Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Computational Study of Correlated Domain Motions in the AcrB Efflux Transporter
Authors
Keywords
-
Journal
Biomed Research International
Volume 2015, Issue -, Pages 1-12
Publisher
Hindawi Limited
Online
2015-01-06
DOI
10.1155/2015/487298
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- TRANSLOCATION Project: How to Get Good Drugs into Bad Bugs
- (2014) R. A. Stavenger et al. Science Translational Medicine
- Efflux pump-mediated antibiotics resistance: Insights from computational structural biology
- (2014) Nadine Fischer et al. Interdisciplinary Sciences-Computational Life Sciences
- RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
- (2013) Paolo Ruggerone et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Locked on One Side Only: Ground State Dynamics of the Outer Membrane Efflux Duct TolC
- (2012) Martin Raunest et al. BIOCHEMISTRY
- Porter domain opening and closing motions in the multi-drug efflux transporter AcrB
- (2012) Nadine Fischer et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Antibiotics: A New Hope
- (2012) Gerard D. Wright CHEMISTRY & BIOLOGY
- Adaptive and Mutational Resistance: Role of Porins and Efflux Pumps in Drug Resistance
- (2012) L. Fernandez et al. CLINICAL MICROBIOLOGY REVIEWS
- Losing ground
- (2012) Ramin S. Herati et al. CURRENT OPINION IN INFECTIOUS DISEASES
- Understanding efflux in Gram-negative bacteria: opportunities for drug discovery
- (2012) Herbert P Schweizer Expert Opinion on Drug Discovery
- Assembling of AcrB Trimer in Cell Membrane
- (2012) Wei Lu et al. JOURNAL OF MOLECULAR BIOLOGY
- Interdomain Flexibility and pH-Induced Conformational Changes of AcrA Revealed by Molecular Dynamics Simulations
- (2012) Beibei Wang et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Analysis and Elimination of a Bias in Targeted Molecular Dynamics Simulations of Conformational Transitions: Application to Calmodulin
- (2012) Victor Ovchinnikov et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Recognition of Imipenem and Meropenem by the RND-Transporter MexB Studied by Computer Simulations
- (2012) Francesca Collu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Inter-domain movements in polyketide synthases: a molecular dynamics study
- (2012) Swadha Anand et al. Molecular BioSystems
- The Conformational Transition Pathways of ATP-Binding Cassette Transporter BtuCD Revealed by Targeted Molecular Dynamics Simulation
- (2012) Jingwei Weng et al. PLoS One
- Multidrug binding properties of the AcrB efflux pump characterized by molecular dynamics simulations
- (2012) A. V. Vargiu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
- (2012) T. Eicher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- GDP Release Preferentially Occurs on the Phosphate Side in Heterotrimeric G-proteins
- (2012) Maxime Louet et al. PLoS Computational Biology
- Sequential Mechanism of Assembly of Multidrug Efflux Pump AcrAB-TolC
- (2011) Elena B. Tikhonova et al. CHEMISTRY & BIOLOGY
- Role of Water during the Extrusion of Substrates by the Efflux Transporter AcrB
- (2011) Robert Schulz et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Effect of the F610A Mutation on Substrate Extrusion in the AcrB Transporter: Explanation and Rationale by Molecular Dynamics Simulations
- (2011) Attilio V. Vargiu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
- (2011) Ryosuke Nakashima et al. NATURE
- Elastic network model-based normal mode analysis reveals the conformational couplings in the tripartite AcrAB-TolC multidrug efflux complex
- (2011) Beibei Wang et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Three ways in, one way out: Water dynamics in the trans-membrane domains of the inner membrane translocase AcrB
- (2011) Nadine Fischer et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations
- (2010) Robert Schulz et al. PLoS Computational Biology
- Multidrug Resistance in Bacteria
- (2009) Hiroshi Nikaido Annual Review of Biochemistry
- Assembly and transport mechanism of tripartite drug efflux systems
- (2009) Rajeev Misra et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Transitions between Closed and Open Conformations of TolC: The Effects of Ions in Simulations
- (2009) Robert Schulz et al. BIOPHYSICAL JOURNAL
- Comparison of Three Perturbation Molecular Dynamics Methods for Modeling Conformational Transitions
- (2009) He Huang et al. Journal of Chemical Theory and Computation
- A coordinated network of transporters with overlapping specificities provides a robust survival strategy
- (2009) N. Tal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The assembled structure of a complete tripartite bacterial multidrug efflux pump
- (2009) M. F. Symmons et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The AcrB Efflux Pump: Conformational Cycling and Peristalsis Lead to Multidrug Resistance
- (2008) Markus Seeger et al. CURRENT DRUG TARGETS
- Physical Insights into Permeation of and Resistance to Antibiotics in Bacteria
- (2008) Matteo Ceccarelli et al. CURRENT DRUG TARGETS
- GROMACS 4: Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation
- (2008) Berk Hess et al. Journal of Chemical Theory and Computation
- Assembly and Channel Opening in a Bacterial Drug Efflux Machine
- (2008) Vassiliy N. Bavro et al. MOLECULAR CELL
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started