New Concepts of Immune Modulation in Xenotransplantation

Galactosyl-knock-out engineered pig as a xenogenic donor source of adipose MSCs for bone regeneration

(2013) Thomas Schubert et al.   BIOMATERIALS

Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status

(2013) Hidetaka Hara et al.   IMMUNOLOGY

Potential of T-regulatory cells to protect xenografts

(2012) Yannick D. Muller et al.   Current Opinion in Organ Transplantation

Adipose-derived mesenchymal stromal cells from genetically modified pigs: immunogenicity and immune modulatory properties

(2012) Goutham Kumar et al.   CYTOTHERAPY

Immunobiology of liver xenotransplantation

(2012) Burcin Ekser et al.   Expert Review of Clinical Immunology

Rethinking inflammation: neural circuits in the regulation of immunity

(2012) Peder S. Olofsson et al.   IMMUNOLOGICAL REVIEWS

Treatment of hyperacute antibody-mediated lung allograft rejection with eculizumab

(2012) Kyle L. Dawson et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Impact of intensive statin use on the level of inflammation and platelet activation in stable angina after percutaneous coronary intervention: A clinical study

(2012) Qing Li et al.   MEDICINA CLINICA

Human CD55 Expression Blocks Hyperacute Rejection and Restricts Complement Activation in Gal Knockout Cardiac Xenografts

(2012) Christopher G.A. McGregor et al.   TRANSPLANTATION

Human T-cell proliferation in response to thrombin-activated GTKO pig endothelial cells

(2012) Corin Ezzelarab et al.   XENOTRANSPLANTATION

T-cell-mediated immunological barriers to xenotransplantation

(2012) Joseph Scalea et al.   XENOTRANSPLANTATION

Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantation

(2012) Jiang Li et al.   XENOTRANSPLANTATION

The effect of Gal expression on pig cells on the human T-cell xenoresponse

(2012) Tyler Wilhite et al.   XENOTRANSPLANTATION

B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months

(2011) M. M. Mohiuddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Therapeutic issues in the treatment of vascularized xenotransplants using gal-knockout donors in nonhuman primates

(2011) Burcin Ekser et al.   Current Opinion in Organ Transplantation

Controlling coagulation dysregulation in xenotransplantation

(2011) Peter J Cowan et al.   Current Opinion in Organ Transplantation

Intracerebral xenotransplantation: recent findings and perspectives for local immunosuppression

(2011) Xavier Lévêque et al.   Current Opinion in Organ Transplantation

Relative efficiency of porcine and human cytotoxic T-lymphocyte antigen 4 immunoglobulin in inhibiting human CD4+ T-cell responses co-stimulated by porcine and human B7 molecules

(2011) Tadatsura Koshika et al.   IMMUNOLOGY

Human PD-L1-overexpressing porcine vascular endothelial cells induce functionally suppressive human CD4+CD25hiFoxp3+ Treg cells

(2011) Q. Ding et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate immunity and coagulation

(2011) C. T. ESMON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Genetically-modified pig mesenchymal stromal cells: xenoantigenicity and effect on human T-cell xenoresponses

(2011) Mohamed Ezzelarab et al.   XENOTRANSPLANTATION

Transgenic expression of human heme oxygenase-1 in pigs confers resistance against xenograft rejection during ex vivo perfusion of porcine kidneys

(2011) Björn Petersen et al.   XENOTRANSPLANTATION

Recipient Tissue Factor Expression Is Associated With Consumptive Coagulopathy in Pig-to-Primate Kidney Xenotransplantation

(2010) C. C. Lin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Role of regulatory T cells in xenotransplantation

(2010) Philip J OʼConnell et al.   Current Opinion in Organ Transplantation

Anti-CD154 mAb and Rapamycin Induce T Regulatory Cell Mediated Tolerance in Rat-to-Mouse Islet Transplantation

(2010) Yannick D. Muller et al.   PLoS One

Surgical and Nonsurgical Complications of a Pig to Baboon Heterotopic Heart Transplantation Model

(2010) P.C. Corcoran et al.   TRANSPLANTATION PROCEEDINGS

Results of Gal-Knockout Porcine Thymokidney Xenografts

(2009) A. D. Griesemer et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Renal and Cardiac Endothelial Heterogeneity Impact Acute Vascular Rejection in Pig-to-Baboon Xenotransplantation

(2009) C. Knosalla et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Innate Immune Response and Activation of Coagulation in α1,3-Galactosyltransferase Gene-Knockout Xenograft Recipients

(2009) Mohamed Ezzelarab et al.   TRANSPLANTATION

HLA-E/Human β2-Microglobulin Transgenic Pigs: Protection Against Xenogeneic Human Anti-Pig Natural Killer Cell Cytotoxicity

(2009) Elisabeth H. Weiss et al.   TRANSPLANTATION

Suppression of Human T-Cell Activation and Expansion of Regulatory T Cells by Pig Cells Overexpressing PD-Ligands

(2009) Annegret Plege et al.   TRANSPLANTATION

Transgenic expression of the human A20 gene in cloned pigs provides protection against apoptotic and inflammatory stimuli

(2009) Marianne Oropeza et al.   XENOTRANSPLANTATION

Production and characterization of transgenic pigs expressing porcine CTLA4-Ig

(2009) Carol J. Phelps et al.   XENOTRANSPLANTATION

Current status of xenotransplantation and prospects for clinical application

(2009) Richard N. Pierson et al.   XENOTRANSPLANTATION

The Use of Antibody to Complement Protein C5 for Salvage Treatment of Severe Antibody-Mediated Rejection

(2008) J. E. Locke et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Expression of Tissue Factor and Initiation of Clotting by Human Platelets and Monocytes After Incubation With Porcine Endothelial Cells

(2008) Chih Che Lin et al.   TRANSPLANTATION

Atorvastatin Down-Regulates the Primate Cellular Response to Porcine Aortic Endothelial Cells In Vitro

(2008) Mohamed Ezzelarab et al.   TRANSPLANTATION

Suppressive Efficacy and Proliferative Capacity of Human Regulatory T Cells in Allogeneic and Xenogeneic Responses

(2008) Yih-Jyh Lin et al.   TRANSPLANTATION