Synergistic Interactions between Drosophila Orthologues of Genes Spanned by De Novo Human CNVs Support Multiple-Hit Models of Autism

The Familial Risk of Autism

(2014) Sven Sandin et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Roles of FMRP-Regulated Genes in Autism Spectrum Disorder: Single- and Multiple-Hit Genetic Etiologies

(2013) Julia Steinberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The 22q11.2 Deletion Syndrome as a Window into Complex Neuropsychiatric Disorders Over the Lifespan

(2013) Rachel K. Jonas et al.   BIOLOGICAL PSYCHIATRY

Shank3 Deficiency Induces NMDA Receptor Hypofunction via an Actin-Dependent Mechanism

(2013) L. J. Duffney et al.   JOURNAL OF NEUROSCIENCE

CNVs conferring risk of autism or schizophrenia affect cognition in controls

(2013) Hreinn Stefansson et al.   NATURE

Progress toward treatments for synaptic defects in autism

(2013) Richard Delorme et al.   NATURE MEDICINE

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

(2013) Trudy F. C. Mackay   NATURE REVIEWS GENETICS

The Database of Genomic Variants: a curated collection of structural variation in the human genome

(2013) Jeffrey R. MacDonald et al.   NUCLEIC ACIDS RESEARCH

Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486

(2013) B. M. Dolan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila

(2013) Merel A. W. Oortveld et al.   PLoS Genetics

Network Topologies and Convergent Aetiologies Arising from Deletions and Duplications Observed in Individuals with Autism

(2013) Hyun Ji Noh et al.   PLoS Genetics

Drosophila Neuroligin 2 is Required Presynaptically and Postsynaptically for Proper Synaptic Differentiation and Synaptic Transmission

(2012) Y.-C. Chen et al.   JOURNAL OF NEUROSCIENCE

Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts

(2012) D Moreno-De-Luca et al.   MOLECULAR PSYCHIATRY

Autism-related deficits via dysregulated eIF4E-dependent translational control

(2012) Christos G. Gkogkas et al.   NATURE

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

(2012) Brian J. O’Roak et al.   NATURE

TOR Is Required for the Retrograde Regulation of Synaptic Homeostasis at the Drosophila Neuromuscular Junction

(2012) Jay Penney et al.   NEURON

MicroRNAs in neuronal function and dysfunction

(2012) Heh-In Im et al.   TRENDS IN NEUROSCIENCES

CULLIN-3 Controls TIMELESS Oscillations in the Drosophila Circadian Clock

(2012) Brigitte Grima et al.   PLOS BIOLOGY

Common genetic variants, acting additively, are a major source of risk for autism

(2012) Lambertus Klei et al.   Molecular Autism

Evidence for broader autism phenotype characteristics in parents from multiple-incidence autism families

(2011) Raphael Bernier et al.   Autism Research

Drosophila strategies to study psychiatric disorders

(2011) Bart van Alphen et al.   BRAIN RESEARCH BULLETIN

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Neurexins and neuroligins: synapses look out of the nervous system

(2011) Alessia Bottos et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Synapse development in health and disease

(2011) Jan Elizabeth Melom et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Drosophila modeling of heritable neurodevelopmental disorders

(2011) Cheryl L Gatto et al.   CURRENT OPINION IN NEUROBIOLOGY

A simple assay to study social behavior inDrosophila: measurement of social space within a group1

(2011) A. F. Simon et al.   GENES BRAIN AND BEHAVIOR

Neurexins and Neuroligins: Recent Insights from Invertebrates

(2011) David Knight et al.   MOLECULAR NEUROBIOLOGY

Rare structural variation of synapse and neurotransmission genes in autism

(2011) X Gai et al.   MOLECULAR PSYCHIATRY

insomniac and Cullin-3 Regulate Sleep and Wakefulness in Drosophila

(2011) Nicholas Stavropoulos et al.   NEURON

Hts/Adducin Controls Synaptic Elaboration and Elimination

(2011) Jan Pielage et al.   NEURON

Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders

(2011) Dan Levy et al.   NEURON

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

Multiple Recurrent De Novo CNVs, Including Duplications of the 7q11.23 Williams Syndrome Region, Are Strongly Associated with Autism

(2011) Stephan J. Sanders et al.   NEURON

Survival Motor Neuron Protein Regulates Stem Cell Division, Proliferation, and Differentiation in Drosophila

(2011) Stuart J. Grice et al.   PLoS Genetics

Etiological heterogeneity in autism spectrum disorders: More than 100 genetic and genomic disorders and still counting

(2010) Catalina Betancur   BRAIN RESEARCH

CAST and ELKS proteins: structural and functional determinants of the presynaptic active zone

(2010) Y. Hida et al.   JOURNAL OF BIOCHEMISTRY

Functional impact of global rare copy number variation in autism spectrum disorders

(2010) Dalila Pinto et al.   NATURE

Discovery of common Asian copy number variants using integrated high-resolution array CGH and massively parallel DNA sequencing

(2010) Hansoo Park et al.   NATURE GENETICS

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

(2010) Dieter Edbauer et al.   NEURON

Neurexin in Embryonic Drosophila Neuromuscular Junctions

(2010) Kaiyun Chen et al.   PLoS One

Sleep in children with autistic spectrum disorder

(2010) Flavia Cortesi et al.   SLEEP MEDICINE

CNTNAP2 and NRXN1 Are Mutated in Autosomal-Recessive Pitt-Hopkins-like Mental Retardation and Determine the Level of a Common Synaptic Protein in Drosophila

(2009) Christiane Zweier et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The role of rare structural variants in the genetics of autism spectrum disorders

(2009) M. Kusenda et al.   CYTOGENETIC AND GENOME RESEARCH

Drosophila Neurexin IV stabilizes neuron-glia interactions at the CNS midline by binding to Wrapper

(2009) T. Stork et al.   DEVELOPMENT

Regulation of glutamate receptor subunit availability by microRNAs

(2009) Julie Karr et al.   JOURNAL OF CELL BIOLOGY

Notch Signaling Is Required for Activity-Dependent Synaptic Plasticity at theDrosophilaNeuromuscular Junction

(2009) Benjamin Lovegren de Bivort et al.   JOURNAL OF NEUROGENETICS

microRNAs at the synapse

(2009) Gerhard Schratt   NATURE REVIEWS NEUROSCIENCE

Circadian rhythms and sleep in children with autism

(2009) Gena Glickman   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic interaction between Neurexin and CAKI/CMG is important for synaptic function in Drosophila neuromuscular junction

(2009) Mingkuan Sun et al.   NEUROSCIENCE RESEARCH

Structural Variation of Chromosomes in Autism Spectrum Disorder

(2008) Christian R. Marshall et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic counseling for the 22q11.2 deletion

(2008) Donna M. McDonald-McGinn et al.   Developmental Disabilities Research Reviews

The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches

(2008) Y. Lu et al.   HUMAN MOLECULAR GENETICS

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

A Drosophila model for Angelman syndrome

(2008) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA