Article
Neurosciences
Jackson Tyler Boonstra, Stijn Michielse, Alard Roebroeck, Yasin Temel, Ali Jahanshahi
Summary: The emerging field of ultra-high field MRI allows for higher resolution and signal-to-noise ratios in imaging human brains. A custom-built nonferromagnetic container has been developed to address challenges in postmortem imaging and effectively submerge and contain tissue samples for high quality MR imaging of brain material.
Article
Acoustics
S. C. Shelmerdine, N. J. Sebire, O. J. Arthurs
Summary: The diagnostic accuracy of postmortem ultrasound (PM-US) and postmortem magnetic resonance imaging (PM-MRI) for perinatal autopsy is similar, with high concordance rates for overall diagnosis and individual anatomical regions.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2021)
Article
Pediatrics
Nico Hustings, Yannick Thonissen, Lesley Cockmartin, Koen Vanderseypen, Marcella Baldewijns, Luc De Catte, Dietmar Rudolf Thal, Michael Aertsen
Summary: This study aimed to develop an MRI-based scoring system for postmortem fetal brain maceration and correlate it with autopsy results. The brain-specific maceration score showed a strong correlation with fetal brain maceration seen at histopathological exam, and different observers were able to reproduce the score reliably.
PEDIATRIC RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maria da Graca Morais Martin, Vitor Ribeiro Paes, Ellison Fernando Cardoso, Carlos Eduardo Borges Passos Neto, Cristina Takami Kanamura, Claudia da Costa Leite, Maria Concepcion Garcia Otaduy, Renata Aparecida de Almeida Monteiro, Thais Mauad, Luiz Fernando Ferraz da Silva, Luiz Henrique Martins Castro, Paulo Hilario Nascimento Saldiva, Marisa Dolhnikoff, Amaro Nunes Duarte-Neto
Summary: This study investigated brain abnormalities in deceased COVID-19 patients using minimally invasive autopsy. Imaging findings and histological analysis revealed various pathological changes in the brain, including infarcts, hemorrhages, and neuronal degeneration, suggesting the involvement of SARS-CoV-2 in brain damage.
INSIGHTS INTO IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexis Ollitrault, Frederique Charbonneau, Marie-Laure Herdan, Olivier Berges, Kevin Zuber, Lama Giovansili, Pauline Launay, Julien Savatovsky, Augustin Lecler
Summary: This study concluded that compared to a conventional MRI protocol, a single Dixon-T2WI sequence showed higher sensitivity and specificity, fewer artifacts, and increased confidence when assessing thyroid eye disease.
EUROPEAN RADIOLOGY
(2021)
Review
Oncology
Petra J. van Houdt, Yingli Yang, Uulke A. van der Heide
Summary: MRI-guided radiotherapy systems combine adaptive radiotherapy and biological targeting, updating treatment plans regularly to accommodate observed treatment responses. Quantitative imaging biomarkers are necessary for predicting treatment outcomes early in the process. This review provides an overview of the current evidence on the potential of quantitative MRI measurements as imaging biomarkers in MRI-guided radiotherapy systems.
FRONTIERS IN ONCOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jing Zhu, Shuai Ming, Jian Li, Xin Li, Zilan Zhu, Mengxiang Wu, Xinyu Wang, Wei Wei, Karna Ramachandraiah, Fei Ke
Summary: In this study, radiolabeled nanorods were synthesized through a one-pot solvothermal process and transferred to a water solution. The radiolabeled nanorods exhibited excellent colloidal stability and exceptional imaging performance, highlighting their potential use in multimodal imaging.
Review
Chemistry, Multidisciplinary
Jing Yang, Jie Feng, Sugeun Yang, Yikai Xu, Zheyu Shen
Summary: In recent years, exceedingly small magnetic iron oxide nanoparticles (ES-MIONs) have emerged as promising T-1 contrast agents for magnetic resonance imaging (MRI) due to their advantages over traditional contrast agents and conventional magnetic nanoparticles. This review summarizes the synthesis methods, surface modifications, T-1-MRI visual strategies, and imaging-guided cancer therapies of ES-MIONs, aiming to attract extensive interest from researchers and promote their involvement in the development of ES-MIONs based nanoplatforms for tumor theranostics.
Review
Biochemistry & Molecular Biology
Paola Feraco, Rossana Franciosi, Lorena Picori, Federica Scalorbi, Cesare Gagliardo
Summary: The introduction of molecular criteria in glioma classification has practical implications in glioma management. Radiogenomics or imaging genomics involves correlating imaging characteristics with glioma genotypes. Although advanced MRI techniques are widely used, conventional MRI sequences continue to be crucial in studying brain tumors.
Article
Neurosciences
Tomoko Sakai, Junichi Hata, Yuta Shintaku, Hiroki Ohta, Kazumi Sogabe, Susumu Mori, Takako Miyabe-Nishiwaki, Hirotaka James Okano, Yuzuru Hamada, Toshiyuki Hirabayashi, Takafumi Minamimoto, Norihiro Sadato, Hideyuki Okano, Kenichi Oishi
Summary: Comparing the neuroanatomical features of the brain in humans, our evolutionary relatives, and nonhuman primates is crucial for understanding the human brain system and the neural basis of mental and neurological disorders. Research on various species of nonhuman primates is necessary to elucidate the diversity of neuroanatomy features among humans and nonhuman primates. A data-repository of anatomical images obtained using MRI of postmortem brain samples has been developed, and T2-weighted and diffusion tensor images of nine species have been released, contributing to scientific discoveries and promoting animal ethics, animal welfare, and conservation efforts.
Article
Multidisciplinary Sciences
Holger Haas, Sahand Tabatabaei, William Rose, Pardis Sahafi, Michele Piscitelli, Andrew Jordan, Pritam Priyadarsi, Namanish Singh, Ben Yager, Philip J. Poole, Dan Dalacu, Raffi Budakian
Summary: This article combines ultrasensitive force-based spin detection with high-fidelity spin control to achieve NMR diffraction measurement of millions of 31P spins in a nanowire. The experiments demonstrate subangstrom precision in detecting spatial modulation of spins and angstrom-scale displacement of the sample. The diffraction-based techniques extend the capabilities of NMR to the angstrom scale and show the potential of NMRd in probing nanocrystalline materials.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hanns-Christian Breit, Jan Vosshenrich, Verena Hofmann, Thilo Rusche, Balazs K. Kovacs, Michael Bach, Sebastian Manneck, Dorothee Harder
Summary: This study assessed the potential of a 0.55T low-field MRI system in lumbar spine imaging and found that the image quality at 0.55T was lower compared to 1.5T. However, the use of advanced postprocessing techniques improved the imaging quality and the interrater agreement was good.
ACADEMIC RADIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Luca Nagel, Martin Gierse, Wolfgang Gottwald, Zumrud Ahmadova, Martin Grashei, Pascal Wolff, Felix Josten, Senay Karaali, Christoph A. Mueller, Sebastian Lucas, Jochen Scheuer, Christoph Mueller, John Blanchard, Geoffrey J. Topping, Andre Wendlinger, Nadine Setzer, Sandra Suehnel, Jonas Handwerker, Christophoros Vassiliou, Frits H. A. van Heijster, Stephan Knecht, Michael Keim, Franz Schilling, Ilai Schwartz
Summary: Hyperpolarization techniques significantly increase nuclear spin polarization, enabling metabolic MRI. However, the complexity, cost, and slowness of current equipment limit its widespread use. In this study, a polarization procedure using parahydrogen-induced polarization by side-arm hydrogenation (PHIP-SAH) in an automated polarizer is demonstrated, which produces purified, concentrated, and highly hyperpolarized pyruvate solutions within a short time. The results show that PHIP is a viable alternative to established hyperpolarization techniques, with equivalent safety profile, image quality, and quantitative measurements.
Article
Multidisciplinary Sciences
Hu Cheng, Sophia Vinci-Booher, Jian Wang, Bradley Caron, Qiuting Wen, Sharlene Newman, Franco Pestilli
Summary: This study proposes a simple denoising method using a one-dimensional convolutional neural network (1D-CNN) and deep learning to learn from a low-noise dataset, and applies it to high-noise datasets. The results show that this method produces DWI images that are more similar to noise-free ground truth compared to other methods, and also shows promising results in diffusion metrics and tractography.
Article
Nanoscience & Nanotechnology
Anna Koudrina, Erin M. McConnell, Joseph A. Zurakowski, Greg O. Cron, Suzan Chen, Eve C. Tsai, Maria C. DeRosa
Summary: The study successfully prepared a fibrin-targeting MRI contrast agent, Gd(III)-NOTA-FA, which can specifically accumulate at the location of blood clots, enhancing contrast capabilities.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Cardiac & Cardiovascular Systems
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Dries Belsack, Jean-Francois Argacha, Bernard Cosyns, Michel De Maeseneer, Johan De Mey
Summary: This study aimed to investigate the impact of ramus-induced turbulence on FFRCT. The results showed that the presence of a large ramus artery significantly increased FFRCT values and was associated with a higher risk of low FFRCT values.
