Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection

Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice

(2014) Brian D Henry et al.   NATURE BIOTECHNOLOGY

The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity

(2014) Lucy K. Shewell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Incomplete pneumolysin oligomers form membrane pores

(2014) A. F.- P. Sonnen et al.   Open Biology

Streptococcus pneumoniae Translocates into the Myocardium and Forms Unique Microlesions That Disrupt Cardiac Function

(2014) Armand O. Brown et al.   PLoS Pathogens

Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy

(2013) Bingfang Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

High incidence of septic shock caused by Streptococcus pneumoniae serotype 3 - a retrospective epidemiological study

(2013) Jonas Ahl et al.   BMC INFECTIOUS DISEASES

Prognostic value of troponins in sepsis: a meta-analysis

(2013) Francis Bessière et al.   INTENSIVE CARE MEDICINE

PKCα-Specific Phosphorylation of the Troponin Complex in Human Myocardium: A Functional and Proteomics Analysis

(2013) Viola Kooij et al.   PLoS One

Circulating Histones Are Mediators of Trauma-associated Lung Injury

(2012) Simon T. Abrams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Coping with Endoplasmic Reticulum Stress in the Cardiovascular System

(2012) Jody Groenendyk et al.   Annual Review of Physiology

The chemical chaperone 4-phenylbutyric acid attenuates pressure-overload cardiac hypertrophy by alleviating endoplasmic reticulum stress

(2012) Chang Sik Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cardiac Complications in Patients With Community-Acquired Pneumonia

(2012) Vicente F. Corrales-Medina et al.   CIRCULATION

Risk stratification and prognosis of acute cardiac events in hospitalized adults with community-acquired pneumonia

(2012) Diego Viasus et al.   JOURNAL OF INFECTION

T Regulatory Cells Control Susceptibility to Invasive Pneumococcal Pneumonia in Mice

(2012) Daniel R. Neill et al.   PLoS Pathogens

Activation of Akt Rescues Endoplasmic Reticulum Stress-Impaired Murine Cardiac Contractile Function via Glycogen Synthase Kinase-3β-Mediated Suppression of Mitochondrial Permeation Pore Opening

(2011) Yingmei Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

How to Interpret Elevated Cardiac Troponin Levels

(2011) Vinay S. Mahajan et al.   CIRCULATION

PKC-ing Is Believing

(2011) Stephen L. Belmonte et al.   CIRCULATION RESEARCH

Is community-acquired pneumonia an independent risk factor for cardiovascular disease?

(2011) A. Singanayagam et al.   EUROPEAN RESPIRATORY JOURNAL

Attenuation of endoplasmic reticulum stress using the chemical chaperone 4-phenylbutyric acid prevents cardiac fibrosis induced by isoproterenol

(2011) Pedro Ayala et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

The role of the membrane potential in chondrocyte volume regulation

(2011) Rebecca Lewis et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Vascular complications are associated with poor outcome in community-acquired pneumonia

(2011) P. Mandal et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Cardiac Complications in Patients with Community-Acquired Pneumonia: A Systematic Review and Meta-Analysis of Observational Studies

(2011) Vicente F. Corrales-Medina et al.   PLOS MEDICINE

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

(2010) Tetsuo Minamino et al.   CIRCULATION RESEARCH

Pneumolysin-induced CXCL8 production by nasopharyngeal epithelial cells is dependent on calcium flux and MAPK activation via Toll-like receptor 4

(2010) Semih Dogan et al.   MICROBES AND INFECTION

Pneumolysin Activates the NLRP3 Inflammasome and Promotes Proinflammatory Cytokines Independently of TLR4

(2010) Edel A. McNeela et al.   PLoS Pathogens

Protein kinase C in heart failure: a therapeutic target?

(2009) S. S. Palaniyandi et al.   CARDIOVASCULAR RESEARCH

Cardiac dysfunction in severe sepsis and septic shock

(2009) Sergio L Zanotti-Cavazzoni et al.   Current Opinion in Critical Care

Cardiac Troponin I Levels and Alveolar-arterial Oxygen Gradient in Patients with Community-acquired Pneumonia

(2009) Mahmoud Q. Moammar et al.   Heart Lung and Circulation

Characterization of Calumenin-SERCA2 Interaction in Mouse Cardiac Sarcoplasmic Reticulum

(2009) Sanjaya Kumar Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pneumolysin generates multiple conductance pores in the membrane of nucleated cells

(2008) Rana G. El-Rachkidy et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acute Myocardial Infarction in Hospitalized Patients with Community‐Acquired Pneumonia

(2008) Julio Ramirez et al.   CLINICAL INFECTIOUS DISEASES

Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation

(2008) Lei Ke et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cardiac troponins

(2008) Scott M. Wells et al.   JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY

Structural Basis of Protein Kinase C Isoform Function

(2008) Susan F. Steinberg   PHYSIOLOGICAL REVIEWS