Regulatory T Cells Exhibit Decreased Proliferation but Enhanced Suppression After Pulsing With Sirolimus

Cutting Edge: Foxp3-Mediated Induction of Pim 2 Allows Human T Regulatory Cells to Preferentially Expand in Rapamycin

(2014) Samik Basu et al.   JOURNAL OF IMMUNOLOGY

CD28 Costimulation Is Essential for Human T Regulatory Expansion and Function

(2014) T. N. Golovina et al.   JOURNAL OF IMMUNOLOGY

Generation and Large-Scale Expansion of Human Inducible Regulatory T Cells That Suppress Graft-Versus-Host Disease

(2011) K. L. Hippen et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Tregs prevent GVHD and promote immune reconstitution in HLA-haploidentical transplantation

(2011) M. Di Ianni et al.   BLOOD

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

CTLA-4-Ig Therapy Diminishes the Frequency but Enhances the Function of Treg Cells in Patients with Rheumatoid Arthritis

(2011) Crisol Álvarez-Quiroga et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice

(2011) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Retinoic Acid and Rapamycin Differentially Affect and Synergistically Promote the Ex Vivo Expansion of Natural Human T Regulatory Cells

(2011) Tatiana N. Golovina et al.   PLoS One

Massive ex Vivo Expansion of Human Natural Regulatory T Cells (Tregs) with Minimal Loss of in Vivo Functional Activity

(2011) K. L. Hippen et al.   Science Translational Medicine

Clinical perspectives for regulatory T cells in transplantation tolerance

(2011) Keli L. Hippen et al.   SEMINARS IN IMMUNOLOGY

Selective Targeting of Human Alloresponsive CD8+ Effector Memory T Cells Based on CD2 Expression

(2010) D. J. Lo et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Infusion of ex vivo expanded T regulatory cells in adults transplanted with umbilical cord blood: safety profile and detection kinetics

(2010) C. G. Brunstein et al.   BLOOD

CD4+ regulatory T cells in solid organ transplantation

(2010) Fadi Issa et al.   Current Opinion in Organ Transplantation

An Oscillatory Switch in mTOR Kinase Activity Sets Regulatory T Cell Responsiveness

(2010) Claudio Procaccini et al.   IMMUNITY

The immune responses of central and effector memory BCG-specific CD4+ T cells in BCG-vaccinated PPD+ donors were modulated by Treg cells

(2010) Li Li et al.   IMMUNOBIOLOGY

Immunoregulatory Pathways Controlling Progression of Autoimmunity in NOD Mice

(2009) Sylvaine You et al.   Annals of the New York Academy of Sciences

Plasticity of CD4+ FoxP3+ T cells

(2009) Xuyu Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Human T Regulatory Cell Therapy: Take a Billion or So and Call Me in the Morning

(2009) James L. Riley et al.   IMMUNITY

Mammalian Target of Rapamycin Inhibition and Alloantigen-Specific Regulatory T Cells Synergize To Promote Long-Term Graft Survival in Immunocompetent Recipients

(2009) G. Raimondi et al.   JOURNAL OF IMMUNOLOGY

Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates

(2009) Tim A Weaver et al.   NATURE MEDICINE

Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs

(2009) K. Bocian et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Heterogeneity of natural Foxp3+T cells: A committed regulatory T-cell lineage and an uncommitted minor population retaining plasticity

(2009) Noriko Komatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Characterization of Naturally Occurring CD4+CD25+ Regulatory T Cells in Rhesus Monkeys

(2009) Krista G. Haanstra et al.   TRANSPLANTATION

Expanded Nonhuman Primate Tregs Exhibit a Unique Gene Expression Signature and Potently Downregulate Alloimmune Responses

(2008) A. Anderson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Effect of Costimulatory and Interleukin 2 Receptor Blockade on Regulatory T Cells in Renal Transplantation

(2008) J. A. Bluestone et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Umbilical cord blood regulatory T-cell expansion and functional effects of tumor necrosis factor receptor family members OX40 and 4-1BB expressed on artificial antigen-presenting cells

(2008) K. L. Hippen et al.   BLOOD

CD4+CD25+ Treg cells inhibit human memory    T cells to produce IFN-  in response to M tuberculosis antigen ESAT-6

(2008) L. Li et al.   BLOOD

Expansion of Human Regulatory T-Cells From Patients With Type 1 Diabetes

(2008) A. L. Putnam et al.   DIABETES

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE