Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation

Multidrug Resistance-Associated Protein 2 (MRP2/ABCC2) Haplotypes Significantly Affect the Pharmacokinetics of Tacrolimus in Kidney Transplant Recipients

(2013) Ken Ogasawara et al.   CLINICAL PHARMACOKINETICS

Population pharmacokinetics of tacrolimus in kidney transplant patients

(2013) R. Velickovic-Radovanovic et al.   INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS

Effects of CYP3A4 and CYP3A5 polymorphisms on tacrolimus pharmacokinetics in Chinese adult renal transplant recipients

(2013) Xiao-cong Zuo et al.   Pharmacogenetics and Genomics

Population Pharmacokinetic Modelling and Design of a Bayesian Estimator for Therapeutic Drug Monitoring of Tacrolimus in Lung Transplantation

(2012) Caroline Monchaud et al.   CLINICAL PHARMACOKINETICS

In Vivo CYP3A4 Activity, CYP3A5 Genotype, and Hematocrit Predict Tacrolimus Dose Requirements and Clearance in Renal Transplant Patients

(2012) H de Jonge et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Prediction of the tacrolimus population pharmacokinetic parameters according to CYP3A5 genotype and clinical factors using NONMEM in adult kidney transplant recipients

(2012) Nayoung Han et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Accurate Detection of Outliers and Subpopulations With Pmetrics, a Nonparametric and Parametric Pharmacometric Modeling and Simulation Package for R

(2012) Michael N. Neely et al.   THERAPEUTIC DRUG MONITORING

Kidney transplant outcomes are related to tacrolimus, mycophenolic acid and prednisolone exposure in the first week

(2012) Katherine A. Barraclough et al.   TRANSPLANT INTERNATIONAL

Dosing equation for tacrolimus using genetic variants and clinical factors

(2011) Chaitali Passey et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A Simultaneous D-Optimal Designed Study for Population Pharmacokinetic Analyses of Mycophenolic Acid and Tacrolimus Early After Renal Transplantation

(2011) Flora Tshinanu Musuamba et al.   JOURNAL OF CLINICAL PHARMACOLOGY

No change in insulin sensitivity in renal transplant recipients converted from standard to once-daily prolonged release tacrolimus

(2011) K. Midtvedt et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Effect of a new functionalCYP3A4polymorphism on calcineurin inhibitors’ dose requirements and trough blood levels in stable renal transplant patients

(2011) Laure Elens et al.   PHARMACOGENOMICS

Population pharmacokinetic model and Bayesian estimator for two tacrolimus formulations - twice daily Prograf® and once daily Advagraf®

(2010) Jean-Baptiste Woillard et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Population Pharmacokinetics and Bayesian Estimation of Tacrolimus Exposure in Renal Transplant Recipients on a New Once-Daily Formulation

(2010) Khaled Benkali et al.   CLINICAL PHARMACOKINETICS

A prospective, open-label, observational clinical cohort study of the association between delayed renal allograft function, tacrolimus exposure, and CYP3A5 genotype in adult recipients

(2010) Dirk R.J. Kuypers et al.   CLINICAL THERAPEUTICS

Association of ABCB1, CYP3A4*18B and CYP3A5*3 genotypes with the pharmacokinetics of tacrolimus in healthy Chinese subjects: a population pharmacokinetic analysis

(2010) X.-J. Shi et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Tacrolimus Population Pharmacokinetic-Pharmacogenetic Analysis and Bayesian Estimation in Renal Transplant Recipients

(2009) Khaled Benkali et al.   CLINICAL PHARMACOKINETICS

Mechanistic Basis of Using Body Size and Maturation to Predict Clearance in Humans

(2009) Brian J. Anderson et al.   Drug Metabolism and Pharmacokinetics

Explaining Variability in Tacrolimus Pharmacokinetics to Optimize Early Exposure in Adult Kidney Transplant Recipients

(2009) Rogier R Press et al.   THERAPEUTIC DRUG MONITORING

Rimonabant Affects Cyclosporine A, but Not Tacrolimus Pharmacokinetics in Renal Transplant Recipients

(2009) Rune Amundsen et al.   TRANSPLANTATION

A Randomized Trial Comparing Renal Function in Older Kidney Transplant Patients Following Delayed Versus Immediate Tacrolimus Administration

(2009) Amado Andrés et al.   TRANSPLANTATION

Delayed Introduction of Reduced-Dose Tacrolimus, and Renal Function in Liver Transplantation: The ‘ReSpECT' Study

(2008) J. M. Neuberger et al.   AMERICAN JOURNAL OF TRANSPLANTATION

CYP3A5 genotype is not associated with a higher risk of acute rejection in tacrolimus-treated renal transplant recipients

(2008) Dennis A. Hesselink et al.   Pharmacogenetics and Genomics