Anti-LFA-1 or rapamycin overcome costimulation blockade-resistant rejection in sensitized bone marrow recipients

Expansion of Effector Memory TCR V 4+CD8+ T Cells Is Associated with Latent Infection-Mediated Resistance to Transplantation Tolerance

(2014) D. Stapler et al.   JOURNAL OF IMMUNOLOGY

Regulatory T Cells Exhibit Decreased Proliferation but Enhanced Suppression After Pulsing With Sirolimus

(2012) K. Singh et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Combined Costimulatory and Leukocyte Functional Antigen-1 Blockade Prevents Transplant Rejection Mediated by Heterologous Immune Memory Alloresponses

(2012) William H. Kitchens et al.   TRANSPLANTATION

LFA-1 Antagonism Inhibits Early Infiltration of Endogenous Memory CD8 T Cells into Cardiac Allografts and Donor-Reactive T Cell Priming

(2011) K. Setoguchi et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Integrin Antagonists Prevent Costimulatory Blockade-Resistant Transplant Rejection by CD8+ Memory T Cells

(2011) W. H. Kitchens et al.   AMERICAN JOURNAL OF TRANSPLANTATION

LFA-1 blockade induces effector and regulatory T-cell enrichment in lymph nodes and synergizes with CTLA-4Ig to inhibit effector function

(2011) N. M. Reisman et al.   BLOOD

Recent Progress and New Perspectives in Studying T Cell Responses to Allografts

(2010) A. Valujskikh et al.   AMERICAN JOURNAL OF TRANSPLANTATION

An MHC-Defined Primate Model Reveals Significant Rejection of Bone Marrow After Mixed Chimerism Induction Despite Full MHC Matching

(2010) C. P. Larsen et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Treg-Therapy Allows Mixed Chimerism and Transplantation Tolerance Without Cytoreductive Conditioning

(2010) N. Pilat et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Experience with a Novel Efalizumab-Based Immunosuppressive Regimen to Facilitate Single Donor Islet Cell Transplantation

(2010) N. A. Turgeon et al.   AMERICAN JOURNAL OF TRANSPLANTATION

LFA-1–specific therapy prolongs allograft survival in rhesus macaques

(2010) Idelberto R. Badell et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: Rapamycin Augments Pathogen-Specific but Not Graft-Reactive CD8+ T Cell Responses

(2010) I. R. Ferrer et al.   JOURNAL OF IMMUNOLOGY

Transplantation tolerance through mixed chimerism

(2010) Nina Pilat et al.   Nature Reviews Nephrology

The role of natural killer T cells in costimulation blockade-based mixed chimerism

(2010) Patrick-Nikolaus Nierlich et al.   TRANSPLANT INTERNATIONAL

B-Cell Immunity in the Context of T-Cell Tolerance after Combined Kidney and Bone Marrow Transplantation in Humans

(2009) F. Porcheray et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Memory T-cell-specific therapeutics in organ transplantation

(2009) Andrew J Page et al.   Current Opinion in Organ Transplantation

Translating costimulation blockade to the clinic: lessons learned from three pathways

(2009) Mandy L. Ford et al.   IMMUNOLOGICAL REVIEWS

Anti-TNF immunotherapy reduces CD8+ T cell–mediated antimicrobial activity against Mycobacterium tuberculosis in humans

(2009) Heiko Bruns et al.   JOURNAL OF CLINICAL INVESTIGATION

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates

(2009) Tim A Weaver et al.   NATURE MEDICINE

Hematopoietic Cell Transplantation for Tolerance Induction: Animal Models to Clinical Trials

(2009) Megan Sykes   TRANSPLANTATION

Bortezomib Can Suppress Activation of Rapamycin-Resistant Memory T Cells Without Affecting Regulatory T-Cell Viability in Non-Human Primates

(2009) Jung-Sik Kim et al.   TRANSPLANTATION

HLA-Mismatched Renal Transplantation without Maintenance Immunosuppression

(2008) Tatsuo Kawai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Tolerance and Chimerism after Renal and Hematopoietic-Cell Transplantation

(2008) John D. Scandling et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of TNF-α reduces transplant arteriosclerosis in a murine aortic transplant model

(2008) Martina Wollin et al.   TRANSPLANT INTERNATIONAL