Limits on information transduction through amplitude and frequency regulation of transcription factor activity

High-throughput microfluidics to control and measure signaling dynamics in single yeast cells

(2015) Anders S Hansen et al.   Nature Protocols

Noise and Information Transmission in Promoters with Multiple Internal States

(2014) Georg Rieckh et al.   BIOPHYSICAL JOURNAL

Pulsatile Dynamics in the Yeast Proteome

(2014) Chiraj K. Dalal et al.   CURRENT BIOLOGY

Environmental sensing, information transfer, and cellular decision-making

(2014) Clive G Bowsher et al.   CURRENT OPINION IN BIOTECHNOLOGY

Cellular noise and information transmission

(2014) Andre Levchenko et al.   CURRENT OPINION IN BIOTECHNOLOGY

A dynamic interplay of nucleosome and Msn2 binding regulates kinetics of gene activation and repression following stress

(2014) Nils Elfving et al.   NUCLEIC ACIDS RESEARCH

Multiplexing oscillatory biochemical signals

(2014) Wiet de Ronde et al.   PHYSICAL BIOLOGY

Information transfer by leaky, heterogeneous, protein kinase signaling systems

(2014) M. Voliotis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accurate information transmission through dynamic biochemical signaling networks

(2014) J. Selimkhanov et al.   SCIENCE

The roles and mechanism of ultradian oscillatory expression of the mouse Hes genes

(2014) Yukiko Harima et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Information theory and signal transduction systems: From molecular information processing to network inference

(2014) Siobhan S. Mc Mahon et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

Encoding and Decoding Cellular Information through Signaling Dynamics

(2013) Jeremy E. Purvis et al.   CELL

Fluorescence resonance energy transfer imaging of cell signaling fromin vitrotoin vivo: Basis of biosensor construction, live imaging, and image processing

(2013) Kazuhiro Aoki et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Noise and interlocking signaling pathways promote distinct transcription factor dynamics in response to different stresses

(2013) Natalia Petrenko et al.   MOLECULAR BIOLOGY OF THE CELL

Promoter decoding of transcription factor dynamics involves a trade-off between noise and control of gene expression

(2013) A. S. Hansen et al.   Molecular Systems Biology

Eukaryotic transcriptional dynamics: from single molecules to cell populations

(2013) Antoine Coulon et al.   NATURE REVIEWS GENETICS

Positional information, in bits

(2013) J. O. Dubuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Determinants and Cellular Constraints in Noisy Gene Expression

(2013) A. Sanchez et al.   SCIENCE

Robustness and Compensation of Information Transmission of Signaling Pathways

(2013) S. Uda et al.   SCIENCE

Functional Roles of Pulsing in Genetic Circuits

(2013) J. H. Levine et al.   SCIENCE

Tunable Signal Processing Through Modular Control of Transcription Factor Translocation

(2013) N. Hao et al.   SCIENCE

Oscillatory Control of Factors Determining Multipotency and Fate in Mouse Neural Progenitors

(2013) I. Imayoshi et al.   SCIENCE

Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression

(2013) C. J. Zopf et al.   PLoS Computational Biology

Dynamic Changes in Nucleosome Occupancy Are Not Predictive of Gene Expression Dynamics but Are Linked to Transcription and Chromatin Regulators

(2012) D. J. Huebert et al.   MOLECULAR AND CELLULAR BIOLOGY

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

The application of information theory to biochemical signaling systems

(2012) Alex Rhee et al.   PHYSICAL BIOLOGY

Dynamics of TGF-  signaling reveal adaptive and pulsatile behaviors reflected in the nuclear localization of transcription factor Smad4

(2012) A. Warmflash et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identifying sources of variation and the flow of information in biochemical networks

(2012) C. G. Bowsher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Information theory based approaches to cellular signaling

(2011) Christian Waltermann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Impulse Control: Temporal Dynamics in Gene Transcription

(2011) Nir Yosef et al.   CELL

Sip18 hydrophilin prevents yeast cell death during desiccation stress

(2011) B. Rodríguez-Porrata et al.   JOURNAL OF APPLIED MICROBIOLOGY

Information transmission in genetic regulatory networks: a review

(2011) Gašper Tkačik et al.   JOURNAL OF PHYSICS-CONDENSED MATTER

Stimulus-dependent dynamics of p53 in single cells

(2011) E. Batchelor et al.   Molecular Systems Biology

Bright and stable near-infrared fluorescent protein for in vivo imaging

(2011) Grigory S Filonov et al.   NATURE BIOTECHNOLOGY

Controlling gene expression in response to stress

(2011) Eulàlia de Nadal et al.   NATURE REVIEWS GENETICS

Signal-dependent dynamics of transcription factor translocation controls gene expression

(2011) Nan Hao et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiplexing Biochemical Signals

(2011) Wiet de Ronde et al.   PHYSICAL REVIEW LETTERS

Separating intrinsic from extrinsic fluctuations in dynamic biological systems

(2011) A. Hilfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Information Transduction Capacity of Noisy Biochemical Signaling Networks

(2011) R. Cheong et al.   SCIENCE

Understanding the temporal codes of intra-cellular signals

(2010) Marcelo Behar et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Fundamental limits on the suppression of molecular fluctuations

(2010) Ioannis Lestas et al.   NATURE

Growth control and ribosome biogenesis

(2009) Harri Lempiäinen et al.   CURRENT OPINION IN CELL BIOLOGY

Glucose regulates transcription in yeast through a network of signaling pathways

(2009) Shadia Zaman et al.   Molecular Systems Biology

Information processing and signal integration in bacterial quorum sensing

(2009) Pankaj Mehta et al.   Molecular Systems Biology

Optimizing information flow in small genetic networks

(2009) Gašper Tkačik et al.   PHYSICAL REVIEW E

Mutual Information between Input and Output Trajectories of Biochemical Networks

(2009) Filipe Tostevin et al.   PHYSICAL REVIEW LETTERS

Rewiring the Specificity of Two-Component Signal Transduction Systems

(2008) Jeffrey M. Skerker et al.   CELL

Frequency-modulated nuclear localization bursts coordinate gene regulation

(2008) Long Cai et al.   NATURE

Information flow and optimization in transcriptional regulation

(2008) G. Tkacik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA