The microcirculation: linking trauma and coagulopathy

Admission Rapid Thrombelastography Can Replace Conventional Coagulation Tests in the Emergency Department

(2012) John B. Holcomb et al.   ANNALS OF SURGERY

Elderly trauma patients have high circulating noradrenaline levels but attenuated release of adrenaline, platelets, and leukocytes in response to increasing injury severity

(2012) Pär I. Johansson et al.   CRITICAL CARE MEDICINE

Acute traumatic coagulopathy

(2012) Daniel Frith et al.   Current Opinion in Anesthesiology

Lightweight noninvasive trauma monitor for early indication of central hypovolemia and tissue acidosis

(2012) Babs R. Soller et al.   Journal of Trauma and Acute Care Surgery

High levels of soluble VEGF receptor 1 early after trauma are associated with shock, sympathoadrenal activation, glycocalyx degradation and inflammation in severely injured patients: a prospective study

(2012) Sisse R Ostrowski et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Monitoring the microcirculation

(2012) Daniel De Backer et al.   JOURNAL OF CLINICAL MONITORING AND COMPUTING

Peripheral tissue oxygenation improves during ED treatment of acute heart failure

(2011) Christopher J. Hogan et al.   AMERICAN JOURNAL OF EMERGENCY MEDICINE

Plasma Restoration of Endothelial Glycocalyx in a Rodent Model of Hemorrhagic Shock

(2011) Rosemary A. Kozar et al.   ANESTHESIA AND ANALGESIA

A High Admission Syndecan-1 Level, A Marker of Endothelial Glycocalyx Degradation, Is Associated With Inflammation, Protein C Depletion, Fibrinolysis, and Increased Mortality in Trauma Patients

(2011) Pär I. Johansson et al.   ANNALS OF SURGERY

Examining platelet–fibrin interactions during traumatic shock in a swine model using platelet contractile force and clot elastic modulus

(2011) Nathan J. White et al.   BLOOD COAGULATION & FIBRINOLYSIS

Emerging treatment strategies for trauma-induced coagulopathy

(2011) B. Sorensen et al.   BRITISH JOURNAL OF SURGERY

High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality

(2011) P. I. JOHANSSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Modulation of Syndecan-1 Shedding after Hemorrhagic Shock and Resuscitation

(2011) Ricky J. Haywood-Watson et al.   PLoS One

Effects of a combination hemoglobin based oxygen carrier–hypertonic saline solution on oxygen transport in the treatment of traumatic shock

(2011) Benjamin Leong et al.   RESUSCITATION

Animal models of trauma-induced coagulopathy

(2011) Daniel Frith et al.   THROMBOSIS RESEARCH

The Association of Blood Component Use Ratios With the Survival of Massively Transfused Trauma Patients With and Without Severe Brain Injury

(2011) Philip C. Spinella et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Variations Between Level I Trauma Centers in 24-Hour Mortality in Severely Injured Patients Requiring a Massive Transfusion

(2011) Charles E. Wade et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Hemostatic and Pharmacologic Resuscitation: Results of a Long-Term Survival Study in a Swine PolyTrauma Model

(2011) Hasan B. Alam et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Crystalloid Resuscitation Improves Survival in Trauma Patients Receiving Low Ratios of Fresh Frozen Plasma to Packed Red Blood Cells

(2011) Nicholas Spoerke et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

High Ratios of Plasma and Platelets to Packed Red Blood Cells Do Not Affect Mortality in Nonmassively Transfused Patients

(2011) Chitra N. Sambasivan et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

A High Fresh Frozen Plasma: Packed Red Blood Cell Transfusion Ratio Decreases Mortality in All Massively Transfused Trauma Patients Regardless of Admission International Normalized Ratio

(2011) Lisa M. Brown et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Effect of High Product Ratio Massive Transfusion on Mortality in Blunt and Penetrating Trauma Patients

(2011) Susan E. Rowell et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

High circulating adrenaline levels at admission predict increased mortality after trauma

(2011) Pär Ingemar Johansson et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Gerinnungsmanagement bei traumatisch bedingter Massivblutung – Empfehlungen der Arbeitsgruppe für perioperative Gerinnung der ÖGARI

(2010) Dietmar Fries et al.   ANASTHESIOLOGIE INTENSIVMEDIZIN NOTFALLMEDIZIN SCHMERZTHERAPIE

Role of fibrinogen in trauma-induced coagulopathy

(2010) D Fries et al.   BRITISH JOURNAL OF ANAESTHESIA

Early coagulopathy in trauma patients: An on-scene and hospital admission study

(2010) Bernard Floccard et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

Monitoring the microcirculation in the critically ill patient: current methods and future approaches

(2010) Daniel De Backer et al.   INTENSIVE CARE MEDICINE

Oxygen transport characterization of a human model of progressive hemorrhage

(2010) Kevin R. Ward et al.   RESUSCITATION

ASSESSING SHOCK RESUSCITATION STRATEGIES BY OXYGEN DEBT REPAYMENT

(2010) Robert Wayne Barbee et al.   SHOCK

Initial resuscitation with plasma and other blood components reduced bleeding compared to hetastarch in anesthetized swine with uncontrolled splenic hemorrhage

(2010) Jill L. Sondeen et al.   TRANSFUSION

Systemic central venous oxygen saturation is associated with clot strength during traumatic hemorrhagic shock: A preclinical observational model

(2010) Nathan J White et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

Protective Effects of Fresh Frozen Plasma on Vascular Endothelial Permeability, Coagulation, and Resuscitation After Hemorrhagic Shock Are Time Dependent and Diminish Between Days 0 and 5 After Thaw

(2010) Shibani Pati et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Lyophilized Plasma for Resuscitation in a Swine Model of Severe Injury

(2009) Nicholas Spoerke   ARCHIVES OF SURGERY

Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion

(2009) D. Chappell et al.   CARDIOVASCULAR RESEARCH

Coagulopathy and traumatic shock: Characterizing hemostatic function during the critical period prior to fluid resuscitation

(2009) Nathan J. White et al.   RESUSCITATION

Acute Coagulopathy of Trauma: Hypoperfusion Induces Systemic Anticoagulation and Hyperfibrinolysis

(2009) Karim Brohi et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Testing of Blood Products in a Polytrauma Model: Results of a Multi-Institutional Randomized Preclinical Trial

(2009) Hasan B. Alam et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Resuscitating the Microcirculation in Sepsis: The Central Role of Nitric Oxide, Emerging Concepts for Novel Therapies, and Challenges for Clinical Trials

(2008) Stephen Trzeciak et al.   ACADEMIC EMERGENCY MEDICINE

REPRODUCIBILITY OF AN ANIMAL MODEL SIMULATING COMPLEX COMBAT-RELATED INJURY IN A MULTIPLE-INSTITUTION FORMAT

(2008) S. David Cho et al.   SHOCK

Development and Testing of Freeze-Dried Plasma for the Treatment of Trauma-Associated Coagulopathy

(2008) Fahad Shuja et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Massive Transfusion in Trauma Patients: Tissue Hemoglobin Oxygen Saturation Predicts Poor Outcome

(2008) Frederick A. Moore et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE