Inhibition or Knockdown of ABC Transporters Enhances Susceptibility of Adult and Juvenile Schistosomes to Praziquantel

Design and synthesis of molecular probes for the determination of the target of the anthelmintic drug praziquantel

(2014) Lalit Kumar Sharma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Schistosoma mansoni: a method for inducing resistance to praziquantel using infected Biomphalaria glabrata snails

(2014) Flávia FB Couto et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Diagnosis of Schistosoma mansoni without the Stool: Comparison of Three Diagnostic Tests to Detect Schiostosoma mansoni Infection from Filtered Urine in Zambia

(2013) Nilanjan Lodh et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

New approaches for understanding mechanisms of drug resistance in schistosomes

(2013) ROBERT M. GREENBERG   PARASITOLOGY

Transport proteins of the ABC systems superfamily and their role in drug action and resistance in nematodes

(2013) Bernadette F. Ardelli   PARASITOLOGY INTERNATIONAL

ABC multidrug transporters in schistosomes and other parasitic flatworms

(2013) Robert M. Greenberg   PARASITOLOGY INTERNATIONAL

Comparative efficacy of one versus two doses of praziquantel on cure rate of Schistosoma mansoni infection and re-infection in Mayuge District, Uganda

(2013) Edridah M. Tukahebwa et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Effect of the P-glycoprotein inhibitor, R(+)-verapamil on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica

(2013) J. Savage et al.   VETERINARY PARASITOLOGY

Transcriptional analysis of Schistosoma mansoni treated with praziquantel in vitro

(2012) Jarrett Hines-Kay et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

The P-glycoprotein multidrug transporter

(2011) Frances J. Sharom   Essays in Biochemistry

Pharmacology and potential physiological significance of schistosome multidrug resistance transporters

(2011) Ravi S. Kasinathan et al.   EXPERIMENTAL PARASITOLOGY

Genetic Knockdown and Pharmacological Inhibition of Parasite Multidrug Resistance Transporters Disrupts Egg Production in Schistosoma mansoni

(2011) Ravi S. Kasinathan et al.   PLoS Neglected Tropical Diseases

Schistosoma haematobium Treatment in 1–5 Year Old Children: Safety and Efficacy of the Antihelminthic Drug Praziquantel

(2011) Francisca Mutapi et al.   PLoS Neglected Tropical Diseases

Resolution of Praziquantel

(2011) Michael Woelfle et al.   PLoS Neglected Tropical Diseases

The “Specific” P-Glycoprotein Inhibitor Tariquidar Is Also a Substrate and an Inhibitor for Breast Cancer Resistance Protein (BCRP/ABCG2)

(2010) Pavitra Kannan et al.   ACS Chemical Neuroscience

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Schistosomiasis elimination: lessons from the past guide the future

(2010) Darren J Gray et al.   LANCET INFECTIOUS DISEASES

Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel

(2010) Ravi S. Kasinathan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Small-Molecule Multidrug Resistance-Associated Protein 1 Inhibitor Reversan Increases the Therapeutic Index of Chemotherapy in Mouse Models of Neuroblastoma

(2009) C. A. Burkhart et al.   CANCER RESEARCH

Transport of lipids by ABC proteins: Interactions and implications for cellular toxicity, viability and function

(2009) Irving L.M.H. Aye et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel

(2009) Ravi S. Kasinathan et al.   FASEB JOURNAL

ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer

(2009) Rieneke van de Ven et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Schistosoma mansoni P-glycoprotein levels increase in response to praziquantel exposure and correlate with reduced praziquantel susceptibility

(2009) Shanta M. Messerli et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Drug resistance mechanisms in helminths: is it survival of the fittest?

(2009) Catherine E. James et al.   TRENDS IN PARASITOLOGY

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

(2009) Sandra D. Melman et al.   PLoS Neglected Tropical Diseases

Schistosomiasis in Africa: An Emerging Tragedy in Our New Global Health Decade

(2009) Peter J. Hotez et al.   PLoS Neglected Tropical Diseases

CellTrack: an open-source software for cell tracking and motility analysis

(2008) A. Sacan et al.   BIOINFORMATICS

Two-year impact of single praziquantel treatment on infection in the national control programme on schistosomiasis in Burkina Faso

(2008) Seydou Toure   BULLETIN OF THE WORLD HEALTH ORGANIZATION

Genuine Functions of P-Glycoprotein (ABCB1)

(2008) Takaharu Mizutani et al.   CURRENT DRUG METABOLISM

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Towards an understanding of the mechanism of action of praziquantel

(2008) Anthony D. Aragon et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Routine Kato–Katz technique underestimates the prevalence of Schistosoma japonicum: A case study in an endemic area of the People's Republic of China

(2008) Dan-Dan Lin et al.   PARASITOLOGY INTERNATIONAL

ABC transporter modulation: a strategy to enhance the activity of macrocyclic lactone anthelmintics

(2008) Anne Lespine et al.   TRENDS IN PARASITOLOGY