Human Intellectual Disability Genes Form Conserved Functional Modules in Drosophila

CEP89 is required for mitochondrial metabolism and neuronal function in man and fly

(2013) Bregje W.M. van Bon et al.   HUMAN MOLECULAR GENETICS

GATAD2Bloss-of-function mutations cause a recognisable syndrome with intellectual disability and are associated with learning deficits and synaptic undergrowth inDrosophila

(2013) Marjolein H Willemsen et al.   JOURNAL OF MEDICAL GENETICS

Genetics and molecular basis of human peroxisome biogenesis disorders

(2012) Hans R. Waterham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Arl13b in Primary Cilia Regulates the Migration and Placement of Interneurons in the Developing Cerebral Cortex

(2012) Holden Higginbotham et al.   DEVELOPMENTAL CELL

A shared molecular mechanism underlies the human rasopathies Legius syndrome and Neurofibromatosis-1

(2012) I. B. Stowe et al.   GENES & DEVELOPMENT

Cohesin controls planar cell polarity by regulating the level of the seven-pass transmembrane cadherin Flamingo

(2012) Kousuke Mouri et al.   GENES TO CELLS

A broad expression profile of the GMR-GAL4 driver in Drosophila melanogaster

(2012) W.-Z. Li et al.   GENETICS AND MOLECULAR RESEARCH

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Genetic and Epigenetic Networks in Intellectual Disabilities

(2011) Hans van Bokhoven   Annual Review of Genetics

A Protein Complex Network of Drosophila melanogaster

(2011) K.G. Guruharsha et al.   CELL

Genome-Wide Analysis of Self-Renewal in Drosophila Neural Stem Cells by Transgenic RNAi

(2011) Ralph A. Neumüller et al.   Cell Stem Cell

Drosophila modeling of heritable neurodevelopmental disorders

(2011) Cheryl L Gatto et al.   CURRENT OPINION IN NEUROBIOLOGY

CYFIP dependent Actin Remodeling controls specific aspects of Drosophila eye morphogenesis

(2011) Anne Galy et al.   DEVELOPMENTAL BIOLOGY

Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity

(2011) Ryan S. Gray et al.   DEVELOPMENTAL CELL

Emerging major synaptic signaling pathways involved in intellectual disability

(2011) A Pavlowsky et al.   MOLECULAR PSYCHIATRY

Transcriptome profiling of UPF3B/NMD-deficient lymphoblastoid cells from patients with various forms of intellectual disability

(2011) L S Nguyen et al.   MOLECULAR PSYCHIATRY

Deep sequencing reveals 50 novel genes for recessive cognitive disorders

(2011) Hossein Najmabadi et al.   NATURE

A transition zone complex regulates mammalian ciliogenesis and ciliary membrane composition

(2011) Francesc R Garcia-Gonzalo et al.   NATURE GENETICS

Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses

(2011) Sarah R. Gilman et al.   NEURON

The Cambrian Conundrum: Early Divergence and Later Ecological Success in the Early History of Animals

(2011) D. H. Erwin et al.   SCIENCE

Epigenetic Regulation of Learning and Memory by Drosophila EHMT/G9a

(2011) Jamie M. Kramer et al.   PLOS BIOLOGY

DNA Damage, Somatic Aneuploidy, and Malignant Sarcoma Susceptibility in Muscular Dystrophies

(2011) Wolfgang M. Schmidt et al.   PLoS Genetics

Genetics of Early Onset Cognitive Impairment

(2010) Hans Hilger Ropers   Annual Review of Genomics and Human Genetics

Toward Fulfilling the Promise of Molecular Medicine in Fragile X Syndrome

(2010) Dilja D. Krueger et al.   Annual Review of Medicine

Measuring the physical cohesiveness of proteins using physical interaction enrichment

(2010) Iziah Edwin Sama et al.   BIOINFORMATICS

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

ExprEssence - Revealing the essence of differential experimental data in the context of an interaction/regulation net-work

(2010) Gregor Warsow et al.   BMC Systems Biology

Building and analyzing protein interactome networks by cross-species comparisons

(2010) Amy M Wiles et al.   BMC Systems Biology

A SP1/MIZ1/MYCN Repression Complex Recruits HDAC1 at theTRKAandp75NTRPromoters and Affects Neuroblastoma Malignancy by Inhibiting the Cell Response to NGF

(2010) Nunzio Iraci et al.   CANCER RESEARCH

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice

(2010) Setsu Endoh-Yamagami et al.   DEVELOPMENTAL BIOLOGY

Fruit flies and intellectual disability

(2010) Francois V. Bolduc et al.   FLY

CDK19 is disrupted in a female patient with bilateral congenital retinal folds, microcephaly and mild mental retardation

(2010) Arijit Mukhopadhyay et al.   HUMAN GENETICS

Kismet/CHD7 regulates axon morphology, memory and locomotion in a Drosophila model of CHARGE syndrome

(2010) David J. Melicharek et al.   HUMAN MOLECULAR GENETICS

WhyDrosophilato Study Phototransduction?

(2010) William L. Pak   JOURNAL OF NEUROGENETICS

Systematic genetic analysis of muscle morphogenesis and function in Drosophila

(2010) Frank Schnorrer et al.   NATURE

Characterization of the proteome, diseases and evolution of the human postsynaptic density

(2010) Àlex Bayés et al.   NATURE NEUROSCIENCE

Phenomics: the next challenge

(2010) David Houle et al.   NATURE REVIEWS GENETICS

100 years of Drosophila research and its impact on vertebrate neuroscience: a history lesson for the future

(2010) Hugo J. Bellen et al.   NATURE REVIEWS NEUROSCIENCE

DroID 2011: a comprehensive, integrated resource for protein, transcription factor, RNA and gene interactions for Drosophila

(2010) Thilakam Murali et al.   NUCLEIC ACIDS RESEARCH

Systematic discovery of nonobvious human disease models through orthologous phenotypes

(2010) K. L. McGary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE

(2010) et al.   SCIENCE

The Biological Coherence of Human Phenome Databases

(2009) Martin Oti et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Tumor suppressors and cell metabolism: a recipe for cancer growth

(2009) R. G. Jones et al.   GENES & DEVELOPMENT

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

SLC29A3 gene is mutated in pigmented hypertrichosis with insulin-dependent diabetes mellitus syndrome and interacts with the insulin signaling pathway

(2009) Simon T. Cliffe et al.   HUMAN MOLECULAR GENETICS

Upregulation of myosin Va by Snail is involved in cancer cell migration and metastasis

(2009) Linxiang Lan et al.   INTERNATIONAL JOURNAL OF CANCER

Adult reversal of cognitive phenotypes in neurodevelopmental disorders

(2009) Alcino J. Silva et al.   Journal of Neurodevelopmental Disorders

The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse

(2009) Gonneke S. K. Pilgram et al.   MOLECULAR NEUROBIOLOGY

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

(2009) Jennifer L. Mummery-Widmer et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Phenomics: the systematic study of phenotypes on a genome-wide scale

(2009) R.M. Bilder et al.   NEUROSCIENCE

Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development

(2009) H. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tubulin-related cortical dysgeneses: microtubule dysfunction underlying neuronal migration defects

(2009) Xavier H. Jaglin et al.   TRENDS IN GENETICS

Oligosaccharyltransferase-Subunit Mutations in Nonsyndromic Mental Retardation

(2008) Florence Molinari et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CC2D2A Is Mutated in Joubert Syndrome and Interacts with the Ciliopathy-Associated Basal Body Protein CEP290

(2008) Nicholas T. Gorden et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Human Phenotype Ontology: A Tool for Annotating and Analyzing Human Hereditary Disease

(2008) Peter N. Robinson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

DroID: the Drosophila Interactions Database, a comprehensive resource for annotated gene and protein interactions

(2008) Jingkai Yu et al.   BMC GENOMICS

Identification of human haploinsufficient genes and their genomic proximity to segmental duplications

(2008) Vinh T Dang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

The Drosophila homologue of the Angelman syndrome ubiquitin ligase regulates the formation of terminal dendritic branches

(2008) Y. Lu et al.   HUMAN MOLECULAR GENETICS

Reversing Neurodevelopmental Disorders in Adults

(2008) Dan Ehninger et al.   NEURON

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Human Protein Reference Database--2009 update

(2008) T. S. Keshava Prasad et al.   NUCLEIC ACIDS RESEARCH

FlyBase: enhancing Drosophila Gene Ontology annotations

(2008) S. Tweedie et al.   NUCLEIC ACIDS RESEARCH

Phenome connections

(2008) Martin Oti et al.   TRENDS IN GENETICS

Oncogenes on my mind: ERK and MTOR signaling in cognitive diseases

(2008) Lianne C. Krab et al.   TRENDS IN GENETICS

Semaphorin3A regulates axon growth independently of growth cone repulsion via modulation of TrkA signaling

(2007) A. Ben-Zvi et al.   CELLULAR SIGNALLING