Protein biogenesis machinery is a driver of replicative aging in yeast

Accounting for Experimental Noise Reveals That mRNA Levels, Amplified by Post-Transcriptional Processes, Largely Determine Steady-State Protein Levels in Yeast

(2015) Gábor Csárdi et al.   PLoS Genetics

Nucleosome loss leads to global transcriptional up-regulation and genomic instability during yeast aging

(2014) Z. Hu et al.   GENES & DEVELOPMENT

Calorie restriction does not elicit a robust extension of replicative lifespan in Saccharomyces cerevisiae

(2014) D. H. E. W. Huberts et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FOXO transcription factors: key regulators of cellular quality control

(2014) Ashley E. Webb et al.   TRENDS IN BIOCHEMICAL SCIENCES

Yeast replicative aging: a paradigm for defining conserved longevity interventions

(2013) Brian M. Wasko et al.   FEMS YEAST RESEARCH

The role of mitochondrial DNA mutations and free radicals in disease and ageing

(2013) M. Lagouge et al.   JOURNAL OF INTERNAL MEDICINE

mTOR is a key modulator of ageing and age-related disease

(2013) Simon C. Johnson et al.   NATURE

Ageing as a Risk Factor for Disease

(2012) Teresa Niccoli et al.   CURRENT BIOLOGY

Genome-Scale Studies of Aging: Challenges and Opportunities

(2012) Mark A. McCormick et al.   CURRENT GENOMICS

The Critical Role of Metabolic Pathways in Aging

(2012) N. Barzilai et al.   DIABETES

Large-Scale Quantitative Assessment of Different In-Solution Protein Digestion Protocols Reveals Superior Cleavage Efficiency of Tandem Lys-C/Trypsin Proteolysis over Trypsin Digestion

(2012) Timo Glatter et al.   JOURNAL OF PROTEOME RESEARCH

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

(2012) Adam L. Hughes et al.   NATURE

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

(2012) S. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

A flux-sensing mechanism could regulate the switch between respiration and fermentation

(2011) Daphne H. E. W. Huberts et al.   FEMS YEAST RESEARCH

Pathways Change in Expression During Replicative Aging in Saccharomyces cerevisiae

(2011) G. Yiu et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

Skyline: an open source document editor for creating and analyzing targeted proteomics experiments

(2010) Brendan MacLean et al.   BIOINFORMATICS

Asymmetrically inherited multidrug resistance transporters are recessive determinants in cellular replicative ageing

(2010) Amr Eldakak et al.   NATURE CELL BIOLOGY

Integrated multilaboratory systems biology reveals differences in protein metabolism between two reference yeast strains

(2010) André B. Canelas et al.   Nature Communications

Hot topics in aging research: protein translation, 2009

(2009) Brian K. Kennedy et al.   AGING CELL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

(2009) C. Selman et al.   SCIENCE

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Yeast Life Span Extension by Depletion of 60S Ribosomal Subunits Is Mediated by Gcn4

(2008) Kristan K. Steffen et al.   CELL

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS