Towards a phenome-wide catalog of human clinical traits impacted by genetic ancestry

Leveraging Epidemiologic and Clinical Collections for Genomic Studies of Complex Traits

(2015) Dana C. Crawford et al.   HUMAN HEREDITY

Genetic Determinants of P Wave Duration and PR Segment

(2014) N. Verweij et al.   Circulation-Cardiovascular Genetics

Evidence of Heterogeneity by Race/Ethnicity in Genetic Determinants of QT Interval

(2014) Amanda A. Seyerle et al.   EPIDEMIOLOGY

Accuracy of Administratively-Assigned Ancestry for Diverse Populations in an Electronic Medical Record-Linked Biobank

(2014) Jacob B. Hall et al.   PLoS One

Phenome-wide association studies demonstrating pleiotropy of genetic variants within FTO with and without adjustment for body mass index

(2014) Robert M. Cronin et al.   Frontiers in Genetics

African American race but not genome-wide ancestry is negatively associated with atrial fibrillation among postmenopausal women in the Women's Health Initiative

(2013) Marco V. Perez et al.   AMERICAN HEART JOURNAL

Generalization of Variants Identified by Genome-Wide Association Studies for Electrocardiographic Traits in African Americans

(2013) Janina M. Jeff et al.   ANNALS OF HUMAN GENETICS

Genome- and Phenome-Wide Analyses of Cardiac Conduction Identifies Markers of Arrhythmia Risk

(2013) Marylyn D. Ritchie et al.   CIRCULATION

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Impact of Ancestry and Common Genetic Variants on QT Interval in African Americans

(2012) J. Gustav Smith et al.   Circulation-Cardiovascular Genetics

Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

(2012) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Characterization of Genome-Wide Association-Identified Variants for Atrial Fibrillation in African Americans

(2012) Jessica T. Delaney et al.   PLoS One

Evaluation of the Metabochip Genotyping Array in African Americans and Implications for Fine Mapping of GWAS-Identified Loci: The PAGE Study

(2012) Steven Buyske et al.   PLoS One

Fine-Mapping and Initial Characterization of QT Interval Loci in African Americans

(2012) Christy L. Avery et al.   PLoS Genetics

The Metabochip, a Custom Genotyping Array for Genetic Studies of Metabolic, Cardiovascular, and Anthropometric Traits

(2012) Benjamin F. Voight et al.   PLoS Genetics

The Next PAGE in Understanding Complex Traits: Design for the Analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study

(2011) Tara C. Matise et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

(2011) S.A. Pendergrass et al.   GENETIC EPIDEMIOLOGY

Use of diverse electronic medical record systems to identify genetic risk for type 2 diabetes within a genome-wide association study

(2011) Abel N Kho et al.   JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION

Genome-Wide Association Studies of the PR Interval in African Americans

(2011) J. Gustav Smith et al.   PLoS Genetics

PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations

(2010) J. C. Denny et al.   BIOINFORMATICS

European Ancestry as a Risk Factor for Atrial Fibrillation in African Americans

(2010) Gregory M. Marcus et al.   CIRCULATION

Principles of Human Subjects Protections Applied in an Opt-Out, De-identified Biobank

(2010) Jill Pulley et al.   CTS-Clinical and Translational Science

Assessing the accuracy of observer-reported ancestry in a biorepository linked to electronic medical records

(2010) Logan Dumitrescu et al.   GENETICS IN MEDICINE

Modulators of normal electrocardiographic intervals identified in a large electronic medical record

(2010) Andrea H. Ramirez et al.   HEART RHYTHM

US Trends in Prevalence, Awareness, Treatment, and Control of Hypertension, 1988-2008

(2010) Brent M. Egan   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

(2010) Nona Sotoodehnia et al.   NATURE GENETICS

Genetic variation in SCN10A influences cardiac conduction

(2010) John C Chambers et al.   NATURE GENETICS

Inference of locus-specific ancestry in closely related populations

(2009) B. Pasaniuc et al.   BIOINFORMATICS

Common variants at ten loci modulate the QT interval duration in the QTSCD Study

(2009) Arne Pfeufer et al.   NATURE GENETICS

Common variants at ten loci influence QT interval duration in the QTGEN Study

(2009) Christopher Newton-Cheh et al.   NATURE GENETICS

Development of a Large-Scale De-Identified DNA Biobank to Enable Personalized Medicine

(2008) DM Roden et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS