Bypassing P-Glycoprotein Drug Efflux Mechanisms: Possible Applications in Pharmacoresistant Schizophrenia Therapy

Exosomes as drug delivery vehicles for Parkinson's disease therapy

(2015) Matthew J. Haney et al.   JOURNAL OF CONTROLLED RELEASE

Extracellular vesicles as drug delivery systems: Lessons from the liposome field

(2014) Roy van der Meel et al.   JOURNAL OF CONTROLLED RELEASE

Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function

(2014) Frances Jane Sharom   Frontiers in Oncology

Nano scale self-emulsifying oil based carrier system for improved oral bioavailability of camptothecin derivative by P-Glycoprotein modulation

(2013) Lalit Mohan Negi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Molecular Modeling and Ligand Docking for Solute Carrier (SLC) Transporters

(2013) Avner Schlessinger et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Enhancement effect of P-gp inhibitors on the intestinal absorption and antiproliferative activity of bestatin

(2013) Xiaokui Huo et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Thiomer: A potential carrier for therapeutic delivery

(2013) Rakesh Kumar et al.   REACTIVE & FUNCTIONAL POLYMERS

Intestinal drug transporters: An overview

(2012) Margarida Estudante et al.   ADVANCED DRUG DELIVERY REVIEWS

Neurobiology of schizophrenia: from outcome to pathophysiological insights

(2012) P. Falkai et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer

(2012) M. Delwar Hussain et al.   International Journal of Nanomedicine

Exploratory Analyses of Efficacy Data From Schizophrenia Trials in Support of New Drug Applications Submitted to the US Food and Drug Administration

(2012) Ni A. Khin et al.   JOURNAL OF CLINICAL PSYCHIATRY

Delivery of P-glycoprotein substrates using chemosensitizers and nanotechnology for selective and efficient therapeutic outcomes

(2012) Rita Nieto Montesinos et al.   JOURNAL OF CONTROLLED RELEASE

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier

(2012) Ana Beloqui et al.   JOURNAL OF CONTROLLED RELEASE

Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds

(2012) Stephen A. Hitchcock   JOURNAL OF MEDICINAL CHEMISTRY

Core–shell-type lipid–polymer hybrid nanoparticles as a drug delivery platform

(2012) Bivash Mandal et al.   Nanomedicine-Nanotechnology Biology and Medicine

Nanotechnological advances for the delivery of CNS therapeutics

(2011) Ho Lun Wong et al.   ADVANCED DRUG DELIVERY REVIEWS

Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance

(2011) Feihu Wang et al.   BIOMATERIALS

The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles

(2011) Ran Mo et al.   BIOMATERIALS

Design and engineering of nanogels for cancer treatment

(2011) Murali Mohan Yallapu et al.   DRUG DISCOVERY TODAY

Microvesicles and exosomes: Opportunities for cell-derived membrane vesicles in drug delivery

(2011) Susan M. van Dommelen et al.   JOURNAL OF CONTROLLED RELEASE

Influence of intestinal efflux pumps on the absorption and transport of furosemide

(2011) Abdullah M. Al-Mohizea   SAUDI PHARMACEUTICAL JOURNAL

Transferrin-conjugated nanoparticles of Poly(lactide)-d-α-Tocopheryl polyethylene glycol succinate diblock copolymer for targeted drug delivery across the blood–brain barrier

(2010) Chee Wee Gan et al.   BIOMATERIALS

Reciprocal competition between lipid nanocapsules and P-gp for paclitaxel transport across Caco-2 cells

(2010) E. Roger et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Excipients enhance intestinal absorption of ganciclovir by P-gp inhibition: Assessed in vitro by everted gut sac and in situ by improved intestinal perfusion

(2010) Ming Li et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor

(2010) Javed Iqbal et al.   JOURNAL OF CONTROLLED RELEASE

Schizophrenia and Borderline Personality Disorder

(2010) David G. Kingdon et al.   JOURNAL OF NERVOUS AND MENTAL DISEASE

Rethinking schizophrenia

(2010) Thomas R. Insel   NATURE

The environment and schizophrenia

(2010) Jim van Os et al.   NATURE

Regional increase in P-glycoprotein function in the blood-brain barrier of patients with chronic schizophrenia:

(2010) Onno L. de Klerk et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Nanoparticles as Novel Carrier for Brain Delivery: A Review

(2009) Abhinav Agarwal et al.   CURRENT PHARMACEUTICAL DESIGN

Novel formulation approaches for optimising delivery of anticancer drugs based on P-glycoprotein modulation

(2009) Tripta Bansal et al.   DRUG DISCOVERY TODAY

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

(2009) Reinhard Gabathuler   NEUROBIOLOGY OF DISEASE

Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: Effects of the novel P-glycoprotein inhibitor tariquidar

(2009) Christian la Fougère et al.   NEUROIMAGE

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

(2009) Pär Matsson et al.   PHARMACEUTICAL RESEARCH

Aripiprazole brain concentration is altered in P-glycoprotein deficient mice

(2009) Jun-Sheng Wang et al.   SCHIZOPHRENIA RESEARCH

Schizophrenia, “just the facts” 4. Clinical features and conceptualization

(2009) Rajiv Tandon et al.   SCHIZOPHRENIA RESEARCH

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

(2009) S. G. Aller et al.   SCIENCE

Poly (D, L-Lactide) Nanosuspensions of Risperidone for Parenteral Delivery: Formulation and In-Vitro Evaluation

(2009) M. Muthu et al.   Current Drug Delivery

Differential pharmacological regulation of drug efflux and pharmacoresistant schizophrenia

(2008) Mary Bebawy et al.   BIOESSAYS

Dendrimers as versatile platform in drug delivery applications

(2008) Sonke Svenson   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain

(2008) Derek J Roberts et al.   Expert Opinion on Drug Metabolism & Toxicology

Potential of solid lipid nanoparticles in brain targeting

(2008) Indu Pal Kaur et al.   JOURNAL OF CONTROLLED RELEASE

Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug

(2008) Taher Nassar et al.   JOURNAL OF CONTROLLED RELEASE

Decreased blood–brain barrier P-glycoprotein function in the progression of Parkinson’s disease, PSP and MSA

(2008) A. L. Bartels et al.   JOURNAL OF NEURAL TRANSMISSION

Thiolated chitosans: useful excipients for oral drug delivery

(2008) Martin Werle et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Intestinal Breast Cancer Resistance Protein (BCRP)/Bcrp1 and Multidrug Resistance Protein 3 (MRP3)/Mrp3 Are Involved in the Pharmacokinetics of Resveratrol

(2008) K. van de Wetering et al.   MOLECULAR PHARMACOLOGY

Blood–brain barrier P-glycoprotein function decreases in specific brain regions with aging: A possible role in progressive neurodegeneration

(2008) Anna L. Bartels et al.   NEUROBIOLOGY OF AGING

Review: Role of developmental inflammation and blood-brain barrier dysfunction in neurodevelopmental and neurodegenerative diseases

(2008) H. B. Stolp et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Modulation of P-Glycoprotein at the Blood-Brain Barrier: Opportunities to Improve Central Nervous System Pharmacotherapy

(2008) D. S. Miller et al.   PHARMACOLOGICAL REVIEWS

Pharmacodynamic consequences of P-glycoprotein-dependent pharmacokinetics of risperidone and haloperidol in mice

(2007) K KIRSCHBAUM   BEHAVIOURAL BRAIN RESEARCH