DNA hypermethylation appears early and shows increased frequency with dysplasia in Lynch syndrome-associated colorectal adenomas and carcinomas

Colonic Polyps in Lynch Syndrome

(2015) Randall W. Burt   DISEASES OF THE COLON & RECTUM

Epigenetic analysis of sporadic and Lynch-associated ovarian cancers reveals histology-specific patterns of DNA methylation

(2015) Anni Niskakoski et al.   Epigenetics

Prevalence of somatic mutl homolog 1 promoter hypermethylation in Lynch syndrome colorectal cancer

(2014) Leticia Moreira et al.   CANCER

Differences in DNA Methylation Signatures Reveal Multiple Pathways of Progression From Adenoma to Colorectal Cancer

(2014) Yanxin Luo et al.   GASTROENTEROLOGY

Comparison of CpG Island Methylator Phenotype (CIMP) Frequency in Colon Cancer Using Different Probe- and Gene-Specific Scoring Alternatives on Recommended Multi-Gene Panels

(2014) Marianne Berg et al.   PLoS One

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

(2013) Hans F A Vasen et al.   GUT

Cancer-Predicting Gene Expression Changes in Colonic Mucosa of Western Diet Fed Mlh1+/- Mice

(2013) Marjaana Pussila et al.   PLoS One

BRAF mutation in sporadic colorectal cancer and Lynch syndrome

(2013) Alexandra Thiel et al.   VIRCHOWS ARCHIV

Microsatellite Instability and DNA Mismatch Repair Protein Deficiency in Lynch Syndrome Colorectal Polyps

(2012) M. B. Yurgelun et al.   Cancer Prevention Research

Correlation of tumour BRAF mutations andMLH1methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification

(2012) Michael T Parsons et al.   JOURNAL OF MEDICAL GENETICS

Whole-genome methylation analysis of benign and malignant colorectal tumours

(2012) Andrew D Beggs et al.   JOURNAL OF PATHOLOGY

Prevalence of mismatch repair-deficient crypt foci in Lynch syndrome: a pathological study

(2012) Matthias Kloor et al.   LANCET ONCOLOGY

A study of genomic instability in early preneoplastic colonic lesions

(2012) A D Beggs et al.   ONCOGENE

Microsatellite Instability and Colorectal Cancer

(2011) Katherine B. Geiersbach et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Genome-scale analysis of aberrant DNA methylation in colorectal cancer

(2011) T. Hinoue et al.   GENOME RESEARCH

Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway

(2011) L. L. Kodach et al.   GUT

Epigenetics and colorectal cancer

(2011) Victoria Valinluck Lao et al.   Nature Reviews Gastroenterology & Hepatology

Improved Testing for Microsatellite Instability in Colorectal Cancer Using a Simplified 3-Marker Assay

(2010) Iyare Esemuede et al.   ANNALS OF SURGICAL ONCOLOGY

Somatic Hypermethylation of MSH2 Is a Frequent Event in Lynch Syndrome Colorectal Cancers

(2010) T. Nagasaka et al.   CANCER RESEARCH

A review of dietary factors and its influence on DNA methylation in colorectal carcinogenesis

(2010) R.P. Arasaradnam et al.   Epigenetics

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

(2010) A. E. K. Ibrahim et al.   GUT

Methylation tolerance due to an O6-methylguanine DNA methyltransferase (MGMT) field defect in the colonic mucosa: an initiating step in the development of mismatch repair-deficient colorectal cancers

(2010) M. Svrcek et al.   GUT

Epigenomics of human colon cancer

(2010) F. Javier Carmona et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Cancer DNA Methylation: Molecular Mechanisms and Clinical Implications

(2009) M. T. McCabe et al.   CLINICAL CANCER RESEARCH

A Prospective Cohort Study Shows Unique Epigenetic, Genetic, and Prognostic Features of Synchronous Colorectal Cancers

(2009) Katsuhiko Nosho et al.   GASTROENTEROLOGY

DNA methylation within the normal colorectal mucosa is associated with pathway-specific predisposition to cancer

(2009) D L Worthley et al.   ONCOGENE

Sodium-Coupled Transport of the Short Chain Fatty Acid Butyrate by SLC5A8 and Its Relevance to Colon Cancer

(2008) Muthusamy Thangaraju et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Comprehensive Biostatistical Analysis of CpG Island Methylator Phenotype in Colorectal Cancer Using a Large Population-Based Sample

(2008) Katsuhiko Nosho et al.   PLoS One