Regulation of EGFR signal transduction by analogue-to-digital conversion in endosomes

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

Conformational biosensors reveal GPCR signalling from endosomes

(2013) Roshanak Irannejad et al.   NATURE

Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts

(2012) Dagmar Faust et al.   Cell Communication and Signaling

A General Theoretical Framework to Infer Endosomal Network Dynamics from Quantitative Image Analysis

(2012) Lionel Foret et al.   CURRENT BIOLOGY

Rab5 is necessary for the biogenesis of the endolysosomal system in vivo

(2012) Anja Zeigerer et al.   NATURE

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane

(2012) L. P. Sousa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the EGF Transcriptional Response by Endocytic Sorting

(2012) B. Brankatschk et al.   Science Signaling

Noise in cellular signaling pathways: causes and effects

(2012) John E. Ladbury et al.   TRENDS IN BIOCHEMICAL SCIENCES

Multi-colour direct STORM with red emitting carbocyanines

(2011) André Lampe et al.   BIOLOGY OF THE CELL

Quantitative analysis of cell cycle phase durations and PC12 differentiation using fluorescent biosensors

(2011) Angela T. Hahn et al.   CELL CYCLE

Rapid Phospho-Turnover by Receptor Tyrosine Kinases Impacts Downstream Signaling and Drug Binding

(2011) Laura B. Kleiman et al.   MOLECULAR CELL

Direct stochastic optical reconstruction microscopy with standard fluorescent probes

(2011) Sebastian van de Linde et al.   Nature Protocols

Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics

(2010) Takashi Nakakuki et al.   CELL

Ligand-induced EGF Receptor Oligomerization Is Kinase-dependent and Enhances Internalization

(2010) Erik G. Hofman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epidermal Growth Factor Receptor Activation Remodels the Plasma Membrane Lipid Environment To Induce Nanocluster Formation

(2010) N. Ariotti et al.   MOLECULAR AND CELLULAR BIOLOGY

Systems survey of endocytosis by multiparametric image analysis

(2010) Claudio Collinet et al.   NATURE

Spatial control of EGF receptor activation by reversible dimerization on living cells

(2010) Inhee Chung et al.   NATURE

Signalling ballet in space and time

(2010) Boris N. Kholodenko et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation

(2010) S. Kondo et al.   SCIENCE

An Unbiased Screen Identifies DEP-1 Tumor Suppressor as a Phosphatase Controlling EGFR Endocytosis

(2009) Gabi Tarcic et al.   CURRENT BIOLOGY

Directional Delta and Notch trafficking in Sara endosomes during asymmetric cell division

(2009) F. Coumailleau et al.   NATURE

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes

(2009) Takeshi Ohya et al.   NATURE

Regulation of Epidermal Growth Factor Receptor Trafficking by Lysine Deacetylase HDAC6

(2009) Y. Lissanu Deribe et al.   Science Signaling

The Endosomal Protein Appl1 Mediates Akt Substrate Specificity and Cell Survival in Vertebrate Development

(2008) Annette Schenck et al.   CELL

Clathrin-Mediated Internalization Is Essential for Sustained EGFR Signaling but Dispensable for Degradation

(2008) Sara Sigismund et al.   DEVELOPMENTAL CELL

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Ubc4/5 and c-Cbl Continue to Ubiquitinate EGF Receptor after Internalization to Facilitate Polyubiquitination and Degradation

(2008) Kyohei Umebayashi et al.   MOLECULAR BIOLOGY OF THE CELL

BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals

(2008) Ina Poser et al.   NATURE METHODS

Quantitative proteomics and phosphoproteomics reveal novel insights into complexity and dynamics of the EGFR signaling network

(2008) Sandra Morandell et al.   PROTEOMICS

Endosomal Targeting of MEK2 Requires RAF, MEK Kinase Activity and Clathrin-Dependent Endocytosis

(2008) Emilia Galperin et al.   TRAFFIC