Epigenetic mechanisms in memory and synaptic function

Promoter Methylation Analysis of SIRT3, SMARCA5, HTERT and CDH1 Genes in Aging and Alzheimer's Disease

(2017) Patrícia Natália Oliveira Silva et al.   JOURNAL OF ALZHEIMERS DISEASE

Folic Acid Potentiates the Effect of Memantine on Spatial Learning and Neuronal Protection in an Alzheimer's Disease Transgenic Model

(2017) Ta-Fu Chen et al.   JOURNAL OF ALZHEIMERS DISEASE

Tissue-specific dysregulation of DNA methylation in aging

(2010) Reid F. Thompson et al.   AGING CELL

Histone deacetylases govern cellular mechanisms underlying behavioral and synaptic plasticity in the developing and adult brain

(2010) Michael J. Morris et al.   BEHAVIOURAL PHARMACOLOGY

Tuning acetylation levels with HAT activators: Therapeutic strategy in neurodegenerative diseases

(2010) B. Ruthrotha Selvi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Dynamic Interplay between Histone H3 Modifications and Protein Interpreters: Emerging Evidence for a “Histone Language”

(2010) Samuel S. Oliver et al.   CHEMBIOCHEM

Joining the dots: from chromatin remodeling to neuronal plasticity

(2010) Loredana Zocchi et al.   CURRENT OPINION IN NEUROBIOLOGY

Histone deacetylases as targets for the treatment of human neurodegenerative diseases

(2010) S.R. D'Mello   DRUG NEWS & PERSPECTIVES

Depolarization induces downregulation of DNMT1 and DNMT3 in primary cortical cultures

(2010) Rajiv P. Sharma et al.   Epigenetics

Epigenetic mechanisms in the dentate gyrus act as a molecular switch in hippocampus-associated memory formation

(2010) Johannes M.H.M. Reul et al.   Epigenetics

Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivation

(2010) Davide Silingardi et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Differential Histone Deacetylase mRNA Expression Patterns in Amyotrophic Lateral Sclerosis

(2010) Claas Janssen et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Histone H1 Poly[ADP]-Ribosylation Regulates the Chromatin Alterations Required for Learning Consolidation

(2010) A. Fontan-Lozano et al.   JOURNAL OF NEUROSCIENCE

Membrane-Associated Glucocorticoid Activity Is Necessary for Modulation of Long-Term Memory via Chromatin Modification

(2010) B. Roozendaal et al.   JOURNAL OF NEUROSCIENCE

CREB Binding Protein Is Required for Both Short-Term and Long-Term Memory Formation

(2010) G. Chen et al.   JOURNAL OF NEUROSCIENCE

Histone Methylation Regulates Memory Formation

(2010) S. Gupta et al.   JOURNAL OF NEUROSCIENCE

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

Widespread transcription at neuronal activity-regulated enhancers

(2010) Tae-Kyung Kim et al.   NATURE

Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathways

(2010) Antonella Riccio   NATURE NEUROSCIENCE

Cortical DNA methylation maintains remote memory

(2010) Courtney A Miller et al.   NATURE NEUROSCIENCE

Epigenetic regulation of the neural transcriptome: the meaning of the marks

(2010) Michael J Meaney et al.   NATURE NEUROSCIENCE

DNA methylation and memory formation

(2010) Jeremy J Day et al.   NATURE NEUROSCIENCE

Epigenetic choreographers of neurogenesis in the adult mammalian brain

(2010) Dengke K Ma et al.   NATURE NEUROSCIENCE

MeCP2 controls BDNF expression and cocaine intake through homeostatic interactions with microRNA-212

(2010) Heh-In Im et al.   NATURE NEUROSCIENCE

Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens

(2010) Quincey LaPlant et al.   NATURE NEUROSCIENCE

Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

(2010) Jian Feng et al.   NATURE NEUROSCIENCE

Active DNA demethylation: many roads lead to Rome

(2010) Susan C. Wu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?

(2010) Wei Deng et al.   NATURE REVIEWS NEUROSCIENCE

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

(2010) Dieter Edbauer et al.   NEURON

CpG Methylation in Neurons: Message, Memory, or Mask?

(2010) Rajiv P Sharma et al.   NEUROPSYCHOPHARMACOLOGY

DNA Methylation Regulates Cocaine-Induced Behavioral Sensitization in Mice

(2010) Kaili Anier et al.   NEUROPSYCHOPHARMACOLOGY

Nuclear protein phosphatase-1: an epigenetic regulator of fear memory and amygdala long-term potentiation

(2010) K. Koshibu et al.   NEUROSCIENCE

Alteration of working memory but not in anxiety or stress response in p300/CBP associated factor (PCAF) histone acetylase knockout mice bred on a C57BL/6 background

(2010) Florian Duclot et al.   NEUROSCIENCE LETTERS

Genome-wide assessment of differential roles for p300 and CBP in transcription regulation

(2010) Y. F. M. Ramos et al.   NUCLEIC ACIDS RESEARCH

The Site Specific Demethylation in the 5′-Regulatory Area of NMDA Receptor 2B Subunit Gene Associated with CIE-Induced Up-Regulation of Transcription

(2010) Mei Qiang et al.   PLoS One

Analysis of proteome dynamics in the mouse brain

(2010) J. C. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endogenous siRNAs and noncoding RNA-derived small RNAs are expressed in adult mouse hippocampus and are up-regulated in olfactory discrimination training

(2010) N. R. Smalheiser et al.   RNA

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Essential Role of the Histone Methyltransferase G9a in Cocaine-Induced Plasticity

(2010) I. Maze et al.   SCIENCE

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Histone H3 Acetylation is Asymmetrically Induced Upon Learning in Identified Neurons of the Food Aversion Network in the Mollusk Helix Lucorum

(2010) Alexandra B. Danilova et al.   Frontiers in Behavioral Neuroscience

Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene

(2009) Tania L. Roth et al.   BIOLOGICAL PSYCHIATRY

Histone Deacetylase Inhibitors and Neurodegenerative Disorders: Holding the Promise

(2009) Antonello Mai et al.   CURRENT PHARMACEUTICAL DESIGN

Epigenetic dysregulation in cognitive disorders

(2009) Johannes Gräff et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

An operational definition of epigenetics

(2009) S. L. Berger et al.   GENES & DEVELOPMENT

Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation ofBdnfgene promoter 1

(2009) Feng Tian et al.   JOURNAL OF NEUROCHEMISTRY

PolyADP-ribosylation is required for long-term memory formation in mammals

(2009) Shmuel Goldberg et al.   JOURNAL OF NEUROCHEMISTRY

Protein Phosphatase 1 Regulates the Histone Code for Long-Term Memory

(2009) K. Koshibu et al.   JOURNAL OF NEUROSCIENCE

Histone Deacetylases 1 and 2 Form a Developmental Switch That Controls Excitatory Synapse Maturation and Function

(2009) M. W. Akhtar et al.   JOURNAL OF NEUROSCIENCE

Histone acetylation is recruited in consolidation as a molecular feature of stronger memories

(2009) N. Federman et al.   LEARNING & MEMORY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Appetitive Pavlovian conditioned stimuli increase CREB phosphorylation in the nucleus accumbens

(2009) Michael W. Shiflett et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Characterization of Small RNAs in Aplysia Reveals a Role for miR-124 in Constraining Synaptic Plasticity through CREB

(2009) Priyamvada Rajasethupathy et al.   NEURON

Genome-wide Analysis of Chromatin Regulation by Cocaine Reveals a Role for Sirtuins

(2009) William Renthal et al.   NEURON

Control of Cognition and Adaptive Behavior by the GLP/G9a Epigenetic Suppressor Complex

(2009) Anne Schaefer et al.   NEURON

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

Chronic Cocaine-Induced H3 Acetylation and Transcriptional Activation of CaMKIIα in the Nucleus Accumbens Is Critical for Motivation for Drug Reinforcement

(2009) Lei Wang et al.   NEUROPSYCHOPHARMACOLOGY

Selective Boosting of Transcriptional and Behavioral Responses to Drugs of Abuse by Histone Deacetylase Inhibition

