Critical Early Thrombolytic and Endovascular Reperfusion Therapy for Acute Ischemic Stroke Victims: a Call for Adjunct Neuroprotection

Why don’t more patients receive intravenous rt-PA for acute stroke?

(2015) Patrick Lyden   Expert Review of Neurotherapeutics

Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) Trial: Protocol for a Randomized, Controlled, Multicenter Study Comparing the Solitaire Revascularization Device with IV tPA with IV tPA Alone in Acute Ischemic Stroke

(2015) Jeffrey L. Saver et al.   International Journal of Stroke

Focal embolic cerebral ischemia in the rat

(2015) Li Zhang et al.   Nature Protocols

Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke

(2015) Tudor G. Jovin et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

(2015) Olvert A. Berkhemer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cost-Effectiveness of Intra-Arterial Treatment as an Adjunct to Intravenous Tissue-Type Plasminogen Activator for Acute Ischemic Stroke

(2015) Michelle H. Leppert et al.   STROKE

A Cost-Effective Rabbit Embolic Stroke Bioassay: Insight into the Development of Acute Ischemic Stroke Therapy

(2015) Paul A. Lapchak   Translational Stroke Research

Why don’t more patients receive intravenous rt-PA for acute stroke?

(2015) Patrick Lyden   Expert Review of Neurotherapeutics

Drill down analysis of door-to-needle time of acute ischemic stroke patients treated with intravenous tissue plasminogen activator

(2014) Jon W. Schrock et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Time Is Penumbra: Imaging, Selection and Outcome

(2014) Stephen Davis et al.   CEREBROVASCULAR DISEASES

Italian guidelines on thrombolysis indications in ischemic stroke have been revised after the IST-3 trial and Cochrane review

(2014) Maurizio Paciaroni   Internal and Emergency Medicine

Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials

(2014) Jonathan Emberson et al.   LANCET

A comparison of rt-PA thrombolysis guidelines between China and the USA: are changes needed?

(2014) Jing Xu et al.   NEUROLOGICAL RESEARCH

Cost-Effectiveness of Recombinant Tissue-Type Plasminogen Activator Within 3 Hours of Acute Ischemic Stroke

(2014) Denise M. Boudreau et al.   STROKE

Transcranial Laser Therapy in Acute Stroke Treatment

(2014) Werner Hacke et al.   STROKE

Adherence to Third European Cooperative Acute Stroke Study 3- to 4.5-Hour Exclusions and Association With Outcome

(2014) Carolyn A. Cronin et al.   STROKE

MR CLEAN, a multicenter randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomized controlled trial

(2014) Puck SS Fransen et al.   Trials

Glycemic Variability and Acute Ischemic Stroke: The Missing Link?

(2014) Emmanuel I. González-Moreno et al.   Translational Stroke Research

Remote Ischemic Perconditioning is Effective After Embolic Stroke in Ovariectomized Female Mice

(2014) Md Nasrul Hoda et al.   Translational Stroke Research

Hyperglycemia, Acute Ischemic Stroke, and Thrombolytic Therapy

(2014) Sherif Hafez et al.   Translational Stroke Research

Hyperglycemia Worsens Outcome After rt-PA Primarily in the Large-Vessel Occlusive Stroke Subtype

(2014) Pitchaiah Mandava et al.   Translational Stroke Research

Temporal Trends in Patient Characteristics and Treatment With Intravenous Thrombolysis Among Acute Ischemic Stroke Patients at Get With the Guidelines–Stroke Hospitals

(2013) Lee H. Schwamm et al.  

Prenotification and Other Factors Involved in Rapid tPA Administration

(2013) Jamsheed A. Desai et al.   Current Atherosclerosis Reports

Time to Treatment With Intravenous Tissue Plasminogen Activator and Outcome From Acute Ischemic Stroke

(2013) Jeffrey L. Saver et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Endovascular Treatment for Acute Ischemic Stroke

(2013) Alfonso Ciccone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke

(2013) Joseph P. Broderick et al.   NEW ENGLAND JOURNAL OF MEDICINE

Recommendations and Practices to Optimize Stroke Therapy

(2013) Paul A. Lapchak   STROKE

Guidelines for the Early Management of Patients With Acute Ischemic Stroke

(2013) Edward C. Jauch et al.   STROKE

Fast Neuroprotection (Fast-NPRX) for Acute Ischemic Stroke Victims: the Time for Treatment Is Now

(2013) Paul A. Lapchak   Translational Stroke Research

A Model of Cost-effectiveness of Tissue Plasminogen Activator in Patient Subgroups 3 to 4.5 Hours After Onset of Acute Ischemic Stroke

(2012) Denise M. Boudreau et al.   ANNALS OF EMERGENCY MEDICINE

Design and Rationale of the Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE) Trial

(2012) Chelsea S. Kidwell et al.   International Journal of Stroke

The Two Pathophysiologies of Focal Brain Ischemia: Implications for Translational Stroke Research

(2012) Konstantin-Alexander Hossmann   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Treatment of stroke with a PSD-95 inhibitor in the gyrencephalic primate brain

(2012) Douglas J. Cook et al.   NATURE

Cost-effectiveness of endovascular therapy for acute ischemic stroke

(2012) M. Chen   NEUROLOGY

Nonhuman Primate Models of Stroke for Translational Neuroprotection Research

(2012) Douglas J. Cook et al.   Neurotherapeutics

Sisyphus and Translational Stroke Research

(2012) P. Lyden et al.   Science Translational Medicine

RIGOR Guidelines: Escalating STAIR and STEPS for Effective Translational Research

(2012) Paul A. Lapchak et al.   Translational Stroke Research

Timeliness of Tissue-Type Plasminogen Activator Therapy in Acute Ischemic Stroke

(2011) Gregg C. Fonarow et al.   CIRCULATION

A Qualitative Assessment of Practices Associated With Shorter Door-to-Needle Time for Thrombolytic Therapy in Acute Ischemic Stroke

(2011) DaiWai M. Olson et al.   JOURNAL OF NEUROSCIENCE NURSING

Improving Door-to-Needle Times in Acute Ischemic Stroke

(2011) Gregg C. Fonarow et al.   STROKE

Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited

(2011) Peter Sandercock et al.   Trials

Are Underlying Assumptions of Current Animal Models of Human Stroke Correct: from STAIRs to High Hurdles?

(2011) Renée J. Turner et al.   Translational Stroke Research

Trends in thrombolytic use for ischemic stroke in the United States

(2010) Margaret C. Fang et al.   Journal of Hospital Medicine

The “Golden Hour” and Acute Brain Ischemia

(2010) Jeffrey L. Saver et al.   STROKE

Translational Stroke Research Using a Rabbit Embolic Stroke Model: A Correlative Analysis Hypothesis for Novel Therapy Development

(2010) Paul A. Lapchak   Translational Stroke Research

Stroke treatment with alteplase given 3·0–4·5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial

(2009) Erich Bluhmki et al.   LANCET NEUROLOGY

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rabbit Subselective Angiography Stroke Model

(2008) Benjamin C. Culp et al.   STROKE