Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics

Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates

(2015) David C Watson et al.   GLYCOBIOLOGY

α-2,3-Sialyltransferase Expression Level Impacts the Kinetics of Lipooligosaccharide Sialylation, Complement Resistance, and the Ability of Neisseria gonorrhoeae to Colonize the Murine Genital Tract

(2015) Lisa A. Lewis et al.   mBio

Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future

(2014) M. Unemo et al.   CLINICAL MICROBIOLOGY REVIEWS

Parallel evolution of a self-signal: humans and new world monkeys independently lost the cell surface sugar Neu5Gc

(2014) Stevan A. Springer et al.   IMMUNOGENETICS

Human Factor H Interacts Selectively with Neisseria gonorrhoeae and Results in Species-Specific Complement Evasion

(2014) J. Ngampasutadol et al.   JOURNAL OF IMMUNOLOGY

Structural basis for sialic acid–mediated self-recognition by complement factor H

(2014) Bärbel S Blaum et al.   Nature Chemical Biology

Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

(2014) Preston S.K. Ng et al.   Nature Communications

A Simple Method for Assessment of Human Anti-Neu5Gc Antibodies Applied to Kawasaki Disease

(2013) Vered Padler-Karavani et al.   PLoS One

Immunization against a Saccharide Epitope Accelerates Clearance of Experimental Gonococcal Infection

(2013) Sunita Gulati et al.   PLoS Pathogens

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

The Relative Roles of Factor H Binding Protein, Neisserial Surface Protein A, and Lipooligosaccharide Sialylation in Regulation of the Alternative Pathway of Complement on Meningococci

(2012) L. A. Lewis et al.   JOURNAL OF IMMUNOLOGY

Properdin Is Critical for Antibody-Dependent Bactericidal Activity against Neisseria gonorrhoeae That Recruit C4b-Binding Protein

(2012) S. Gulati et al.   JOURNAL OF IMMUNOLOGY

Is Neisseria gonorrhoeae Initiating a Future Era of Untreatable Gonorrhea?: Detailed Characterization of the First Strain with High-Level Resistance to Ceftriaxone

(2011) Makoto Ohnishi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pasteurella multocida CMP-sialic acid synthetase and mutants of Neisseria meningitidis CMP-sialic acid synthetase with improved substrate promiscuity

(2011) Yanhong Li et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Chemoenzymatic synthesis of C8-modified sialic acids and related α2–3- and α2–6-linked sialosides

(2011) Hai Yu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement

(2011) T. Kajander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estradiol-Treated Female Mice as Surrogate Hosts for Neisseria gonorrhoeae Genital Tract Infections

(2011) Ann E. Jerse et al.   Frontiers in Microbiology

Enzymatic synthesis and properties of glycoconjugates with legionaminic acid as a replacement for neuraminic acid

(2010) D. C. Watson et al.   GLYCOBIOLOGY

Complement control protein factor H: The good, the bad, and the inadequate

(2010) Viviana P. Ferreira et al.   MOLECULAR IMMUNOLOGY

Advances in the Biology and Chemistry of Sialic Acids

(2009) Xi Chen et al.   ACS Chemical Biology

The CMP-legionaminic acid pathway in Campylobacter: Biosynthesis involving novel GDP-linked precursors

(2009) Ian C Schoenhofen et al.   GLYCOBIOLOGY

Sensitive and Specific Detection of the Non-Human Sialic Acid N-Glycolylneuraminic Acid In Human Tissues and Biotherapeutic Products

(2009) Sandra L. Diaz et al.   PLoS One

Innovations in host and microbial sialic acid biosynthesis revealed by phylogenomic prediction of nonulosonic acid structure

(2009) A. L. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphoethanolamine Substitution of Lipid A and Resistance of Neisseria gonorrhoeae to Cationic Antimicrobial Peptides and Complement-Mediated Killing by Normal Human Serum

(2008) L. A. Lewis et al.   INFECTION AND IMMUNITY