Synergy of Omeprazole and Praziquantel In Vitro Treatment against Schistosoma mansoni Adult Worms

Human schistosomiasis

(2014) Daniel G Colley et al.   LANCET

Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel

(2014) Ravi S. Kasinathan et al.   PLoS Neglected Tropical Diseases

Regulation of Schistosoma mansoni Development and Reproduction by the Mitogen-Activated Protein Kinase Signaling Pathway

(2014) Luiza Freire de Andrade et al.   PLoS Neglected Tropical Diseases

Schistosome ABC multidrug transporters: From pharmacology to physiology

(2014) Robert M. Greenberg   International Journal for Parasitology-Drugs and Drug Resistance

New approaches for understanding mechanisms of drug resistance in schistosomes

(2013) ROBERT M. GREENBERG   PARASITOLOGY

Praziquantel Treatment Decreases Schistosoma mansoni Genetic Diversity in Experimental Infections

(2013) Regina Coeli et al.   PLoS Neglected Tropical Diseases

Transcriptional Responses of In Vivo Praziquantel Exposure in Schistosomes Identifies a Functional Role for Calcium Signalling Pathway Member CamKII

(2013) Hong You et al.   PLoS Pathogens

Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni

(2013) Vanessa Dufour et al.   PLoS Pathogens

Genome-wide identification and characterization of a panel of house-keeping genes in Schistosoma japonicum

(2012) Shuai Liu et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Transcriptional analysis of Schistosoma mansoni treated with praziquantel in vitro

(2012) Jarrett Hines-Kay et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The biology and therapeutic targeting of the proprotein convertases

(2012) Nabil G. Seidah et al.   NATURE REVIEWS DRUG DISCOVERY

Liver-stage malaria parasites vulnerable to diverse chemical scaffolds

(2012) E. R. Derbyshire et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Systematically Improved High Quality Genome and Transcriptome of the Human Blood Fluke Schistosoma mansoni

(2012) Anna V. Protasio et al.   PLoS Neglected Tropical Diseases

Antiprotozoal activity of proton-pump inhibitors

(2011) Jaime Pérez-Villanueva et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A 24-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study of the Efficacy of Oral SCIO-469, a p38 Mitogen-activated Protein Kinase Inhibitor, in Patients with Active Rheumatoid Arthritis

(2011) MARK C. GENOVESE et al.   JOURNAL OF RHEUMATOLOGY

Glutamate-mediated signaling in Schistosoma mansoni: A novel glutamate receptor is expressed in neurons and the female reproductive tract

(2010) Amira Taman et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

(2010) Emily Peak et al.   PLoS Neglected Tropical Diseases

Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel

(2009) Ravi S. Kasinathan et al.   FASEB JOURNAL

Exposed proteins of the Schistosoma japonicum tegument

(2009) Jason Mulvenna et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

A Comparative Chemogenomics Strategy to Predict Potential Drug Targets in the Metazoan Pathogen, Schistosoma mansoni

(2009) Conor R. Caffrey et al.   PLoS One

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

(2009) Sandra D. Melman et al.   PLoS Neglected Tropical Diseases

Praziquantel Affects the Regulatory Myosin Light Chain of Schistosoma mansoni

(2008) M. Gnanasekar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders

(2008) Kimberly R. Byrnes et al.   Neurotherapeutics