A map of directional genetic interactions in a metazoan cell

A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking

(2014) Prisca Liberali et al.   CELL

Detecting epistasis in human complex traits

(2014) Wen-Hua Wei et al.   NATURE REVIEWS GENETICS

Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

(2014) Mohan Babu et al.   PLoS Genetics

Genetic Interaction Networks: Toward an Understanding of Heritability

(2013) Anastasia Baryshnikova et al.   Annual Review of Genomics and Human Genetics

A Systematic Mammalian Genetic Interaction Map Reveals Pathways Underlying Ricin Susceptibility

(2013) Michael C. Bassik et al.   CELL

Mapping genetic interactions in human cancer cells with RNAi and multiparametric phenotyping

(2013) Christina Laufer et al.   NATURE METHODS

Integrating protein-protein interaction networks with phenotypes reveals signs of interactions

(2013) Arunachalam Vinayagam et al.   NATURE METHODS

Quantitative genetic-interaction mapping in mammalian cells

(2013) Assen Roguev et al.   NATURE METHODS

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

(2013) Trudy F. C. Mackay   NATURE REVIEWS GENETICS

Systems genetics approaches to understand complex traits

(2013) Mete Civelek et al.   NATURE REVIEWS GENETICS

Potential of the Synthetic Lethality Principle

(2013) S. M. B. Nijman et al.   SCIENCE

Comprehensive identification of mutational cancer driver genes across 12 tumor types

(2013) David Tamborero et al.   Scientific Reports

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

(2012) Colm J. Ryan et al.   MOLECULAR CELL

The functions and regulation of the PTEN tumour suppressor

(2012) Min Sup Song et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The mystery of missing heritability: Genetic interactions create phantom heritability

(2012) O. Zuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and evaluation of genome-wide libraries for RNA interference screens

(2012) Thomas Horn et al.   GENOME BIOLOGY

A Protein Complex Network of Drosophila melanogaster

(2011) K.G. Guruharsha et al.   CELL

Genetic Interactions in Cancer Progression and Treatment

(2011) Alan Ashworth et al.   CELL

Making sense of cancer genomic data

(2011) Lynda Chin et al.   GENES & DEVELOPMENT

Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype

(2011) Jennifer L. Rohn et al.   JOURNAL OF CELL BIOLOGY

Remodelers Organize Cellular Chromatin by Counteracting Intrinsic Histone-DNA Sequence Preferences in a Class-Specific Manner

(2011) Y. M. Moshkin et al.   MOLECULAR AND CELLULAR BIOLOGY

Mapping of signaling networks through synthetic genetic interaction analysis by RNAi

(2011) Thomas Horn et al.   NATURE METHODS

EBImage--an R package for image processing with applications to cellular phenotypes

(2010) G. Pau et al.   BIOINFORMATICS

Functional Overlap and Regulatory Links Shape Genetic Interactions between Signaling Pathways

(2010) Sake van Wageningen et al.   CELL

Phenotypic Landscape of a Bacterial Cell

(2010) Robert J. Nichols et al.   CELL

Geminin and Brahma act antagonistically to regulate EGFR–Ras–MAPK signaling in Drosophila

(2010) Anabel Herr et al.   DEVELOPMENTAL BIOLOGY

Automated identification of pathways from quantitative genetic interaction data

(2010) Alexis Battle et al.   Molecular Systems Biology

Clustering phenotype populations by genome-wide RNAi and multiparametric imaging

(2010) Florian Fuchs et al.   Molecular Systems Biology

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging

(2010) Michael Held et al.   NATURE METHODS

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Systematic Mapping of Genetic Interaction Networks

(2008) Scott J. Dixon et al.   Annual Review of Genetics

Optimal stepwise experimental design for pairwise functional interaction studies

(2008) Fergal P. Casey et al.   BIOINFORMATICS

The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles

(2008) N. Zielke et al.   GENES & DEVELOPMENT

Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems

(2008) Patrick C. Phillips   NATURE REVIEWS GENETICS

Phosphorylation Networks Regulating JNK Activity in Diverse Genetic Backgrounds

(2008) C. Bakal et al.   SCIENCE