Hepatitis C Virus RNA Replication Depends on Specific Cis- and Trans-Acting Activities of Viral Nonstructural Proteins
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Hepatitis C Virus RNA Replication Depends on Specific Cis- and Trans-Acting Activities of Viral Nonstructural Proteins
Authors
Keywords
Viral replication, Helicases, Hepatitis C virus, Transfection, RNA structure, RNA viruses, RNA-binding proteins, Serine proteases
Journal
PLoS Pathogens
Volume 11, Issue 4, Pages e1004817
Publisher
Public Library of Science (PLoS)
Online
2015-04-14
DOI
10.1371/journal.ppat.1004817
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Daclatasvir-Like Inhibitors of NS5A Block Early Biogenesis of Hepatitis C Virus–Induced Membranous Replication Factories, Independent of RNA Replication
- (2014) Carola Berger et al. GASTROENTEROLOGY
- The Bean Pod Mottle Virus RNA2-Encoded 58-Kilodalton Protein P58 Is Required in cis for RNA2 Accumulation
- (2014) J. Lin et al. JOURNAL OF VIROLOGY
- Dependence of Coronavirus RNA Replication on an NH2-Terminal Partial Nonstructural Protein 1 in cis
- (2014) Y.-P. Su et al. JOURNAL OF VIROLOGY
- The Linker Region of NS3 Plays a Critical Role in the Replication and Infectivity of Hepatitis C Virus
- (2014) A. Kohlway et al. JOURNAL OF VIROLOGY
- Daclatasvir plus Sofosbuvir for Previously Treated or Untreated Chronic HCV Infection
- (2014) Mark S. Sulkowski et al. NEW ENGLAND JOURNAL OF MEDICINE
- Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease
- (2013) Kenichi Morikawa et al. HEPATOLOGY
- Genetic Complementation of Hepatitis C Virus Nonstructural Protein Functions Associated with Replication Exhibits Requirements That Differ from Those for Virion Assembly
- (2013) M. R. Herod et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus RNA Replication and Virus Particle Assembly Require Specific Dimerization of the NS4A Protein Transmembrane Domain
- (2013) A. Kohlway et al. JOURNAL OF VIROLOGY
- The ins and outs of hepatitis C virus entry and assembly
- (2013) Brett D. Lindenbach et al. NATURE REVIEWS MICROBIOLOGY
- The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection
- (2013) Ralf Bartenschlager et al. NATURE REVIEWS MICROBIOLOGY
- Structure of Hepatitis C Virus Polymerase in Complex with Primer-Template RNA
- (2012) R. T. Mosley et al. JOURNAL OF VIROLOGY
- A Conserved Tandem Cyclophilin-Binding Site in Hepatitis C Virus Nonstructural Protein 5A Regulates Alisporivir Susceptibility
- (2012) H. Grise et al. JOURNAL OF VIROLOGY
- Intragenic Complementation of Hepatitis C Virus NS5A RNA Replication-Defective Alleles
- (2012) R. A. Fridell et al. JOURNAL OF VIROLOGY
- NIH Image to ImageJ: 25 years of image analysis
- (2012) Caroline A Schneider et al. NATURE METHODS
- DDB1 is a cellular substrate of NS3/4A protease and required for hepatitis C virus replication
- (2012) Xi Kang et al. VIROLOGY
- Recruitment and Activation of a Lipid Kinase by Hepatitis C Virus NS5A Is Essential for Integrity of the Membranous Replication Compartment
- (2011) Simon Reiss et al. Cell Host & Microbe
- Domain 3 of NS5A Protein from the Hepatitis C Virus Has Intrinsic α-Helical Propensity and Is a Substrate of Cyclophilin A
- (2011) Dries Verdegem et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- NS4B Self-Interaction through Conserved C-Terminal Elements Is Required for the Establishment of Functional Hepatitis C Virus Replication Complexes
- (2011) D. Paul et al. JOURNAL OF VIROLOGY
- Distinct Functions of NS5A in Hepatitis C Virus RNA Replication Uncovered by Studies with the NS5A Inhibitor BMS-790052
- (2011) R. A. Fridell et al. JOURNAL OF VIROLOGY
- Cyclophilin A Interacts with Domain II of Hepatitis C Virus NS5A and Stimulates RNA Binding in an Isomerase-Dependent Manner
- (2011) T. L. Foster et al. JOURNAL OF VIROLOGY
- Cotranslational Control of DNA Transposition: A Window of Opportunity
- (2011) Guy Duval-Valentin et al. MOLECULAR CELL
- A Cell-Based Assay for RNA Synthesis by the HCV Polymerase Reveals New Insights on Mechanism of Polymerase Inhibitors and Modulation by NS5A
- (2011) C. T. Ranjith-Kumar et al. PLoS One
- Properties of Hepatitis C virus minigenome containing mutated 5'UTR region and luciferase transgene
- (2010) J. Yang et al. ACTA VIROLOGICA
- Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV
- (2010) Todd C. Appleby et al. JOURNAL OF MOLECULAR BIOLOGY
- Hepatitis C Virus RNA Replication Requires a Conserved Structural Motif within the Transmembrane Domain of the NS5B RNA-Dependent RNA Polymerase
- (2010) V. Brass et al. JOURNAL OF VIROLOGY
- The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly
- (2010) T. Phan et al. JOURNAL OF VIROLOGY
- Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
- (2010) Min Gao et al. NATURE
- Cyclosporine Inhibits a Direct Interaction between Cyclophilins and Hepatitis C NS5A
- (2010) Fiona Fernandes et al. PLoS One
- Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
- (2010) M. Gu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Hepatitis C virus nonstructural protein 4B: a journey into unexplored territory
- (2010) Jérôme Gouttenoire et al. REVIEWS IN MEDICAL VIROLOGY
- Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays
- (2010) J. F. Spagnolo et al. RNA
- Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolylcis/transIsomerase Activity of Cyclophilins A and B
- (2009) Xavier Hanoulle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Expression of hepatitis C virus (HCV) structural proteins in trans facilitates encapsidation and transmission of HCV subgenomic RNA
- (2009) R. Adair et al. JOURNAL OF GENERAL VIROLOGY
- Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious Defective Particles
- (2009) L. Pacini et al. JOURNAL OF VIROLOGY
- Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes
- (2009) T. Phan et al. JOURNAL OF VIROLOGY
- Genetic Analysis of Hepatitis C Virus with Defective Genome and Its Infectivity in Vitro
- (2009) K. Sugiyama et al. JOURNAL OF VIROLOGY
- The NS4A Protein of Hepatitis C Virus Promotes RNA-Coupled ATP Hydrolysis by the NS3 Helicase
- (2009) R. K. F. Beran et al. JOURNAL OF VIROLOGY
- trans-Complementation of an NS2 Defect in a Late Step in Hepatitis C Virus (HCV) Particle Assembly and Maturation
- (2009) MinKyung Yi et al. PLoS Pathogens
- Translocation and Unwinding Mechanisms of RNA and DNA Helicases
- (2008) Anna Marie Pyle Annual Review of Biophysics
- Trans-encapsidation of hepatitis C virus subgenomic replicon RNA with viral structure proteins
- (2008) Koji Ishii et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Hepatitis C Viral NS3-4A Protease Activity Is Enhanced by the NS3 Helicase
- (2008) Rudolf K. F. Beran et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Hepatitis C Virus NS4B Protein Can trans-Complement Viral RNA Replication and Modulates Production of Infectious Virus
- (2008) D. M. Jones et al. JOURNAL OF VIROLOGY
- Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles
- (2008) E. Steinmann et al. JOURNAL OF VIROLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now