Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques

Live Simian Immunodeficiency Virus Vaccine Correlate of Protection: Local Antibody Production and Concentration on the Path of Virus Entry

(2014) Qingsheng Li et al.   JOURNAL OF IMMUNOLOGY

Specificity and 6-Month Durability of Immune Responses Induced by DNA and Recombinant Modified Vaccinia Ankara Vaccines Expressing HIV-1 Virus-Like Particles

(2014) Paul A. Goepfert et al.   JOURNAL OF INFECTIOUS DISEASES

Capacity for Infectious HIV-1 Virion Capture Differs by Envelope Antibody Specificity

(2014) P. Liu et al.   JOURNAL OF VIROLOGY

Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection

(2014) P. Acharya et al.   JOURNAL OF VIROLOGY

HIV-1 Vaccine-Induced C1 and V2 Env-Specific Antibodies Synergize for Increased Antiviral Activities

(2014) Justin Pollara et al.   JOURNAL OF VIROLOGY

The HIV-1 gp120 CD4-Bound Conformation Is Preferentially Targeted by Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies in Sera from HIV-1-Infected Individuals

(2014) Maxime Veillette et al.   JOURNAL OF VIROLOGY

Enhanced neonatal Fc receptor function improves protection against primate SHIV infection

(2014) Sung-Youl Ko et al.   NATURE

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

(2014) Marie Pancera et al.   NATURE

Vaccine-Induced Env V1-V2 IgG3 Correlates with Lower HIV-1 Infection Risk and Declines Soon After Vaccination

(2014) N. L. Yates et al.   Science Translational Medicine

Structural characterization of a fusion glycoprotein from a retrovirus that undergoes a hybrid 2-step entry mechanism

(2013) Halil Aydin et al.   FASEB JOURNAL

Vaccine Induction of Antibodies against a Structurally Heterogeneous Site of Immune Pressure within HIV-1 Envelope Protein Variable Regions 1 and 2

(2013) Hua-Xin Liao et al.   IMMUNITY

HIV-1 neutralizing antibodies: understanding nature's pathways

(2013) John R. Mascola et al.   IMMUNOLOGICAL REVIEWS

Neutralizing IgG at the Portal of Infection Mediates Protection against Vaginal Simian/Human Immunodeficiency Virus Challenge

(2013) K. Klein et al.   JOURNAL OF VIROLOGY

Infectious Virion Capture by HIV-1 gp120-Specific IgG from RV144 Vaccinees

(2013) P. Liu et al.   JOURNAL OF VIROLOGY

Interaction with Cellular CD4 Exposes HIV-1 Envelope Epitopes Targeted by Antibody-Dependent Cell-Mediated Cytotoxicity

(2013) M. Veillette et al.   JOURNAL OF VIROLOGY

HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life

(2013) N L Yates et al.   Mucosal Immunology

Protective effect of vaginal application of neutralizing and nonneutralizing inhibitory antibodies against vaginal SHIV challenge in macaques

(2013) C Moog et al.   Mucosal Immunology

Efficacy Trial of a DNA/rAd5 HIV-1 Preventive Vaccine

(2013) Scott M. Hammer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plasma IgG to Linear Epitopes in the V2 and V3 Regions of HIV-1 gp120 Correlate with a Reduced Risk of Infection in the RV144 Vaccine Efficacy Trial

(2013) Raphael Gottardo et al.   PLoS One

Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG

(2013) G. D. Tomaras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Antibodies that Neutralize HIV-1: Identification, Structures, and B Cell Ontogenies

(2012) Peter D. Kwong et al.   IMMUNITY

Magnitude and Breadth of the Neutralizing Antibody Response in the RV144 and Vax003 HIV-1 Vaccine Efficacy Trials

(2012) D. C. Montefiori et al.   JOURNAL OF INFECTIOUS DISEASES

Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies from an HIV-1 Vaccine Efficacy Trial Target Multiple Epitopes and Preferentially Use the VH1 Gene Family

(2012) M. Bonsignori et al.   JOURNAL OF VIROLOGY

A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced Fc RIIIa-Mediated Antiviral Activity In Vitro but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques

(2012) B. Moldt et al.   JOURNAL OF VIROLOGY

Immune-Correlates Analysis of an HIV-1 Vaccine Efficacy Trial

(2012) Barton F. Haynes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

(2012) Y. Guan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly potent HIV-specific antibody neutralization in vitro translates into effective protection against mucosal SHIV challenge in vivo

(2012) B. Moldt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunization with HIV-1 gp41 Subunit Virosomes Induces Mucosal Antibodies Protecting Nonhuman Primates against Vaginal SHIV Challenges

(2011) Morgane Bomsel et al.   IMMUNITY

Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated

(2011) Hua-Xin Liao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An HIV-1 gp120 Envelope Human Monoclonal Antibody That Recognizes a C1 Conformational Epitope Mediates Potent Antibody-Dependent Cellular Cytotoxicity (ADCC) Activity and Defines a Common ADCC Epitope in Human HIV-1 Serum

(2011) G. Ferrari et al.   JOURNAL OF VIROLOGY

Dynamic Antibody Specificities and Virion Concentrations in Circulating Immune Complexes in Acute to Chronic HIV-1 Infection

(2011) P. Liu et al.   JOURNAL OF VIROLOGY

Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

(2011) G. D. Tomaras et al.   JOURNAL OF VIROLOGY

Broadly neutralizing human antibody that recognizes the receptor-binding pocket of influenza virus hemagglutinin

(2011) J. R. R. Whittle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody

(2011) D. R. Burton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection

(2011) Suzanne Willey et al.   Retrovirology

Neutralizing Antibodies and Control of HIV: Moves and Countermoves

(2011) Ann J. Hessell et al.   Current HIV/AIDS Reports

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Estimating time since infection in early homogeneous HIV-1 samples using a poisson model

(2010) Elena E Giorgi et al.   BMC BIOINFORMATICS

Induction of Immunity to Human Immunodeficiency Virus Type-1 by Vaccination

(2010) M. Juliana McElrath et al.   IMMUNITY

Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce β-chemokines

(2010) M. Anthony Moody et al.   JOURNAL OF EXPERIMENTAL MEDICINE

GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium

(2010) R. Shen et al.   JOURNAL OF IMMUNOLOGY

A Substantial Transmission Bottleneck among Newly and Recently HIV‐1–Infected Injection Drug Users in St Petersburg, Russia

(2010) Alexey E. Masharsky et al.   JOURNAL OF INFECTIOUS DISEASES

A New Clustering of Antibody CDR Loop Conformations

(2010) Benjamin North et al.   JOURNAL OF MOLECULAR BIOLOGY

Studies of the "Chain Reversal Regions" of the Avian Sarcoma/Leukosis Virus (ASLV) and Ebolavirus Fusion Proteins: Analogous Residues Are Important, and a His Residue Unique to EnvA Affects the pH Dependence of ASLV Entry

(2010) S. E. Delos et al.   JOURNAL OF VIROLOGY

In-Solution Virus Capture Assay Helps Deconstruct Heterogeneous Antibody Recognition of Human Immunodeficiency Virus Type 1

(2010) D. P. Leaman et al.   JOURNAL OF VIROLOGY

Wide Variation in the Multiplicity of HIV-1 Infection among Injection Drug Users

(2010) K. J. Bar et al.   JOURNAL OF VIROLOGY

Topological Layers in the HIV-1 gp120 Inner Domain Regulate gp41 Interaction and CD4-Triggered Conformational Transitions

(2010) Andrés Finzi et al.   MOLECULAR CELL

Prolonged exposure of the HIV-1 gp41 membrane proximal region with L669S substitution

(2010) X. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Replication competent molecular clones of HIV-1 expressing Renilla luciferase facilitate the analysis of antibody inhibition in PBMC

(2010) Tara G. Edmonds et al.   VIROLOGY

Strategies for eliciting HIV-1 inhibitory antibodies

(2010) Georgia D Tomaras et al.   Current Opinion in HIV and AIDS

Is developing an HIV-1 vaccine possible?

(2010) Barton F Haynes et al.   Current Opinion in HIV and AIDS

High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men

(2010) Hui Li et al.   PLoS Pathogens

Herpes simplex virus 2 serostatus and viral loads of HIV-1 in blood and semen as risk factors for HIV transmission among men who have sex with men

(2009) David M Butler et al.   AIDS

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

(2009) Brandon F. Keele et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Modeling sequence evolution in acute HIV-1 infection

(2009) Ha Youn Lee et al.   JOURNAL OF THEORETICAL BIOLOGY

High-throughput isolation of immunoglobulin genes from single human B cells and expression as monoclonal antibodies

(2009) Hua-Xin Liao et al.   JOURNAL OF VIROLOGICAL METHODS

Broadly Neutralizing Monoclonal Antibodies 2F5 and 4E10 Directed against the Human Immunodeficiency Virus Type 1 gp41 Membrane-Proximal External Region Protect against Mucosal Challenge by Simian-Human Immunodeficiency Virus SHIVBa-L

(2009) A. J. Hessell et al.   JOURNAL OF VIROLOGY

Quantitating the Multiplicity of Infection with Human Immunodeficiency Virus Type 1 Subtype C Reveals a Non-Poisson Distribution of Transmitted Variants

(2009) M.-R. Abrahams et al.   JOURNAL OF VIROLOGY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Functional, Non-Clonal IgMa-Restricted B Cell Receptor Interactions with the HIV-1 Envelope gp41 Membrane Proximal External Region

(2009) Laurent Verkoczy et al.   PLoS One

Inflammatory Genital Infections Mitigate a Severe Genetic Bottleneck in Heterosexual Transmission of Subtype A and C HIV-1

(2009) Richard E. Haaland et al.   PLoS Pathogens

Initial B-Cell Responses to Transmitted Human Immunodeficiency Virus Type 1: Virion-Binding Immunoglobulin M (IgM) and IgG Antibodies Followed by Plasma Anti-gp41 Antibodies with Ineffective Control of Initial Viremia

(2008) G. D. Tomaras et al.   JOURNAL OF VIROLOGY

Optimization of antibody binding to Fc RIIa enhances macrophage phagocytosis of tumor cells

(2008) J. O. Richards et al.   MOLECULAR CANCER THERAPEUTICS

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improving Defences at the Portal of HIV Entry: Mucosal and Innate Immunity

(2008) Robin J Shattock et al.   PLOS MEDICINE

N-terminal substitutions in HIV-1 gp41 reduce the expression of non-trimeric envelope glycoproteins on the virus

(2007) Antu K. Dey et al.   VIROLOGY