Manipulating Adenovirus Hexon Hypervariable Loops Dictates Immune Neutralisation and Coagulation Factor X-dependent Cell Interaction In Vitro and In Vivo

Natural antibodies as a sensor of electronegative damage-associated molecular patterns (DAMPs)

(2014) Koji Uchida   FREE RADICAL BIOLOGY AND MEDICINE

Multispecificity of Immunoglobulin M Antibodies Raised against Advanced Glycation End Products

(2013) Miho Chikazawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of novel small molecule inhibitors of adenovirus gene transfer using a high throughput screening approach

(2013) Margaret R. Duffy et al.   JOURNAL OF CONTROLLED RELEASE

Coagulation Factor Binding Orientation and Dimerization May Influence Infectivity of Adenovirus-Coagulation Factor Complexes

(2013) E. E. Irons et al.   JOURNAL OF VIROLOGY

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement

(2013) Zhili Xu et al.   NATURE MEDICINE

Molecular evolution of human adenoviruses

(2013) Christopher M. Robinson et al.   Scientific Reports

Adenovirus Serotype 26 Utilizes CD46 as a Primary Cellular Receptor and Only Transiently Activates T Lymphocytes following Vaccination of Rhesus Monkeys

(2012) H. Li et al.   JOURNAL OF VIROLOGY

Coagulation Factor X Activates Innate Immunity to Human Species C Adenovirus

(2012) K. Doronin et al.   SCIENCE

IgM and its receptors: Structural and functional aspects

(2011) V. B. Klimovich   BIOCHEMISTRY-MOSCOW

Coagulation factor X mediates adenovirus type 5 liver gene transfer in non-human primates (Microcebus murinus)

(2011) R Alba et al.   GENE THERAPY

Identification of Adenovirus Serotype 5 Hexon Regions That Interact with Scavenger Receptors

(2011) R. Khare et al.   JOURNAL OF VIROLOGY

A Cluster of Basic Amino Acids in the Factor X Serine Protease Mediates Surface Attachment of Adenovirus/FX Complexes

(2011) M. R. Duffy et al.   JOURNAL OF VIROLOGY

Adenovirus-Based Vaccines: Comparison of Vectors from Three Species ofAdenoviridae

(2010) H. Chen et al.   JOURNAL OF VIROLOGY

New insights into the molecular mechanisms of classical complement activation

(2010) Mihaela Kojouharova et al.   MOLECULAR IMMUNOLOGY

Requirements for Receptor Engagement during Infection by Adenovirus Complexed with Blood Coagulation Factor X

(2010) Angela C. Bradshaw et al.   PLoS Pathogens

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

(2009) R. Alba et al.   BLOOD

Virus Binding to a Plasma Membrane Receptor Triggers Interleukin-1α-Mediated Proinflammatory Macrophage Response In Vivo

(2009) Nelson C. Di Paolo et al.   IMMUNITY

Adenovirus Activates Complement by Distinctly Different Mechanisms In Vitro and In Vivo: Indirect Complement Activation by Virions In Vivo

(2009) J. Tian et al.   JOURNAL OF VIROLOGY

Influence of Coagulation Factor X on In Vitro and In Vivo Gene Delivery by Adenovirus (Ad) 5, Ad35, and Chimeric Ad5/Ad35 Vectors

(2009) Jenny A Greig et al.   MOLECULAR THERAPY

The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

(2009) Elena Seiradake et al.   PLoS Pathogens

Adenovirus Serotype 5 Hexon Mediates Liver Gene Transfer

(2008) Simon N. Waddington et al.   CELL

Adenoviruses in Immunocompromised Hosts

(2008) M. Echavarria   CLINICAL MICROBIOLOGY REVIEWS

Effect of Neutralizing Sera on Factor X-Mediated Adenovirus Serotype 5 Gene Transfer

(2008) A. L. Parker et al.   JOURNAL OF VIROLOGY

Substitution of Hexon Hypervariable Region 5 of Adenovirus Serotype 5 Abrogates Blood Factor Binding and Limits Gene Transfer to Liver

(2008) Frédéric Vigant et al.   MOLECULAR THERAPY

Adenovirus serotype 5 hexon is critical for virus infection of hepatocytes in vivo

(2008) O. Kalyuzhniy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA