Evolutionary and Functional Analysis of Old World Primate TRIM5 Reveals the Ancient Emergence of Primate Lentiviruses and Convergent Evolution Targeting a Conserved Capsid Interface

Primate phylogenetic relationships and divergence dates inferred from complete mitochondrial genomes

(2014) Luca Pozzi et al.   MOLECULAR PHYLOGENETICS AND EVOLUTION

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6

(2014) Akash Bhattacharya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

(2014) David C. Goldstone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The tripartite motif coiled-coil is an elongated antiparallel hairpin dimer

(2014) J. G. Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

(2014) Amanda J. Price et al.   PLoS Pathogens

A Cyclophilin Homology Domain-Independent Role for Nup358 in HIV-1 Infection

(2014) Anne M. Meehan et al.   PLoS Pathogens

High efficiency gene transfer to airways of mice using influenza hemagglutinin pseudotyped lentiviral vectors

(2013) Manij Patel et al.   JOURNAL OF GENE MEDICINE

A Comparison of Murine Leukemia Viruses That Escape from Human and Rhesus Macaque TRIM5 s

(2013) S. Ohkura et al.   JOURNAL OF VIROLOGY

A Mitogenomic Phylogeny of Living Primates

(2013) Knut Finstermeier et al.   PLoS One

Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors

(2013) João I Mamede et al.   Retrovirology

Binding of the rhesus TRIM5α PRYSPRY domain to capsid is necessary but not sufficient for HIV-1 restriction

(2013) Yang Yang et al.   VIROLOGY

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

Gain-of-Sensitivity Mutations in a Trim5-Resistant Primary Isolate of Pathogenic SIV Identify Two Independent Conserved Determinants of Trim5α Specificity

(2013) Kevin R. McCarthy et al.   PLoS Pathogens

Convergence and Divergence in the Evolution of the APOBEC3G-Vif Interaction Reveal Ancient Origins of Simian Immunodeficiency Viruses

(2013) Alex A. Compton et al.   PLoS Pathogens

APOBEC3G Polymorphism as a Selective Barrier to Cross-Species Transmission and Emergence of Pathogenic SIV and AIDS in a Primate Host

(2013) Annabel Krupp et al.   PLoS Pathogens

Evolutionary Toggling of Vpx/Vpr Specificity Results in Divergent Recognition of the Restriction Factor SAMHD1

(2013) Oliver I. Fregoso et al.   PLoS Pathogens

Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein

(2012) Nadine Laguette et al.   Cell Host & Microbe

Endogenous Lentiviruses in the Ferret Genome

(2012) J. Cui et al.   JOURNAL OF VIROLOGY

Endogenous Lentiviral Elements in the Weasel Family (Mustelidae)

(2012) G.-Z. Han et al.   MOLECULAR BIOLOGY AND EVOLUTION

FastML: a web server for probabilistic reconstruction of ancestral sequences

(2012) H. Ashkenazy et al.   NUCLEIC ACIDS RESEARCH

Structure of the rhesus monkey TRIM5  PRYSPRY domain, the HIV capsid recognition module

(2012) N. Biris et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CPSF6 Defines a Conserved Capsid Interface that Modulates HIV-1 Replication

(2012) Amanda J. Price et al.   PLoS Pathogens

Ancient origin of a deletion in human BST2/Tetherin that confers protection against viral zoonoses

(2011) Daniel Sauter et al.   HUMAN MUTATION

Unique Spectrum of Activity of Prosimian TRIM5  against Exogenous and Endogenous Retroviruses

(2011) N. Rahm et al.   JOURNAL OF VIROLOGY

Viral evolution in deep time: lentiviruses and mammals

(2011) Robert J. Gifford   TRENDS IN GENETICS

Two-stepping through time: mammals and viruses

(2011) Nicholas R. Meyerson et al.   TRENDS IN MICROBIOLOGY

Paleovirology—ghosts and gifts of viruses past

(2011) Maulik R Patel et al.   Current Opinion in Virology

A Molecular Phylogeny of Living Primates

(2011) Polina Perelman et al.   PLoS Genetics

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein

(2011) Sadayuki Ohkura et al.   PLoS Pathogens

Generation of human TRIM5α mutants with high HIV-1 restriction activity

(2010) Q T Pham et al.   GENE THERAPY

Ancient Adaptive Evolution of Tetherin Shaped the Functions of Vpu and Nef in Human Immunodeficiency Virus and Primate Lentiviruses

