virus When Exposed to a Temperature of 37 C

(2013) G. Fibriansah et al.   JOURNAL OF VIROLOGY

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

Dengue structure differs at the temperatures of its human and mosquito hosts

(2013) X. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emergence potential of sylvatic dengue virus type 4 in the urban transmission cycle is restrained by vaccination and homotypic immunity

(2013) Anna P. Durbin et al.   VIROLOGY

Therapeutic Efficacy of Antibodies Lacking FcγR against Lethal Dengue Virus Infection Is Due to Neutralizing Potency and Blocking of Enhancing Antibodies

(2013) Katherine L. Williams et al.   PLoS Pathogens

The Economic Burden of Dengue

(2012) Duane J. Gubler   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Mechanistic Study of Broadly Neutralizing Human Monoclonal Antibodies against Dengue Virus That Target the Fusion Loop

(2012) J. M. Costin et al.   JOURNAL OF VIROLOGY

Dengue vaccine development: a 75% solution?

(2012) Scott B Halstead   LANCET

Protective efficacy of the recombinant, live-attenuated, CYD tetravalent dengue vaccine in Thai schoolchildren: a randomised, controlled phase 2b trial

(2012) Arunee Sabchareon et al.   LANCET

Cryo-EM structure of the mature dengue virus at 3.5-Å resolution

(2012) Xiaokang Zhang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of human neutralizing antibodies that bind to complex epitopes on dengue virions

(2012) R. de Alwis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody

(2012) E. P. Teoh et al.   Science Translational Medicine

Mechanism of Dengue Virus Broad Cross-Neutralization by a Monoclonal Antibody

(2012) Joseph J.B. Cockburn et al.   STRUCTURE

A Model of DENV-3 Infection That Recapitulates Severe Disease and Highlights the Importance of IFN-γ in Host Resistance to Infection

(2012) Vivian V. Costa et al.   PLoS Neglected Tropical Diseases

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity

(2012) Chia-Yi Yu et al.   PLoS Pathogens

Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

(2012) S. Kyle Austin et al.   PLoS Pathogens

DENV Inhibits Type I IFN Production in Infected Cells by Cleaving Human STING

(2012) Sebastian Aguirre et al.   PLoS Pathogens

Poorly Neutralizing Cross-Reactive Antibodies against the Fusion Loop of West Nile Virus Envelope Protein Protect In Vivo via Fc  Receptor and Complement-Dependent Effector Mechanisms

(2011) M. R. Vogt et al.   JOURNAL OF VIROLOGY

Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step

(2011) M. C. Sabo et al.   JOURNAL OF VIROLOGY

A Single Amino Acid in Nonstructural Protein NS4B Confers Virulence to Dengue Virus in AG129 Mice through Enhancement of Viral RNA Synthesis

(2011) D. Grant et al.   JOURNAL OF VIROLOGY

From research to phase III: Preclinical, industrial and clinical development of the Sanofi Pasteur tetravalent dengue vaccine

(2011) Bruno Guy et al.   VACCINE

The lectin pathway of complement activation contributes to protection from West Nile virus infection

(2011) Anja Fuchs et al.   VIROLOGY

Genetic and phenotypic characterization of sylvatic dengue virus type 4 strains

(2011) S.L. Rossi et al.   VIROLOGY

Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature

(2011) Michelle C. Sabo et al.   VIROLOGY

In-Depth Analysis of the Antibody Response of Individuals Exposed to Primary Dengue Virus Infection

(2011) Ruklanthi de Alwis et al.   PLoS Neglected Tropical Diseases

A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus

(2011) Kimberly A. Dowd et al.   PLoS Pathogens

Enhanced Infection of Liver Sinusoidal Endothelial Cells in a Mouse Model of Antibody-Induced Severe Dengue Disease

(2010) Raphaël M. Zellweger et al.   Cell Host & Microbe

Mouse STAT2 Restricts Early Dengue Virus Replication

(2010) Joseph Ashour et al.   Cell Host & Microbe

The Human Immune Response to Dengue Virus Is Dominated by Highly Cross-Reactive Antibodies Endowed with Neutralizing and Enhancing Activity

(2010) Martina Beltramello et al.   Cell Host & Microbe

Characterization of a dengue type-specific epitope on dengue 3 virus envelope protein domain III

(2010) K. Matsui et al.   JOURNAL OF GENERAL VIROLOGY

Genotype-Specific Neutralization and Protection by Antibodies against Dengue Virus Type 3

(2010) James D. Brien et al.   JOURNAL OF VIROLOGY

Structure and Function Analysis of Therapeutic Monoclonal Antibodies against Dengue Virus Type 2

(2010) S. Sukupolvi-Petty et al.   JOURNAL OF VIROLOGY

Neutralization of West Nile virus by cross-linking of its surface proteins with Fab fragments of the human monoclonal antibody CR4354

(2010) B. Kaufmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural Strain Variation and Antibody Neutralization of Dengue Serotype 3 Viruses

(2010) Wahala M. P. B. Wahala et al.   PLoS Pathogens

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

(2010) Bimmi Shrestha et al.   PLoS Pathogens

Lethal Antibody Enhancement of Dengue Disease in Mice Is Prevented by Fc Modification

(2010) Scott J. Balsitis et al.   PLoS Pathogens

Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody

(2009) Mickaël V Cherrier et al.   EMBO JOURNAL

Atomic-Level Mapping of Antibody Epitopes on a GPCR

(2009) Cheryl Paes et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Association of the pr Peptides with Dengue Virus at Acidic pH Blocks Membrane Fusion

(2009) I.-M. Yu et al.   JOURNAL OF VIROLOGY

NS5 of Dengue Virus Mediates STAT2 Binding and Degradation

(2009) J. Ashour et al.   JOURNAL OF VIROLOGY

Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion

(2009) V. Nayak et al.   JOURNAL OF VIROLOGY

Essential role of platelet-activating factor receptor in the pathogenesis of Dengue virus infection

(2009) D. G. Souza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus

(2008) G. D. Gromowski et al.   JOURNAL OF VIROLOGY

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins

(2008) Shee-Mei Lok et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Flavivirus Precursor Membrane-Envelope Protein Complex: Structure and Maturation

(2008) L. Li et al.   SCIENCE

Structure of the Immature Dengue Virus at Low pH Primes Proteolytic Maturation

(2008) I-M. Yu et al.   SCIENCE

Genetic and phenotypic characterization of sylvatic dengue virus type 2 strains

(2008) Nikos Vasilakis et al.   VIROLOGY

Characterization of dengue complex-reactive epitopes on dengue 3 virus envelope protein domain III

(2008) Kiyohiko Matsui et al.   VIROLOGY

Maturation of West Nile Virus Modulates Sensitivity to Antibody-Mediated Neutralization

(2008) Steevenson Nelson et al.   PLoS Pathogens