Role of the planar cell polarity geneProtein tyrosine kinase 7in neural tube defects in humans

Genetic studies ofANKRD6as a molecular switch between Wnt signaling pathways in human neural tube defects

(2014) Redouane Allache et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Planar cell polarity gene mutations contribute to the etiology of human neural tube defects in our population

(2014) Patrizia De Marco et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

ptk7 mutant zebrafish models of congenital and idiopathic scoliosis implicate dysregulated Wnt signalling in disease

(2014) Madeline Hayes et al.   Nature Communications

Ptk7 promotes non-canonical Wnt/PCP-mediated morphogenesis and inhibits Wnt/ -catenin-dependent cell fate decisions during vertebrate development

(2013) M. Hayes et al.   DEVELOPMENT

The many roles of PTK7: A versatile regulator of cell–cell communication

(2012) Hanna Peradziryi et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Role of the planar cell polarity gene CELSR1 in neural tube defects and caudal agenesis

(2012) Redouane Allache et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects

(2012) Diana M. Juriloff et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Convergent extension: using collective cell migration and cell intercalation to shape embryos

(2012) M. Tada et al.   DEVELOPMENT

RACK1 is a novel interaction partner of PTK7 that is required for neural tube closure

(2011) Peter Wehner et al.   DEVELOPMENT

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

(2011) Hanna Peradziryi et al.   EMBO JOURNAL

FZD6is a novel gene for human neural tube defects

(2011) Patrizia De Marco et al.   HUMAN MUTATION

Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects

(2011) Ciprian M. Bosoi et al.   HUMAN MUTATION

Contribution of VANGL2 mutations to isolated neural tube defects

(2010) Z Kibar et al.   CLINICAL GENETICS

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish

(2010) Annie Reynolds et al.   MECHANISMS OF DEVELOPMENT

Regulation of convergence and extension movements during vertebrate gastrulation by the Wnt/PCP pathway

(2009) Isabelle Roszko et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Genetic Basis of Neural Tube Defects

(2009) Alexander G. Bassuk et al.   Seminars in Pediatric Neurology

The Human Gene Mutation Database: 2008 update

(2009) Peter D Stenson et al.   Genome Medicine

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

PTK7 recruits dsh to regulate neural crest migration

(2008) I. Shnitsar et al.   DEVELOPMENT