Gene Expression-Genotype Analysis ImplicatesGSDMA,GSDMB, andLRRC3Cas Contributors to Inflammatory Bowel Disease Susceptibility

Disease-Specific Alterations in the Enteric Virome in Inflammatory Bowel Disease

(2015) Jason M. Norman et al.   CELL

An Integrative View of Microbiome-Host Interactions in Inflammatory Bowel Diseases

(2015) Marta Wlodarska et al.   Cell Host & Microbe

Metagenomic Analysis of Microbiome in Colon Tissue from Subjects with Inflammatory Bowel Diseases Reveals Interplay of Viruses and Bacteria

(2015) Weiwei Wang et al.   INFLAMMATORY BOWEL DISEASES

CTCF: an architectural protein bridging genome topology and function

(2014) Chin-Tong Ong et al.   NATURE REVIEWS GENETICS

Overexpression of AIOLOS inhibits cell proliferation and suppresses apoptosis in Nalm-6 cells

(2014) YONG ZHUANG et al.   ONCOLOGY REPORTS

Expression Quantitative Trait Loci Analysis Identifies Associations Between Genotype and Gene Expression in Human Intestine

(2013) Boyko Kabakchiev et al.   GASTROENTEROLOGY

Advances in inflammatory bowel disease pathogenesis: linking host genetics and the microbiome

(2013) Dan Knights et al.   GUT

Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease

(2013) Holm H Uhlig   GUT

Significance of Glycosylphosphatidylinositol-anchored Protein Enrichment in Lipid Rafts for the Control of Autoimmunity

(2013) Yetao Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rhinovirus Wheezing Illness and Genetic Risk of Childhood-Onset Asthma

(2013) Minal Çalışkan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Gene Expression and Thiopurine Metabolite Profiling in Inflammatory Bowel Disease – Novel Clues to Drug Targets and Disease Mechanisms?

(2013) Sofie Haglund et al.   PLoS One

Use of a Multiethnic Approach to Identify Rheumatoid- Arthritis-Susceptibility Loci, 1p36 and 17q12

(2012) Fina A.S. Kurreeman et al.   AMERICAN JOURNAL OF HUMAN GENETICS

LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication

(2012) Klas Haraldson et al.   BIOCHIMIE

The role of neutrophils during intestinal inflammation

(2012) B M Fournier et al.   Mucosal Immunology

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma

(2012) Ke Hao et al.   PLoS Genetics

Clinicopathological and prognostic significance of HER-2/neu and VEGF expression in colon carcinomas

(2011) Qingguo Li et al.   BMC CANCER

Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network

(2011) David R. Crosslin et al.   HUMAN GENETICS

Epithelial barrier: an interface for the cross-communication between gut flora and immune system

(2011) Yoshiyuki Goto et al.   IMMUNOLOGICAL REVIEWS

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Enterocyte death and intestinal barrier maintenance in homeostasis and disease

(2011) Lars Vereecke et al.   TRENDS IN MOLECULAR MEDICINE

GRB7 protein over-expression and clinical outcome in breast cancer

(2010) Betsy Ramsey et al.   BREAST CANCER RESEARCH AND TREATMENT

Variants at IRF5-TNPO3, 17q12-21 and MMEL1 are associated with primary biliary cirrhosis

(2010) Gideon M Hirschfield et al.   NATURE GENETICS

Genome-wide association identifies multiple ulcerative colitis susceptibility loci

(2010) Dermot P B McGovern et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease

(2009) Dominique J. Verlaan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

17q21 variants modify the association between early respiratory infections and asthma

(2009) L. A. M. Smit et al.   EUROPEAN RESPIRATORY JOURNAL

Tyrosine Phosphorylation of Growth Factor Receptor-bound Protein-7 by Focal Adhesion Kinase in the Regulation of Cell Migration, Proliferation, and Tumorigenesis

(2009) Pei-Yu Chu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential aiolos expression in human hematopoietic subpopulations

(2009) Katy Billot et al.   LEUKEMIA RESEARCH

A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium

(2009) Nicole Soranzo et al.   NATURE GENETICS

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Novel gene C17orf37 in 17q12 amplicon promotes migration and invasion of prostate cancer cells

(2009) S Dasgupta et al.   ONCOGENE

A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis

(2008) J. L. Eyles et al.   BLOOD

LRRC3B, Encoding a Leucine-Rich Repeat-Containing Protein, Is a Putative Tumor Suppressor Gene in Gastric Cancer

(2008) M. Kim et al.   CANCER RESEARCH

Mucosal T Cell Proliferation and Apoptosis in Inflammatory Bowel Disease

(2008) Andreas Sturm et al.   CURRENT DRUG TARGETS

Distinctive expression and function of fourGSDMfamily genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium

(2008) Norihisa Saeki et al.   GENES CHROMOSOMES & CANCER

Inflammatory bowel disease unclassified and indeterminate colitis: the role of the pathologist

(2008) K Geboes et al.   JOURNAL OF CLINICAL PATHOLOGY

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS