Article
Environmental Sciences
Jutta Fastner, Jonna Teikari, Anja Hoffmann, Antje Kohler, Sebastian Hoppe, Elke Dittmann, Martin Welker
Summary: Fatal dog poisoning in Tegeler See, Berlin, Germany, caused by neurotoxic cyanobacteria associated with aquatic macrophytes has raised concerns about human exposure, especially for children, to cyanotoxins during recreational activities. A study conducted from 2017 to 2021 analyzed 398 macrophyte samples and 463 water samples from bathing sites in 19 Berlin lakes, detecting cyanotoxins in 66% of macrophyte samples and 50% of water samples. Anatoxins were the most frequently detected toxin group in macrophyte samples (58%), while cylindrospermopsins were most prevalent in water samples (41%). The study also identified the presence of anatoxin-producing cyanobacteria in the water moss Fontinalis antipyretica. Based on toxicological evaluations, a critical anatoxin content of 3 μg/g fresh weight in macrophyte samples is proposed.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Food Science & Technology
Andrew D. Turner, Florence R. I. Turner, Martha White, David Hartnell, Claire G. Crompton, Nicola Bates, Jan Egginton, Liz Branscombe, Adam M. Lewis, Benjamin H. Maskrey
Summary: This article reports a case study of a dog's death at a freshwater reservoir in SW England. Analysis revealed that anatoxins were responsible for the rapid death of the dog, with these neurotoxins affecting the nervous system and causing rapid death.
Article
Chemistry, Medicinal
Miguel Baptista, Ana Catarina Braga, Rui Rosa, Pedro Reis Costa
Summary: This study investigated the presence of TTX in ocean sunfish samples from the South Portuguese coast and found no TTX was detected, indicating a non-existent or very limited risk of TTX poisoning.
Article
Marine & Freshwater Biology
Lucie Blahova, Ludek Sehnal, Olga Lepsova-Skacelova, Vendula Szmucova, Pavel Babica, Klara Hilscherova, Jonna Teikari, Kaarina Sivonen, Ludek Blaha
Summary: Water bloom-forming cyanobacteria have a significant impact on freshwater quality. This study focused on investigating the levels of ATX, CYN and their analogs in water blooms in the Czech Republic, and identified Raphidiopsis (Cylindrospermopsis) and Cuspidothrix as producers of CYN in Europe. Further research is needed to address the levels and hazards of ATX analogs due to their higher concentrations in laboratory strains.
Article
Environmental Sciences
Michal Adamski, Eliza Zimolag, Ariel Kaminski, Justyna Drukala, Jan Bialczyk
Summary: Cyanotoxins produced by cyanobacteria pose significant threats to human keratinocytes, inhibiting proliferation and migration, and causing cytotoxic effects. Among them, CYN and its decomposition products exhibit strong inhibitory effects on keratinocytes, while ANTX-a shows lower toxicity, requiring higher concentrations and longer exposure. Further research on cyanotoxins should focus on their decomposition products and ecotoxicology in natural aquatic environments.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Toxicology
Serkan Yilmaz, Taha Gokmen Ulger, Bayram Goktas, Sahlan Ozturk, Duygu Oztas Karatas, Ebru Beyzi
Summary: Cyanobacteria produce cyanotoxins, which are a global issue in water leading to environmental degradation and potential toxic effects on humans and animals. The main route of human exposure is through oral intake, increasing the risk to public health. This review focuses on the genotoxic effects of well-known cyanotoxins and their underlying mechanisms.
Article
Environmental Sciences
Ariel Kaminski, Christine Edwards, Ewelina Chrapusta-Srebrny, Linda A. Lawton
Summary: The study demonstrates that UV-A/TiO2 photocatalysis is effective in removing toxic substances such as ANTX-a and cyanobacterial cells, generating non-toxic decomposition products.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Plant Sciences
Bahareh Nowruzi, Adriana Sturion Lorenzi
Summary: The study found that heterocyst-forming cyanobacteria from Lavasan Lake may produce the neurotoxin homoanatoxin-a. By investigating isolated microcystins and homoanatoxin-a, it was discovered that only one isolate carried the gene for toxin production.
SOUTH AFRICAN JOURNAL OF BOTANY
(2021)
Article
Ecology
Kristel F. Sanchez, Baili Zhong, Jorge A. Agudelo, Meghan A. Duffy
Summary: Transmission of parasites from one host to another is essential for their survival. For some aquatic parasites, transmission occurs through a free-living stage in the water, waiting for a new host. This study found that although common cyanobacterial toxins did not affect parasite infectivity and growth, the duration of time spent in the water impacted the parasite's ability to successfully infect new hosts.
FRESHWATER BIOLOGY
(2023)
Article
Engineering, Environmental
Michal Saladyga, Malgorzata Kucala, Michal Adamski, Saravana Selvaraj, Ariel Kaminski
Summary: Phytoremediation is a useful method for removing cyanotoxins from water, but its efficacy is influenced by the composition of cyanobacterial mixtures. This study found that while some plants can effectively reduce intracellular toxins and cyanobacterial biomass, they can also cause an increase in toxin concentration in the medium.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2023)
Review
Environmental Sciences
Simon Colas, Benjamin Marie, Emilie Lance, Catherine Quiblier, Helene Tricoire-Leignel, Cesar Mattei
Summary: ATX-a, a neurotoxic alkaloid produced by freshwater cyanobacteria, can cause neurologic symptoms in humans following food poisoning and death in wild and domestic animals. While acute effects and mode of action have been studied, little is known about its potential chronic toxicity.
ENVIRONMENTAL RESEARCH
(2021)
Article
Cell Biology
Malgorzata Kucala, Michal Saladyga, Ariel Kaminski
Summary: Lemna trisulca showed potential as a phytoremediation agent for reducing cyanotoxin concentrations in water through co-cultivation with different species of cyanobacteria, affecting their growth and development, and stabilizing water conductivity and pH values.
Article
Environmental Sciences
Encarnacion Romera-Garcia, Rick Helmus, Ana Ballesteros-Gomez, Petra M. Visser
Summary: The increase in cyanobacterial blooms is linked to anthropogenic factors, causing concerns for drinking water companies and water managers due to the toxins produced. Simple, sensitive, and cost-effective analytical approaches are essential for risk assessment and large-scale studies. The development of a method for the multi-class determination of cyanotoxins in fresh water, which can separately report intra- and extracellular toxins, meets validation criteria and helps in risk management.
Review
Food Science & Technology
Pedro Reis Costa, Catarina Churro, Susana Margarida Rodrigues, Barbara Frazao, Miguel Barbosa, Lia Godinho, Lucia Solino, Viriato Timoteo, Neide Gouveia
Summary: This study reviews the occurrence of ciguatera cases in the Madeira Archipelago since its first detection in 2008, discusses the implemented risk management strategy, and provides a summary of the available data on the bioaccumulation of ciguatoxins (CTX) in the marine food web.
Article
Engineering, Environmental
Karina Yew-Hoong Gin, Zhi Yang Sim, Kwan Chien Goh, Jerome Wai Kit Kok, Shu Harn Te, Ngoc Han Tran, Wenxuan Li, Yiliang He
Summary: Picocyanobacteria are small cyanobacteria found in freshwater environments worldwide, known to cause harmful algal blooms. This study discovered that Synechococcus sp. can produce toxins, raising concerns about its toxicity in freshwater systems globally.
Review
Marine & Freshwater Biology
M. Chinain, C. M. Gatti, H. T. Darius, J-P Quod, P. A. Tester
Summary: Ciguatera Poisoning (CP) is the most prevalent seafood poisoning caused by ciguatoxins (CTXs) globally, primarily affecting carnivorous fish consumption. The highest incidence rates are reported in the Pacific and Caribbean regions, with an observed expansion of the geographical range of CP in recent years.
Article
Fisheries
Laure Vaitiare Andre, Simon Van Wynsberge, Mireille Chinain, Clemence Mahana Iti Gatti, Alexandra Dempsey, Serge Andrefouet
Summary: Millions of people depend on artisanal fisheries for their livelihoods, but fishers are increasingly facing ciguatera poisoning in many regions. Integrating ciguatera risk into systematic conservation plans can significantly improve prioritization solutions and reduce costs to fishers.
ICES JOURNAL OF MARINE SCIENCE
(2021)
Article
Marine & Freshwater Biology
Laura Biessy, Susanna A. Wood, Mireille Chinain, Melanie Roue, Kirsty F. Smith
Summary: The study used metabarcoding to characterize the taxonomic diversity of benthic marine cyanobacteria-dominated mats in the South Pacific. It found multiple potentially toxic cyanobacteria genera in these mats, with consistent core bacterial communities but significant differences between mats from different islands. The results emphasize the need for further research on the toxicity of these mats in the region.
Article
Environmental Sciences
Laure Vaitiare Andre, Simon Van Wynsberge, Mireille Chinain, Serge Andrefouet
Summary: SCP in Pacific Ocean Tropical Islands studies mainly focused on biodiversity representation objectives, with opportunity costs for fishers being the most frequent cost factor, and a transition from simple to complex scenarios to address climate change impacts. However, there are data quality issues and some island features are still being ignored.
MARINE POLLUTION BULLETIN
(2021)
Article
Chemistry, Analytical
Thomas Yon, Manoella Sibat, Damien Reveillon, Samuel Bertrand, Mireille Chinain, Philipp Hess
Summary: This study employed an experimental design approach to analyze Pacific ciguatoxins, finding that adjusting capillary voltage, sheath gas temperature, ion funnel low pressure voltage, and ion funnel exit voltage could significantly enhance the detection of toxins and gambierones. The optimized method was able to revisit the toxin profile of G. polynesiensis, confirming the presence of previously unreported compounds and detecting an isomer of CTX4A.
Article
Food Science & Technology
Isabel do Prado Leite, Khalil Sdiri, Angus Taylor, Jerome Viallon, Hela Ben Gharbia, Luiz Laureno Mafra Junior, Peter Swarzenski, Francois Oberhaensli, Helene Taiana Darius, Mireille Chinain, Marie-Yasmine Dechraoui Bottein
Summary: This study developed an experimental model to evaluate the trophic transfer of CTXs from herbivorous parrotfish to carnivorous lionfish. The results showed accumulation of CTXs in liver tissues of lionfish during exposure, with slow toxin elimination during depuration. these preliminary findings provide insights into CTX transfer and kinetics along the food web, warranting further research in adult lionfish.
Article
Food Science & Technology
Clemence Mahana Iti Gatti, Kiyojiken Chung, Erwan Oehler, T. J. Pierce, Matthew O. Gribble, Mireille Chinain
Summary: This study analyzed medical files of 49 patients to better understand chronic ciguatera manifestations and identify potential predictive factors for their duration. The study found age, tobacco consumption, acute bradycardia, laboratory measures of urea, and neutrophils to be significant predictors of symptoms lasting >= 3 months. This exploratory study contributes to the development of ciguatera epidemiology by narrowing down the predictors worth further investigation.
Article
Chemistry, Medicinal
Helene Taiana Darius, Taina Revel, Philippe Cruchet, Jerome Viallon, Clemence Mahana iti Gatti, Manoella Sibat, Philipp Hess, Mireille Chinain
Summary: In 2003, cases of ciguatera poisoning linked to the consumption of deep-water fish occurred in the Gambier Islands, French Polynesia. A study in 2004 found significant levels of ciguatoxins in deep-sea fish samples, leading to the discovery that deep-water fish may act as potential vectors for ciguatera poisoning. This highlights the importance of systematic monitoring of ciguatoxins in all exploited fish species, especially in hotspots like the Gambier Islands.
Article
Chemistry, Medicinal
Helene Taiana Darius, Christelle Paillon, Gerard Mou-Tham, Andre Ung, Philippe Cruchet, Taina Revel, Jerome Viallon, Laurent Vigliola, Dominique Ponton, Mireille Chinain
Summary: The size, weight, age, and growth of fish are not reliable determinants of ciguatoxicity. Larger fish pose an increased risk of poisoning, but even small or low-weight fish can still be toxic.
Article
Chemistry, Medicinal
Helene Taiana Darius, Taina Revel, Jerome Viallon, Manoella Sibat, Philippe Cruchet, Sebastien Longo, Donnie Ransom Hardison, William C. Holland, Patricia A. Tester, R. Wayne Litaker, Jennifer R. McCall, Philipp Hess, Mireille Chinain
Summary: This study compared the performance of three methods for quantifying ciguatoxins (CTXs) in Gambierdiscus polynesiensis. The results showed significant correlations between the fluorescent receptor binding assay (fRBA), neuroblastoma cell-based assay (CBA-N2a), and liquid chromatography tandem mass spectrometry (LC-MS/MS). The CBA-N2a was found to be the most sensitive, while all assays exhibited good repeatability. The combined use of fRBA and/or CBA-N2a for screening and LC-MS/MS for confirmation can efficiently evaluate CTX in Gambierdiscus.
Article
Environmental Sciences
Laure Vaitiare Andre, Mireille Chinain, Clemence M. Gatti, Vetea Liao, Simon Van Wynsberge, Pauline Tedesco, Serge Andrefouet
Summary: Oyster farming for black pearl production is a crucial industry in French Polynesia, but has been facing crises recently. An option to revive the industry is to reintroduce oysters in strategic benthic locations, promoting recolonization and spat collection. This approach provides managers with a portfolio of restocking options.
MARINE POLLUTION BULLETIN
(2022)
Article
Green & Sustainable Science & Technology
Laure Vaitiare Andre, Simon Van Wynsberge, Mireille Chinain, Clemence Mahana Iti Gatti, Vetea Liao, Serge Andrefouet
Summary: Exploring diversification options can provide tailor-made plans for local managers to adapt to island development questions, reducing dependence on external factors and increasing population resilience to global changes.
Article
Marine & Freshwater Biology
Jacqui Stuart, Kirsty F. Smith, Lesley Rhodes, J. Sam Murray, Jerome Viallon, Kevin Henry, H. Taiana Darius, Shauna A. Murray, Caroline Dornelles De Azevedo, Phoebe Argyle, Mireille Chinain
Summary: This study aims to further characterize G. honu by assessing its distribution, intraspecific genetic variation, toxicity, and toxin production. The results indicate that G. honu is widely distributed in the Pacific region with no significant intraspecific population structure, and the toxicity diversity is not correlated with geographical patterns.
Article
Fisheries
Laure Vaitiare Andre, Simon Van Wynsberge, Mireille Chinain, Serge Andrefouet
Summary: Traditional fishery management schemes have gained recognition worldwide, but the changing environmental and socio-economic contexts require adjustments. This study examines a traditional system on a Polynesian island and suggests a hybrid design combining traditional practices and data-based optimizations.
FISHERIES RESEARCH
(2022)
Article
Environmental Sciences
Gustaaf M. Hallegraeff, Donald M. Anderson, Catherine Belin, Marie-Yasmine Dechraoui Bottein, Eileen Bresnan, Mireille Chinain, Henrik Enevoldsen, Mitsunori Iwataki, Bengt Karlson, Cynthia H. McKenzie, Ines Sunesen, Grant C. Pitcher, Pieter Provoost, Anthony Richardson, Laura Schweibold, Patricia A. Tester, Vera L. Trainer, Aletta T. Yniguez, Adriana Zingone
Summary: According to an analysis of global harmful algal bloom events, it was found that there is no uniform increase in the global occurrence of these events over time. The recorded increase in events is primarily due to enhanced coastal monitoring and aquaculture practices.
COMMUNICATIONS EARTH & ENVIRONMENT
(2021)
Article
Pharmacology & Pharmacy
Mohammadhossein Movassaghghazani, Nazanin Shabansalmani
Summary: The study revealed high levels of AFM1 in both breast milk and powdered milk samples in Tehran, with some samples exceeding the established limits. Therefore, monitoring and regulating toxin levels in these products is crucial for maternal and infant health.
Article
Pharmacology & Pharmacy
Defeng Wen, Wantong Han, Quan Chen, Guanhui Qi, Mengling Gao, Pu Guo, Yu Liu, Zhongyuan Wu, Shulin Fu, Qirong Lu, Yinsheng Qiu
Summary: Luteolin can inhibit FB1-induced intestinal inflammatory injury by inhibiting the activation of NF-kappa B and ERK signaling pathways, according to network pharmacology and in vitro experiments.
