The sweet side of RNA regulation: glyceraldehyde-3-phosphate dehydrogenase as a noncanonical RNA-binding protein

A novel variant in the 3′ UTR of human SCN1A gene from a patient with Dravet syndrome decreases mRNA stability mediated by GAPDH’s binding

(2014) Tao Zeng et al.   HUMAN GENETICS

Structural analysis of glyceraldehyde-3-phosphate dehydrogenase functional diversity

(2014) Michael A. Sirover   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Structural insights into RNA recognition properties of glyceraldehyde-3-phosphate dehydrogenase 3 fromSaccharomyces cerevisiae

(2014) Hui Shen et al.   IUBMB LIFE

A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA

(2014) Michael R. White et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxidation of an Exposed Methionine Instigates the Aggregation of Glyceraldehyde-3-phosphate Dehydrogenase

(2014) Andre L. Samson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Photo-cross-linking and high-resolution mass spectrometry for assignment of RNA-binding sites in RNA-binding proteins

(2014) Katharina Kramer et al.   NATURE METHODS

High-resolution crystal structures of the photoreceptor glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with three and four-bound NAD molecules

(2014) Bo Y. Baker et al.   PROTEIN SCIENCE

PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity

(2014) Je-Hyun Yoon et al.   Nature Communications

Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis

(2013) Chih-Hao Chang et al.   CELL

NleB, a Bacterial Effector with Glycosyltransferase Activity, Targets GAPDH Function to Inhibit NF-κB Activation

(2013) Xiaofei Gao et al.   Cell Host & Microbe

Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) Phosphorylation by Protein Kinase Cδ (PKCδ) Inhibits Mitochondria Elimination by Lysosomal-like Structures following Ischemia and Reoxygenation-induced Injury

(2013) Gouri Yogalingam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nucleolin Mediates MicroRNA-directed CSF-1 mRNA Deadenylation but Increases Translation of CSF-1 mRNA

(2013) Ho-Hyung Woo et al.   MOLECULAR & CELLULAR PROTEOMICS

Metabolite sensing in eukaryotic mRNA biology

(2013) Carina C. Clingman et al.   Wiley Interdisciplinary Reviews-RNA

Glyceraldehyde-3-phosphate dehydrogenase regulates cyclooxygenase-2 expression by targeting mRNA stability

(2012) Yuki Ikeda et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Heme Binding Properties of Glyceraldehyde-3-phosphate Dehydrogenase

(2012) Luciana Hannibal et al.   BIOCHEMISTRY

Post-transcriptional control of gene expression by AUF1: Mechanisms, physiological targets, and regulation

(2012) Elizabeth J.F. White et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Subcellular dynamics of multifunctional protein regulation: Mechanisms of GAPDH intracellular translocation

(2012) Michael A. Sirover   JOURNAL OF CELLULAR BIOCHEMISTRY

SCN1A Mutation Associated With Intractable Myoclonic Epilepsy and Migraine Headache

(2012) Patrick Frosk et al.   JOURNAL OF CHILD NEUROLOGY

Hsp70 Is a Novel Posttranscriptional Regulator of Gene Expression That Binds and Stabilizes Selected mRNAs Containing AU-Rich Elements

(2012) A. Kishor et al.   MOLECULAR AND CELLULAR BIOLOGY

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA component

(2012) C. Nicholls et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insight into RNA recognition motifs: versatile molecular Lego building blocks for biological systems

(2012) Yutaka Muto et al.   Wiley Interdisciplinary Reviews-RNA

Perspectives on the ARE as it turns 25 years old

(2012) Daniel Beisang et al.   Wiley Interdisciplinary Reviews-RNA

Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA

(2011) Seiji Kondo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS

(2011) Apirat Chaikuad et al.   BIOCHEMICAL JOURNAL

On the functional diversity of glyceraldehyde-3-phosphate dehydrogenase: Biochemical mechanisms and regulatory control

(2011) Michael A. Sirover   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

GAPDH: A common enzyme with uncommon functions

(2011) Craig Nicholls et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Akt2 Kinase Suppresses Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH)-mediated Apoptosis in Ovarian Cancer Cells via Phosphorylating GAPDH at Threonine 237 and Decreasing Its Nuclear Translocation

(2011) Qiaojia Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glyceraldehyde 3-Phosphate Dehydrogenase Negatively Regulates the Replication of Bamboo Mosaic Virus and Its Associated Satellite RNA

(2011) K. R. Prasanth et al.   JOURNAL OF VIROLOGY

Direct Inhibition of Tombusvirus Plus-Strand RNA Synthesis by a Dominant Negative Mutant of a Host Metabolic Enzyme, Glyceraldehyde-3-Phosphate Dehydrogenase, in Yeast and Plants

(2011) T.-S. Huang et al.   JOURNAL OF VIROLOGY

PAPD5, a noncanonical poly(A) polymerase with an unusual RNA-binding motif

(2011) C. Rammelt et al.   RNA

The diverse functions of GAPDH: Views from different subcellular compartments

(2010) Carlos Tristan et al.   CELLULAR SIGNALLING

Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase is regulated by acetylation

(2010) Mireia Ventura et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

GAPDH regulates cellular heme insertion into inducible nitric oxide synthase

(2010) R. Chakravarti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The REM phase of gene regulation

(2010) Matthias W. Hentze et al.   TRENDS IN BIOCHEMICAL SCIENCES

The role of AUF1 in regulated mRNA decay

(2010) Frances M. Gratacós et al.   Wiley Interdisciplinary Reviews-RNA

Potential Role of Endothelin-1 in Pulmonary Fibrosis

(2009) Bryan Ross et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Glyceraldehyde-3-phosphate Dehydrogenase Aggregate Formation Participates in Oxidative Stress-induced Cell Death

(2009) Hidemitsu Nakajima et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Binding of Glyceraldehyde 3-Phosphate Dehydrogenase to Telomeric DNA Protects Telomeres against Chemotherapy-Induced Rapid Degradation

(2009) Neil A. Demarse et al.   JOURNAL OF MOLECULAR BIOLOGY

Glycolytic Flux Signals to mTOR through Glyceraldehyde-3-Phosphate Dehydrogenase-Mediated Regulation of Rheb

(2009) M. N. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

UTRdb and UTRsite (RELEASE 2010): a collection of sequences and regulatory motifs of the untranslated regions of eukaryotic mRNAs

(2009) Giorgio Grillo et al.   NUCLEIC ACIDS RESEARCH

Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenase

(2009) M. Backlund et al.   NUCLEIC ACIDS RESEARCH

Host cell proteins interacting with the 3′ end of TGEV coronavirus genome influence virus replication

(2009) Carmen Galán et al.   VIROLOGY

O-GlcNAcylation disrupts glyceraldehyde-3-phosphate dehydrogenase homo-tetramer formation and mediates its nuclear translocation

(2008) Jungeun Park et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Tomato bushy stunt virus Co-Opts the RNA-Binding Function of a Host Metabolic Enzyme for Viral Genomic RNA Synthesis

(2008) Robert Yung-Liang Wang et al.   Cell Host & Microbe

Human Glyceraldehyde-3-phosphate Dehydrogenase Plays a Direct Role in Reactivating Oxidized Forms of the DNA Repair Enzyme APE1

(2008) Sonish Azam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Strategy for Comprehensive Identification of Post-translational Modifications in Cellular Proteins, Including Low Abundant Modifications: Application to Glyceraldehyde-3-phosphate Dehydrogenase

(2008) Jawon Seo et al.   JOURNAL OF PROTEOME RESEARCH

Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Endothelin-1 Expression by a Novel, Redox-Sensitive Mechanism Involving mRNA Stability

(2008) F. Rodriguez-Pascual et al.   MOLECULAR AND CELLULAR BIOLOGY

The Multifunctional Protein Glyceraldehyde-3-Phosphate Dehydrogenase Is Both Regulated and Controls Colony-Stimulating Factor-1 Messenger RNA Stability in Ovarian Cancer

(2008) Y. Zhou et al.   MOLECULAR CANCER RESEARCH

Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosis

(2008) Nilkantha Sen et al.   NATURE CELL BIOLOGY