(2010) E. S. Lim et al.   JOURNAL OF VIROLOGY

Island Biogeography Reveals the Deep History of SIV

(2010) M. Worobey et al.   SCIENCE

New Algorithms and Methods to Estimate Maximum-Likelihood Phylogenies: Assessing the Performance of PhyML 3.0

(2010) Stéphane Guindon et al.   SYSTEMATIC BIOLOGY

Paleovirology—Modern Consequences of Ancient Viruses

(2010) Michael Emerman et al.   PLOS BIOLOGY

TRIM5 Suppresses Cross-Species Transmission of a Primate Immunodeficiency Virus and Selects for Emergence of Resistant Variants in the New Species

(2010) Andrea Kirmaier et al.   PLOS BIOLOGY

Impact of Simian Immunodeficiency Virus Infection on Chimpanzee Population Dynamics

(2010) Rebecca S. Rudicell et al.   PLoS Pathogens

Impact of novel TRIM5α variants, Gly110Arg and G176del, on the anti-HIV-1 activity and the susceptibility to HIV-1 infection

(2009) Toshiaki Nakajima et al.   AIDS

AIDS in African Nonhuman Primate Hosts of SIVs: A New Paradigm of SIV Infection

(2009) Ivona Pandrea et al.   CURRENT HIV RESEARCH

Molecular evolution of the antiretroviral TRIM5 gene

(2009) Welkin E. Johnson et al.   IMMUNOGENETICS

NMR Structure of the N-Terminal Domain of Capsid Protein from the Mason–Pfizer Monkey Virus

(2009) Pavel Macek et al.   JOURNAL OF MOLECULAR BIOLOGY

An Invariant Surface Patch on the TRIM5  PRYSPRY Domain Is Required for Retroviral Restriction but Dispensable for Capsid Binding

(2009) S. Sebastian et al.   JOURNAL OF VIROLOGY

Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

(2009) Brandon F. Keele et al.   NATURE

Impact of a single amino acid in the variable region 2 of the Old World monkey TRIM5α SPRY (B30.2) domain on anti-human immunodeficiency virus type 2 activity

(2009) Ken Kono et al.   VIROLOGY

Parallel Germline Infiltration of a Lentivirus in Two Malagasy Lemurs

(2009) Clément Gilbert et al.   PLoS Genetics

Structure of the Capsid Amino-Terminal Domain from the Betaretrovirus, Jaagsiekte Sheep Retrovirus

(2008) Gulnahar B. Mortuza et al.   JOURNAL OF MOLECULAR BIOLOGY

Identification of Postentry Restrictions to Mason-Pfizer Monkey Virus Infection in New World Monkey Cells

(2008) W. E. Diehl et al.   JOURNAL OF VIROLOGY

Primate Lentivirus Capsid Sensitivity to TRIM5 Proteins

(2008) Z. Kratovac et al.   JOURNAL OF VIROLOGY

Rhesus Macaque TRIM5 Alleles Have Divergent Antiretroviral Specificities

(2008) S. J. Wilson et al.   JOURNAL OF VIROLOGY

Sharing of Endogenous Lentiviral Gene Fragments among Leporid Lineages Separated for More than 12 Million Years

(2008) W. van der Loo et al.   JOURNAL OF VIROLOGY

TRIMCyp expression in Old World primates Macaca nemestrina and Macaca fascicularis

(2008) G. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent genesis of chimeric TRIM5-cyclophilin proteins in two primate species

(2008) C. A. Virgen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Independent evolution of an antiviral TRIMCyp in rhesus macaques

(2008) S. J. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A transitional endogenous lentivirus from the genome of a basal primate and implications for lentivirus evolution

(2008) R. J. Gifford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts

(2008) Ivona Pandrea et al.   TRENDS IN IMMUNOLOGY

Identification of a RELIK orthologue in the European hare (Lepus europaeus) reveals a minimum age of 12 million years for the lagomorph lentiviruses

(2008) Z. Keckesova et al.   VIROLOGY

Evolution of a TRIM5-CypA Splice Isoform in Old World Monkeys

(2008) Ruchi M. Newman et al.   PLoS Pathogens

Durable, Safe, Multi-gene Lentiviral Vector Expression in Feline Trabecular Meshwork

(2007) Pranay D Khare et al.   MOLECULAR THERAPY