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
(2023)
Article
Cardiac & Cardiovascular Systems
Shuichiro Kazawa, Carlo de Asmundis, Maysam Al Housari, Gezim Bala, Juan Sieira, Dries Belsack, Johan De Mey, Stijn Lochy, Bert Vandeloo, Jean-Francois Argacha, Pedro Brugada, Gian-Battista Chierchia, Kaoru Tanaka, Erwin Stroeker
Summary: This study evaluates coronary artery disease (CAD) in atrial fibrillation (AF) patients requiring ablation using computed tomography coronary angiography (CTCA)-derived fractional flow reserve (FFR). The results showed similar prevalence of CAD in both the AF group and non-AF group, suggesting shared associated risk factors for CAD and AF.
Article
Neurosciences
B. Tassignon, A. Radwan, J. Blommaert, L. Stas, S. D. Allard, F. De Ridder, E. De Waele, L. C. Bulnes, N. Hoornaert, P. Lacor, E. Lathouwers, R. Mertens, M. Naeyaert, H. Raeymaekers, L. Seyler, A. M. Van Binst, L. Van Imschoot, L. Van Liedekerke, J. Van Schependom, P. Van Schuerbeek, M. Vandekerckhove, R. Meeusen, S. Sunaert, G. Nagels, J. De Mey, K. De Pauw
Summary: This study evaluated the whole-brain structural connectivity and cognitive performance of COVID-19 survivors through brain scans and cognitive tests. The results showed that the adverse effects of COVID-19 on brain functioning and structure decrease over time. However, future research with larger sample sizes, matched control groups, and longer follow-up periods is needed to confirm these findings.
EXPERIMENTAL BRAIN RESEARCH
(2023)
Article
Cardiac & Cardiovascular Systems
Kai Ninomiya, Patrick W. Serruys, Scot Garg, Shinichiro Masuda, Shigetaka Kageyama, Nozomi Kotoku, Marie Angele Morel, Charles Taylor, John D. Puskas, Jagat Narula, Ulrich Schneider, Torsten Doenst, Kaoru Tanaka, Johan De Mey, Mark La Meir, Saima Mushtaq, Antonio L. Bartorelli, Giulio Pompilio, Daniele Andreini, Yoshinobu Onuma
Summary: The feasibility of using CCTA and FFRCT as guidance in the FASTTRACK CABG trial is determined by the need for invasive coronary angiography. According to the SS-2020, the first 57 patients enrolled in the trial received the appropriate revascularization modality, and the DSMB allowed the investigators to continue the study.
CARDIOVASCULAR REVASCULARIZATION MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Stijn E. F. Huys, Benyameen Keelson, Yannick de Brucker, Gert Van Gompel, Johan de Mey, Jos Vander Sloten, Nico Buls
Summary: This study analysed the possibilities of using 4D CT scanning to track patients' mandibles. A new mandibular phantom and a dynamic CT acquisition protocol were used to capture the motion of the mandible. The results showed that this method can accurately evaluate mandibular motion, with radiation doses similar to standard head CT scans.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Mahta Mazloumi, Gert Van Gompel, Kaoru Tanaka, Jean-Francois Argacha, Johan de Mey, Nico Buls
Summary: This study compared the radiation dose between contrast coronary CT angiography (CCTA) and non-contrast calcium scoring CT (CSCT) in cardiac CT. The results showed that doses increased in the aorta, left ventricle, and right ventricle in the CCTA scans compared to the CSCT scans, while the dose in myocardial tissue was not noticeably impacted by the contrast agent. Conclusion: There is a linear causal relation between local contrast agent concentration and increase in radiation dose in cardiac CT, with contrast cardiac CT having an average 55% higher dose to the heart for the same CT exposure.
Article
Radiology, Nuclear Medicine & Medical Imaging
Jakub Ceranka, Frederic Lecouvet, Nicolas Michoux, Johan de Mey, Hubert Raeymaekers, Thierry Metens, Jef Vandemeulebroucke
Summary: This study tested and compared different intensity standardization approaches for whole-body multi-parametric MR images. The piecewise linear intensity standardization approach provided the best compromise between standardization accuracy and method stability. Linear piecewise approaches showed the overall best performance across multiple validation metrics, mostly because of its robustness.
BIOMEDICAL PHYSICS & ENGINEERING EXPRESS
(2023)
Article
Cardiac & Cardiovascular Systems
Maysam Al Housari, Vincenzo Miraglia, Muryo Terasawa, Shuichiro Kazawa, Alvise Del Monte, Gezim Bala, Luigi Pannone, Domenico Giovanni Della Rocca, Bernard Cosyns, Steven Droogmans, Kaoru Tanaka, Dries Belsack, Johan De Mey, Ingrid Overeinder, Alexandre Almorad, Juan Sieira, Pedro Brugada, Andrea Sarkozy, Gian-Battista Chierchia, Carlo de Asmundis, Erwin Stroker
Summary: This study compared the anatomical characteristics of PVs between patients with paroxysmal and persistent AF. It found that patients with persistent AF had larger PV ostial areas, less oval PVs, and different orientations of PVs compared to patients with paroxysmal AF. These anatomical differences may be helpful in choosing the appropriate catheter design and technology for ablation in persistent AF.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Article
Orthopedics
Luca Buzzatti, Benyameen Keelson, Joris Willem van der Voort, Lorenzo Segato, Thierry Scheerlinck, Savanah Hereus, Gert Van Gompel, Jef Vandemeulebroucke, Johan De Mey, Nico Buls, Erik Cattrysse, Ben Serrien
Summary: This study aimed to validate and test a device that simulates realistic knee weight-bearing motion in a horizontal position for dynamic CT acquisition. The results showed that the device was safe and reliable in obtaining dynamic CT images and kinematic parameters of healthy and pathological knees during weight-bearing movement.
Article
Radiology, Nuclear Medicine & Medical Imaging
Pieter Thomas Boonen, Nico Buls, Gert Van Gompel, Hannes Devos, Yannick de Brucker, Tim Leiner, Dimitri Aerden, Johan de Mey, Jef Vandemeulebroucke
Summary: The study proposed a method based on spatio-temporal bolus tracking that leads to stable and physiologically plausible estimation of quantitative hemodynamic parameters in stenotic arteries. These parameters may provide valuable information in the evaluation of PAD and contribute to its diagnosis.
Article
Endocrinology & Metabolism
Steven Raeymaeckers, Maurizio Tosi, Bastiaan Sol, Johan De Mey
Summary: This case report describes a rare occurrence of focal inflammation mimicking thyroid malignancy after sclerotherapy of a thyroid cyst. The medical history of the patient, including prior sclerotherapy, should always be considered when evaluating a suspicious thyroid lesion. Fine needle aspiration should be performed to exclude thyroid cancer.
Article
Cardiac & Cardiovascular Systems
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan de Mey
Summary: Computed tomography-derived fractional flow reserve decreases from the proximal to the distal with coronary stenosis. Paradoxical changes in computed tomography-derived fractional flow reserve require unconventional vessel morphology and specific high driving force. We present a case of marked elevation of computed tomography-derived fractional flow reserve in the middle left anterior descending artery with severe coronary stenosis.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Nozomi Kotoku, Patrick W. Serruys, Shigetaka Kageyama, Scot Garg, Shinichiro Masuda, Kai Ninomiya, Juan B. Grau, Himanshu Gupta, Vikram Agarwal, Marie-Angele Morel, Torsten Doenst, Ulrich Schneider, Kaoru Tanaka, Mark Lameir, Saima Mushtaq, Pontone Gianluca, Giulio Pompilio, Ulf Teichgraeber, John Puskas, Jagat Narula, Johan de Mey, Daniele Andreini, Yoshinobu Onuma
Summary: This study describes the updated approach of using coronary computed tomographic angiography for assessing the completeness of revascularization after coronary artery bypass graft surgery. The results show that CCTA-based coronary artery bypass graft anatomic SYNTAX Score (aSS) has good reproducibility and can be used to quantify the completeness of revascularization in CABG patients.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan De Mey
Summary: This study examined the effects of vessel morphology on computed tomography-derived fractional flow reserve in 1492 outpatients with suspected coronary artery disease. The results showed that, even with similar vessel length and plaque characteristics, there were significant differences in lumen volume and distal computed tomography-derived fractional flow reserve between two patients, indicating that computed tomography-derived fractional flow reserve depends not only on vessel length and plaque characteristics, but also on lumen volume and vessel morphology.
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Dries Belsack, Hannes Devos, Nico Buls, Bernard Cosyns, Jean-Francois Argacha, Michel De Maeseneer, Johan De Mey
Summary: This study found that in vessels with no apparent CAD, vessel length was the most influential factor on FFRCT, followed by the bifurcation angle.
EUROPEAN RADIOLOGY
(2023)