Intra-Articular Transplantation of Atsttrin-Transduced Mesenchymal Stem Cells Ameliorate Osteoarthritis Development

Three TNFR-binding domains of PGRN act independently in inhibition of TNF-alpha binding and activity

(2014) Qingyun Tian   Frontiers in Bioscience-Landmark

Progranulin-Derived Atsttrin Directly Binds to TNFRSF25 (DR3) and Inhibits TNF-Like Ligand 1A (TL1A) Activity

(2014) Cui Liu et al.   PLoS One

Intra-Articular Injection of Mesenchymal Stem Cells for the Treatment of Osteoarthritis of the Knee: A Proof-of-Concept Clinical Trial

(2014) Chris Hyunchul Jo et al.   STEM CELLS

Gene Modification of Mesenchymal Stem Cells and Articular Chondrocytes to Enhance Chondrogenesis

(2014) Saliya Gurusinghe et al.   Biomed Research International

Progranulin deficiency exaggerates, whereas progranulin-derived Atsttrin attenuates, severity of dermatitis in mice

(2013) Yun-Peng Zhao et al.   FEBS LETTERS

Biologic agents in osteoarthritis: hopes and disappointments

(2013) Xavier Chevalier et al.   Nature Reviews Rheumatology

Progranulin antibodies entertain a proinflammatory environment in a subgroup of patients with psoriatic arthritis

(2013) Lorenz Thurner et al.   ARTHRITIS RESEARCH & THERAPY

Neonatal Desensitization Supports Long-Term Survival and Functional Integration of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells in Rat Joint Cartilage Without Immunosuppression

(2012) Shufang Zhang et al.   STEM CELLS AND DEVELOPMENT

Mesenchymal stem cells for cartilage repair in osteoarthritis

(2012) Pawan K Gupta et al.   Stem Cell Research & Therapy

Progranulin: A promising therapeutic target for rheumatoid arthritis

(2011) Chuan-ju Liu   FEBS LETTERS

The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice

(2011) W. Tang et al.   SCIENCE

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Assessment and Optimization of Cell Engraftment After Transplantation Into the Heart

(2010) John V. Terrovitis et al.   CIRCULATION RESEARCH

Certolizumab Pegol

(2010) Niti Goel et al.   mAbs

Direct conversion of fibroblasts to functional neurons by defined factors

(2010) Thomas Vierbuchen et al.   NATURE

Genetic epidemiology of hip and knee osteoarthritis

(2010) Ana M. Valdes et al.   Nature Reviews Rheumatology

Pharmacologic therapy for osteoarthritis—the era of disease modification

(2010) David J. Hunter   Nature Reviews Rheumatology

The bone–cartilage unit in osteoarthritis

(2010) Rik J. Lories et al.   Nature Reviews Rheumatology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Treatment with TNF-α inhibitor infliximab might reduce hand osteoarthritis in patients with rheumatoid arthritis

(2010) M. Güler-Yüksel et al.   OSTEOARTHRITIS AND CARTILAGE

Circulating levels of IL-6 and TNF-α are associated with knee radiographic osteoarthritis and knee cartilage loss in older adults

(2010) O. Stannus et al.   OSTEOARTHRITIS AND CARTILAGE

The OARSI histopathology initiative – recommendations for histological assessments of osteoarthritis in the mouse

(2010) S.S. Glasson et al.   OSTEOARTHRITIS AND CARTILAGE

Design of biomaterials to enhance stem cell survival when transplanted into the damaged central nervous system

(2010) M. J. Cooke et al.   Soft Matter

Migratory Chondrogenic Progenitor Cells from Repair Tissue during the Later Stages of Human Osteoarthritis

(2009) Sebastian Koelling et al.   Cell Stem Cell

Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis

(2009) Shawn P Grogan et al.   ARTHRITIS RESEARCH & THERAPY

Bifunctional enhancement of a β-glucanase-xylanase fusion enzyme by optimization of peptide linkers

(2008) Ping Lu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY