Imputation of the Rare HOXB13 G84E Mutation and Cancer Risk in a Large Population-Based Cohort

Statistical power and significance testing in large-scale genetic studies

(2014) Pak C. Sham et al.   NATURE REVIEWS GENETICS

Fine-Mapping the HOXB Region Detects Common Variants Tagging a Rare Coding Allele: Evidence for Synthetic Association in Prostate Cancer

(2014) Edward J. Saunders et al.   PLoS Genetics

Imputation of coding variants in African Americans: better performance using data from the exome sequencing project

(2013) Qing Duan et al.   BIOINFORMATICS

Germline HOXB13 p.Gly84Glu mutation and risk of colorectal cancer

(2013) Mohammad R. Akbari et al.   Cancer Epidemiology

HOXB13 Mutation and Prostate Cancer: Studies of Siblings and Aggressive Disease

(2013) J. S. Witte et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

HOXB13 G84E Mutation in Finland: Population-Based Analysis of Prostate, Breast, and Colorectal Cancer Risk

(2013) V. H. Laitinen et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

The G84E mutation of HOXB13 is associated with increased risk for prostate cancer: results from the REDUCE trial

(2013) Z. Chen et al.   CARCINOGENESIS

Germline Homeobox B13 (HOXB13) G84E Mutation and Prostate Cancer Risk in European Descendants: A Meta-analysis of 24 213 Cases and 73 631 Controls

(2013) Zhiqun Shang et al.   EUROPEAN UROLOGY

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

PP076

(2013) Rocco Sabatino et al.   ORAL ONCOLOGY

Population-Based Estimate of Prostate Cancer Risk for Carriers of the HOXB13 Missense Mutation G84E

(2013) Robert J. MacInnis et al.   PLoS One

Imputation of Variants from the 1000 Genomes Project Modestly Improves Known Associations and Can Identify Low-frequency Variant - Phenotype Associations Undetected by HapMap Based Imputation

(2013) Andrew R. Wood et al.   PLoS One

Local Exome Sequences Facilitate Imputation of Less Common Variants and Increase Power of Genome Wide Association Studies

(2013) Peter K. Joshi et al.   PLoS One

The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland

(2013) Wojciech Kluźniak et al.   PROSTATE

G84E mutation in HOXB13 is firmly associated with prostate cancer risk: a meta-analysis

(2013) Hang Huang et al.   TUMOR BIOLOGY

Imputation of Exome Sequence Variants into Population- Based Samples and Blood-Cell-Trait-Associated Loci in African Americans: NHLBI GO Exome Sequencing Project

(2012) Paul L. Auer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Subset-Based Approach Improves Power and Interpretation for the Combined Analysis of Genetic Association Studies of Heterogeneous Traits

(2012) Samsiddhi Bhattacharjee et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Confirmation of the HOXB13 G84E Germline Mutation in Familial Prostate Cancer

(2012) J. P. Breyer et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A Population-based Assessment of Germline HOXB13 G84E Mutation and Prostate Cancer Risk

(2012) Robert Karlsson et al.   EUROPEAN UROLOGY

Genotype Imputation of MetabochipSNPs Using a Study-Specific Reference Panel of ∼4,000 Haplotypes in African Americans From the Women's Health Initiative

(2012) Eric Yi Liu et al.   GENETIC EPIDEMIOLOGY

A Coalescent Model for Genotype Imputation

(2012) E. M. Jewett et al.   GENETICS

Effect of Genome-Wide Genotyping and Reference Panels on Rare Variants Imputation

(2012) Hou-Feng Zheng et al.   Journal of Genetics and Genomics

Association Between Germline HOXB13 G84E Mutation and Risk of Prostate Cancer

(2012) M. R. Akbari et al.   JNCI-Journal of the National Cancer Institute

A study based on whole-genome sequencing yields a rare variant at 8q24 associated with prostate cancer

(2012) Julius Gudmundsson et al.   NATURE GENETICS

Fast and accurate genotype imputation in genome-wide association studies through pre-phasing

(2012) Bryan Howie et al.   NATURE GENETICS

Association of aHOXB13Variant with Breast Cancer

(2012) Shaheen Alanee et al.   NEW ENGLAND JOURNAL OF MEDICINE

Germline Mutations inHOXB13and Prostate-Cancer Risk

(2012) Charles M. Ewing et al.   NEW ENGLAND JOURNAL OF MEDICINE

HOXB13mutations in a population-based, case-control study of prostate cancer

(2012) Marni Stott-Miller et al.   PROSTATE

Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets

(2011) Luke Jostins et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Design and coverage of high throughput genotyping arrays optimized for individuals of East Asian, African American, and Latino race/ethnicity using imputation and a novel hybrid SNP selection algorithm

(2011) Thomas J. Hoffmann et al.   GENOMICS

Next generation genome-wide association tool: Design and coverage of a high-throughput European-optimized SNP array

(2011) Thomas J. Hoffmann et al.   GENOMICS

Performance of Genotype Imputations Using Data from the 1000 Genomes Project

(2011) Yun Ju Sung et al.   HUMAN HEREDITY

A rare variant in MYH6 is associated with high risk of sick sinus syndrome

(2011) Hilma Holm et al.   NATURE GENETICS

A linear complexity phasing method for thousands of genomes

(2011) Olivier Delaneau et al.   NATURE METHODS

Performance of Genotype Imputation for Rare Variants Identified in Exons and Flanking Regions of Genes

(2011) Li Li et al.   PLoS One

Genotype Imputation with Thousands of Genomes

(2011) Bryan Howie et al.   G3-Genes Genomes Genetics

Genotype imputation for genome-wide association studies

(2010) Jonathan Marchini et al.   NATURE REVIEWS GENETICS

Uncovering the roles of rare variants in common disease through whole-genome sequencing

(2010) Elizabeth T. Cirulli et al.   NATURE REVIEWS GENETICS

Rare Variants Create Synthetic Genome-Wide Associations

(2010) Samuel P. Dickson et al.   PLOS BIOLOGY

Genotype-Imputation Accuracy across Worldwide Human Populations

(2009) Lucy Huang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Fast model-based estimation of ancestry in unrelated individuals

(2009) D. H. Alexander et al.   GENOME RESEARCH

The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens

(2009) John D. Norris et al.   MOLECULAR CELL

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Worldwide Human Relationships Inferred from Genome-Wide Patterns of Variation

(2008) J. Z. Li et al.   SCIENCE