(2009) Carles Sanchis-Segura et al.   NEUROPSYCHOPHARMACOLOGY

Transcription Factors in Long-Term Memory and Synaptic Plasticity

(2009) Cristina M. Alberini   PHYSIOLOGICAL REVIEWS

Modulation of long-term memory for object recognition via HDAC inhibition

(2009) D. P. Stefanko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuronal Activity-Induced Gadd45b Promotes Epigenetic DNA Demethylation and Adult Neurogenesis

(2009) D. K. Ma et al.   SCIENCE

Multiple roles of HDAC inhibition in neurodegenerative conditions

(2009) De-Maw Chuang et al.   TRENDS IN NEUROSCIENCES

Epigenetic codes in cognition and behaviour

(2008) Johannes Gräff et al.   BEHAVIOURAL BRAIN RESEARCH

Activity-dependent NR2B expression is mediated by MeCP2-dependent epigenetic regulation

(2008) Sangwoo Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of reelin in adult synaptic function and the genetic and epigenetic regulation of the reelin gene

(2008) Jonathan M. Levenson et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Rett Syndrome and the Impact of MeCP2 Associated Transcriptional Mechanisms on Neurotransmission

(2008) Lisa M. Monteggia et al.   BIOLOGICAL PSYCHIATRY

DNA Demethylation in Zebrafish Involves the Coupling of a Deaminase, a Glycosylase, and Gadd45

(2008) Kunal Rai et al.   CELL

Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation

(2008) Ali Shilatifard   CURRENT OPINION IN CELL BIOLOGY

Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development

(2008) Jessica L. MacDonald et al.   DEVELOPMENTAL DYNAMICS

The forced swimming-induced behavioural immobility response involves histone H3 phospho-acetylation and c-Fos induction in dentate gyrus granule neurons via activation of theN-methyl-d-aspartate/extracellular signal-regulated kinase/mitogen- and stress-activated kinase signalling pathway

(2008) Yalini Chandramohan et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Single immobilization stress differentially alters the expression profile of transcripts of the brain-derived neurotrophic factor ( BDNF) gene and histone acetylation at its promoters in the rat hippocampus

(2008) Manabu Fuchikami et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Cue-Elicited Reward-Seeking Requires Extracellular Signal-Regulated Kinase Activation in the Nucleus Accumbens

(2008) M. W. Shiflett et al.   JOURNAL OF NEUROSCIENCE

Epigenetic Regulation of bdnf Gene Transcription in the Consolidation of Fear Memory

(2008) F. D. Lubin et al.   JOURNAL OF NEUROSCIENCE

Activity-Dependent Suppression of Miniature Neurotransmission through the Regulation of DNA Methylation

(2008) E. D. Nelson et al.   JOURNAL OF NEUROSCIENCE

Epigenetics in the Nervous System

(2008) Y. Jiang et al.   JOURNAL OF NEUROSCIENCE

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice

(2008) Andrea Fuso et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Transient cyclical methylation of promoter DNA

(2008) Sara Kangaspeska et al.   NATURE

A phosphatase cascade by which rewarding stimuli control nucleosomal response

(2008) Alexandre Stipanovich et al.   NATURE

Control of the establishment of aversive memory by calcineurin and Zif268

(2008) Karsten Baumgärtel et al.   NATURE NEUROSCIENCE

Epigenetic changes in Alzheimer's disease: Decrements in DNA methylation

(2008) Diego Mastroeni et al.   NEUROBIOLOGY OF AGING

Effect of 5-Azacytidine on the Methylation Aspects of NMDA Receptor NR2B Gene in the Cultured Cortical Neurons of Mice

(2008) C. R. Marutha Ravindran et al.   NEUROCHEMICAL RESEARCH

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

(2008) Sun-Chong Wang et al.   PLoS One

MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription

(2008) M. Chahrour et al.   SCIENCE

DNA methylation and histone acetylation work in concert to regulate memory formation and synaptic plasticity

(2007) Courtney A. Miller et al.   NEUROBIOLOGY OF LEARNING AND MEMORY