Lead Exposure Disrupts Global DNA Methylation in Human Embryonic Stem Cells and Alters Their Neuronal Differentiation

Alzheimer’s Disease Biomarkers and Epigenetic Intermediates Following Exposure to Pb In Vitro

(2014) Syed Waseem Bihaqi et al.   Current Alzheimer Research

A-clustering: a novel method for the detection of co-regulated methylation regions, and regions associated with exposure

(2013) Tamar Sofer et al.   BIOINFORMATICS

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

Epigenomic Analysis of Multilineage Differentiation of Human Embryonic Stem Cells

(2013) Wei Xie et al.   CELL

Lead Induces Similar Gene Expression Changes in Brains of Gestationally Exposed Adult Mice and in Neurons Differentiated from Mouse Embryonic Stem Cells

(2013) Francisco Javier Sánchez-Martín et al.   PLoS One

Defining the Diversity of Phenotypic Respecification Using Multiple Cell Lines and Reprogramming Regimens

(2013) Bradly Alicea et al.   STEM CELLS AND DEVELOPMENT

IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data

(2012) D. Wang et al.   BIOINFORMATICS

Evaluation of Developmental Toxicants and Signaling Pathways in a Functional Test Based on the Migration of Human Neural Crest Cells

(2012) Bastian Zimmer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Prenatal Lead Levels, Plasma Amyloid β Levels, and Gene Expression in Young Adulthood

(2012) Maitreyi Mazumdar et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Rapid turnover of DNA methylation in human cells

(2012) Yoshiaki Yamagata et al.   Epigenetics

DNA methylation changes in whole blood is associated with exposure to the environmental contaminants, mercury, lead, cadmium and bisphenol A, in women undergoing ovarian stimulation for IVF

(2012) Courtney W. Hanna et al.   HUMAN REPRODUCTION

Panel Advises Tougher Limits on Lead Exposure

(2012) Bridget M. Kuehn   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Lead neurotoxicity: effects on brain nitric oxide synthase

(2012) Concepción Nava-Ruiz et al.   JOURNAL OF MOLECULAR HISTOLOGY

Genome-wide expression and methylation profiling in the aged rodent brain due to early-life Pb exposure and its relevance to aging

(2012) Remi Dosunmu et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Neural differentiation of mouse embryonic stem cells as a tool to assess developmental neurotoxicity in vitro

(2012) Anke Visan et al.   NEUROTOXICOLOGY

Pαx6 Expression in Postmitotic Neurons Mediates the Growth of Axons in Response to SFRP1

(2012) Alvaro Sebastián-Serrano et al.   PLoS One

Influence of developmental lead exposure on expression of DNA methyltransferases and methyl cytosine-binding proteins in hippocampus

(2012) J.S. Schneider et al.   TOXICOLOGY LETTERS

Complete pipeline for Infinium® Human Methylation 450K BeadChip data processing using subset quantile normalization for accurate DNA methylation estimation

(2012) Nizar Touleimat et al.   Epigenomics

Epigenetics of early-life lead exposure and effects on brain development

(2012) Marie-Claude Senut et al.   Epigenomics

Proliferation potential of human amniotic fluid stem cells differently responds to mercury and lead exposure

(2011) C. Gundacker et al.   AMINO ACIDS

Present state and future perspectives of using pluripotent stem cells in toxicology research

(2011) Anna M. Wobus et al.   ARCHIVES OF TOXICOLOGY

Chromatin states in pluripotent, differentiated, and reprogrammed cells

(2011) Cynthia L Fisher et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome

(2011) Juan Sandoval et al.   Epigenetics

Functional Relevance of CpG Island Length for Regulation of Gene Expression

(2011) N. Elango et al.   GENETICS

Embryotoxicity of Lead (II) Acetate and Aroclor 1254 Using a New End Point of the Embryonic Stem Cell Test

(2011) Dae Hyun Baek et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Is lead exposure in early life an environmental risk factor for Schizophrenia? Neurobiological connections and testable hypotheses

