Roles and functions of HIV-1 Tat protein in the CNS: an overview

Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: Involvement of β1 integrins

(2013) Honghong Yao et al.   FASEB JOURNAL

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

Role of Endolysosomes in HIV-1 Tat-Induced Neurotoxicity

(2012) Liang Hui et al.   ASN Neuro

The NF-κB target genes ICAM-1 and VCAM-1 are differentially regulated during spontaneous differentiation of Caco-2 cells

(2012) Erhan Astarci et al.   FEBS Journal

Use of John Cunningham virus polymerase chain reaction in the diagnosis of progressive multifocal leucoencephalopathy - A rare presenting manifestation in an HIV-positive patient

(2012) C Wattal et al.   Indian Journal of Medical Microbiology

Akinetic Mutism Caused by HIV-associated Progressive Multifocal Leukoencephalopathy was Successfully Treated with Mefloquine: A Serial Multimodal MRI Study

(2012) Kasane Naito et al.   INTERNAL MEDICINE

Favourable outcome of progressive multifocal leukoencephalopathy with mefloquine treatment in combination with antiretroviral therapy in an HIV-infected patient

(2012) E Adachi et al.   INTERNATIONAL JOURNAL OF STD & AIDS

HIV-1 Tat Protein Decreases Dopamine Transporter Cell Surface Expression and Vesicular Monoamine Transporter-2 Function in Rat Striatal Synaptosomes

(2012) Narasimha M. Midde et al.   Journal of Neuroimmune Pharmacology

Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

(2012) Crystal Bethel-Brown et al.   Journal of Neuroinflammation

HIV-1 Tat C-mediated regulation of tumor necrosis factor receptor-associated factor-3 by microRNA 32 in human microglia

(2012) Ritu Mishra et al.   Journal of Neuroinflammation

LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein

(2012) Daniel F Marker et al.   Journal of Neuroinflammation

Human Immunodeficiency Virus Type 1 (HIV-1) Transactivator of Transcription through Its Intact Core and Cysteine-Rich Domains Inhibits Wnt/ -Catenin Signaling in Astrocytes: Relevance to HIV Neuropathogenesis

(2012) L. J. Henderson et al.   JOURNAL OF NEUROSCIENCE

Different NMDA receptor subtypes mediate induction of long-term potentiation and two forms of short-term potentiation at CA1 synapses in rat hippocampusin vitro

(2012) Arturas Volianskis et al.   JOURNAL OF PHYSIOLOGY-LONDON

MicroRNAs in learning, memory, and neurological diseases

(2012) W. Wang et al.   LEARNING & MEMORY

Involvement of the p53 and p73 transcription factors in neuroAIDS

(2011) Ruma Mukerjee et al.   CELL CYCLE

Toll-like Receptor Expression and Activation in Astroglia: Differential Regulation by HIV-1 Tat, gp120, and Morphine

(2011) Nazira El-Hage et al.   IMMUNOLOGICAL INVESTIGATIONS

HIV-1 Tat Protein Promotes Neuronal Dysfunction through Disruption of MicroRNAs

(2011) J. Robert Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deregulation of microRNAs by HIV-1 Vpr Protein Leads to the Development of Neurocognitive Disorders

(2011) Ruma Mukerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIV-1 Tat-Mediated Induction of Platelet-Derived Growth Factor in Astrocytes: Role of Early Growth Response Gene 1

(2011) Crystal Bethel-Brown et al.   JOURNAL OF IMMUNOLOGY

Methamphetamine and HIV-1 Tat Down Regulate β-catenin Signaling: Implications for Methampetamine Abuse and HIV-1 Co-morbidity

(2011) Amit Sharma et al.   Journal of Neuroimmune Pharmacology

Human Immunodeficiency Virus Infection of Human Astrocytes Disrupts Blood-Brain Barrier Integrity by a Gap Junction-Dependent Mechanism

(2011) E. A. Eugenin et al.   JOURNAL OF NEUROSCIENCE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Mechanisms of HIV-tat-Induced Phosphorylation of N-Methyl-d-Aspartate Receptor Subunit 2A in Human Primary Neurons

(2010) Jessie E. King et al.   AMERICAN JOURNAL OF PATHOLOGY

HIV-1 Tat protein enhances RANKL/M-CSF-mediated osteoclast differentiation

(2010) Davide Gibellini et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Phosphatidylinositol-(4,5)-bisphosphate enables efficient secretion of HIV-1 Tat by infected T-cells

(2010) Fabienne Rayne et al.   EMBO JOURNAL

HIV proteins (gp120 and Tat) and methamphetamine in oxidative stress-induced damage in the brain: Potential role of the thiol antioxidant N-acetylcysteine amide

(2010) Atrayee Banerjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nox2-based NADPH oxidase mediates HIV-1 Tat-induced up-regulation of VCAM-1/ICAM-1 and subsequent monocyte adhesion in human astrocytes

(2010) Ha Yong Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Activation of Egr-1 Expression in Astrocytes by HIV-1 Tat: New Insights into Astrocyte-Mediated Tat Neurotoxicity

(2010) Yan Fan et al.   Journal of Neuroimmune Pharmacology

Human Immunodeficiency Virus-1 Tat Activates Calpain Proteases via the Ryanodine Receptor to Enhance Surface Dopamine Transporter Levels and Increase Transporter-Specific Uptake and Vmax

(2010) S. W. Perry et al.   JOURNAL OF NEUROSCIENCE

Interactive role of human immunodeficiency virus type 1 (HIV-1) clade-specific Tat protein and cocaine in blood-brain barrier dysfunction: Implications for HIV-1–associated neurocognitive disorder

(2010) Nimisha Gandhi et al.   JOURNAL OF NEUROVIROLOGY

HIV-associated neurocognitive disorders before and during the era of combination antiretroviral therapy: differences in rates, nature, and predictors

(2010) Robert K. Heaton et al.   JOURNAL OF NEUROVIROLOGY

HIV-1 Tat-induced platelet activation and release of CD154 contribute to HIV-1-associated autoimmune thrombocytopenia

(2010) J. WANG et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

HIV-1 Tat Assembles a Multifunctional Transcription Elongation Complex and Stably Associates with the 7SK snRNP

(2010) Bijan Sobhian et al.   MOLECULAR CELL

Microglia in neurodegenerative disease

(2010) V. Hugh Perry et al.   Nature Reviews Neurology

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

HIV-Tat elicits microglial glutamate release: Role of NAPDH oxidase and the cystine–glutamate antiporter

(2010) Sunita Gupta et al.   NEUROSCIENCE LETTERS

Differences in NMDA Receptor Expression During Human Development Determine the Response of Neurons to HIV-Tat-mediated Neurotoxicity

(2010) E. A. Eugenin et al.   NEUROTOXICITY RESEARCH

Subcellular localization of the interaction between the human immunodeficiency virus transactivator Tat and the nucleosome assembly protein 1

(2009) Alex De Marco et al.   AMINO ACIDS

The Glial Nature of Embryonic and Adult Neural Stem Cells

(2009) Arnold Kriegstein et al.   Annual Review of Neuroscience

TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway

(2009) H Yao et al.   CELL DEATH AND DIFFERENTIATION

The HIV-1 Viral Protein Tat Increases Glutamate and Decreases GABA Exocytosis from Human and Mouse Neocortical Nerve Endings

(2009) Veronica Musante et al.   CEREBRAL CORTEX

Intact Lipid Rafts Regulate HIV-1 Tat Protein-Induced Activation of the Rho Signaling and Upregulation of P-Glycoprotein in Brain Endothelial Cells

(2009) Yu Zhong et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

NADPH Oxidase Drives Cytokine and Neurotoxin Release from Microglia and Macrophages in Response to HIV-Tat

(2008) Jadwiga Turchan–Cholewo et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNAs (miRNAs) in Neurodegenerative Diseases

(2008) Peter T. Nelson et al.   BRAIN PATHOLOGY

HIV-1 Tat and morphine have interactive effects on oligodendrocyte survival and morphology

(2008) Kurt F. Hauser et al.   GLIA

HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?

(2008) Giuseppe Nunnari et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons

(2008) Michael Y. Aksenov et al.   NEUROTOXICOLOGY

Solid Lipid Nanoparticles Enhance the Delivery of the HIV Protease Inhibitor, Atazanavir, by a Human Brain Endothelial Cell Line

(2008) Niladri Chattopadhyay et al.   PHARMACEUTICAL RESEARCH

In vivo microdialysis in awake, freely moving rats demonstrates HIV-1 Tat-induced alterations in dopamine transmission

(2008) Mark J. Ferris et al.   SYNAPSE

From bone marrow to microglia: barriers and avenues

(2008) Nathalie Davoust et al.   TRENDS IN IMMUNOLOGY