Digoxin Attenuates Acute Cardiac Allograft Rejection by Antagonizing RORγt Activity

IL-17 Expression by Tubular Epithelial Cells in Renal Transplant Recipients with Acute Antibody-Mediated Rejection

(2011) A. Loverre et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Loss of Myeloid Related Protein-8/14 Exacerbates Cardiac Allograft Rejection

(2011) Koichi Shimizu et al.   CIRCULATION

Interleukin-17 Accelerates Allograft Rejection by Suppressing Regulatory T Cell Expansion

(2011) S. Itoh et al.   CIRCULATION

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Structural Basis of Digoxin That Antagonizes RORγt Receptor Activity and Suppresses Th17 Cell Differentiation and Interleukin (IL)-17 Production

(2011) Saori Fujita-Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Digoxin and its derivatives suppress TH17 cell differentiation by antagonizing RORγt activity

(2011) Jun R. Huh et al.   NATURE

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

(2011) Laura Codarri et al.   NATURE IMMUNOLOGY

ROR blockers inhibit TH17 cells

(2011) Iley Ozerlat   Nature Reviews Neurology

Interleukin-17 Promotes Early Allograft Inflammation

(2010) Victoria Gorbacheva et al.   AMERICAN JOURNAL OF PATHOLOGY

Dynamic changes in Th1, Th17, and FoxP3+ T cells in patients with acute cellular rejection after cardiac transplantation

(2010) Sihua Wang et al.   CLINICAL TRANSPLANTATION

The impact of Th17 cells on transplant rejection and the induction of tolerance

(2010) Sebastiaan Heidt et al.   Current Opinion in Organ Transplantation

IL-17 Contributes to the Development of Chronic Rejection in a Murine Heart Transplant Model

(2010) Satoshi Itoh et al.   JOURNAL OF CLINICAL IMMUNOLOGY

RORC2 Is Involved in T Cell Polarization through Interaction with the FOXP3 Promoter

(2010) S. Burgler et al.   JOURNAL OF IMMUNOLOGY

IL-1 -Mediated Signals Preferentially Drive Conversion of Regulatory T Cells but Not Conventional T Cells into IL-17-Producing Cells

(2010) L. Li et al.   JOURNAL OF IMMUNOLOGY

The Th17-Defining Transcription Factor ROR t Promotes Glomerulonephritis

(2010) O. M. Steinmetz et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Treatment With Interleukin-12/23p40 Antibody Attenuates Acute Cardiac Allograft Rejection

(2010) Aini Xie et al.   TRANSPLANTATION

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Translational Mini-Review Series on Th17 Cells: Induction of interleukin-17 production by regulatory T cells

(2009) B. Afzali et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The T helper 17–regulatory T cell axis in transplant rejection and tolerance

(2009) Peter Mitchell et al.   Current Opinion in Organ Transplantation

CCR6 regulates EAE pathogenesis by controlling regulatory CD4+T‐cell recruitment to target tissues

(2009) Ricardo Villares et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-9 as a mediator of Th17-driven inflammatory disease

(2009) Elizabeth C. Nowak et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation

(2009) Emilio Fábrega et al.   LIVER TRANSPLANTATION

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

Induction of Regulatory T Cells and Indefinite Survival of Fully Allogeneic Cardiac Grafts by Ursodeoxycholic Acid in Mice

(2009) Qi Zhang et al.   TRANSPLANTATION

IL-17 contributes to CD4-mediated graft-versus-host disease

(2008) L. W. Kappel et al.   BLOOD

RORγ-Expressing Th17 Cells Induce Murine Chronic Intestinal Inflammation via Redundant Effects of IL-17A and IL-17F

(2008) Moritz Leppkes et al.   GASTROENTEROLOGY

A novel role of CD4 Th17 cells in mediating cardiac allograft rejection and vasculopathy

(2008) Xueli Yuan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection

(2008) Deepak A. Rao et al.   JOURNAL OF EXPERIMENTAL MEDICINE