(2011) Tomás R. Guilarte et al.   NEUROTOXICOLOGY

Epigenetic mechanisms in memory and synaptic function

(2011) Faraz A Sultan et al.   Epigenomics

Evaluation of the Infinium Methylation 450K technology

(2011) Sarah Dedeurwaerder et al.   Epigenomics

Coordinated waves of gene expression during neuronal differentiation of embryonic stem cells as basis for novel approaches to developmental neurotoxicity testing

(2010) B Zimmer et al.   CELL DEATH AND DIFFERENTIATION

p16promoter methylation in Pb2+-exposed individuals

(2010) Leda Kovatsi et al.   CLINICAL TOXICOLOGY

Biomarkers of Lead Exposure and DNA Methylation within Retrotransposons

(2010) Robert O. Wright et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Semi-automated Sholl analysis for quantifying changes in growth and differentiation of neurons and glia

(2010) John C. Gensel et al.   JOURNAL OF NEUROSCIENCE METHODS

Molecular Neurobiology of Lead (Pb2+): Effects on Synaptic Function

(2010) April P. Neal et al.   MOLECULAR NEUROBIOLOGY

Lead Dysregulates Serine/Threonine Protein Phosphatases in Human Neurons

(2010) Abdur Rahman et al.   NEUROCHEMICAL RESEARCH

Calcium preconditioning triggers neuroprotection in retinal ganglion cells

(2010) S.K. Brandt et al.   NEUROSCIENCE

Low concentrations of nitric oxide delay the differentiation of embryonic stem cells and promote their survival

(2010) J R Tejedo et al.   Cell Death & Disease

Low-Level Lead Exposure and Contingency-Based Responding in Preschoolers: An Exploratory Study

(2009) Melanie McDiarmid Nelson et al.   DEVELOPMENTAL NEUROPSYCHOLOGY

Influence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA

(2009) J. Richard Pilsner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Increased cellular turnover in response to fluoxetine in neuronal precursors derived from human embryonic stem cells

(2009) Eun-Ah Chang et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Altered myelination and axonal integrity in adults with childhood lead exposure: A diffusion tensor imaging study

(2009) Christopher J. Brubaker et al.   NEUROTOXICOLOGY

Human-Induced Pluripotent Stem Cells Produced Under Xeno-Free Conditions

(2009) Pablo Juan Ross et al.   STEM CELLS AND DEVELOPMENT

Standardization of real-time PCR gene expression data from independent biological replicates

(2008) Erik Willems et al.   ANALYTICAL BIOCHEMISTRY

Plexin-A3 and plexin-A4 restrict the migration of sympathetic neurons but not their neural crest precursors

(2008) Kathryn E. Waimey et al.   DEVELOPMENTAL BIOLOGY

Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD

(2008) J. Wu et al.   JOURNAL OF NEUROSCIENCE

Long-Term Functional and Protective Actions of Preconditioning With Hypoxia, Cobalt Chloride, and Desferrioxamine Against Hypoxic-Ischemic Injury in Neonatal Rats

(2008) Nicole M Jones et al.   PEDIATRIC RESEARCH

Ephrins as negative regulators of adult neurogenesis in diverse regions of the central nervous system

(2008) J.-w. Jiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Pax6 Transcription Factor Contributes to both Embryonic and Adult Neurogenesis as a Multifunctional Regulator

(2008) Noriko Osumi et al.   STEM CELLS

Effect of lead on proliferation and neural differentiation of mouse bone marrow-mesenchymal stem cells

(2008) Shabnam Kermani et al.   TOXICOLOGY IN VITRO

Decreased Brain Volume in Adults with Childhood Lead Exposure

(2008) Kim M Cecil et al.   PLOS MEDICINE

Association of Prenatal and Childhood Blood Lead Concentrations with Criminal Arrests in Early Adulthood

(2008) John Paul Wright et al.   PLOS MEDICINE