Predicting Skin Sensitizer Potency Based on In Vitro Data from KeratinoSens and Kinetic Peptide Binding: Global Versus Domain-Based Assessment

Integrating non-animal test information into an adaptive testing strategy – skin sensitization proof of concept case

(2014) Joanna Jaworska   ALTEX-Alternatives to Animal Experimentation

An epidermal equivalent assay for identification and ranking potency of contact sensitizers

(2013) Susan Gibbs et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Analogues of the Epoxy Resin Monomer Diglycidyl Ether of Bisphenol F: Effects on Contact Allergenic Potency and Cytotoxicity

(2012) Niamh M. O'Boyle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Chemical Reactivity and Skin Sensitization Potential for Benzaldehydes: Can Schiff Base Formation Explain Everything?

(2012) Andreas Natsch et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Allergic contact dermatitis: xenoinflammation of the skin

(2012) Stefan F Martin   CURRENT OPINION IN IMMUNOLOGY

Prediction of skin sensitization potency of chemicals by human Cell Line Activation Test (h-CLAT) and an attempt at classifying skin sensitization potency

(2012) Yuko Nukada et al.   TOXICOLOGY IN VITRO

A genomic biomarker signature can predict skin sensitizers using a cell-based in vitro alternative to animal tests

(2011) Henrik Johansson et al.   BMC GENOMICS

Relating Skin Sensitizing Potency to Chemical Reactivity: Reactive Michael Acceptors Inhibit NF-κB Signaling and Are Less Sensitizing than SNAr- and SN2- Reactive Chemicals

(2011) Andreas Natsch et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Structure–Activity Relationship between the in Vivo Skin Sensitizing Potency of Analogues of Phenyl Glycidyl Ether and the Induction of Nrf2-Dependent Luciferase Activity in the KeratinoSens in Vitro Assay

(2011) Tamara Delaine et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Predictive performance for human skin sensitizing potential of the human cell line activation test (h-CLAT)

(2011) Yuko Nukada et al.   CONTACT DERMATITIS

Evaluating the sensitization potential of surfactants: Integrating data from the local lymph node assay, guinea pig maximization test, and in vitro methods in a weight-of-evidence approach

(2011) Nicholas Ball et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Non-animal sensitization testing: State-of-the-art

(2010) Rob J. Vandebriel et al.   CRITICAL REVIEWS IN TOXICOLOGY

Assessment of Chemical Skin-Sensitizing Potency by an In Vitro Assay Based on Human Dendritic Cells

(2010) Nathalie Lambrechts et al.   TOXICOLOGICAL SCIENCES

Chemical Allergy: Translating Biology into Hazard Characterization

(2010) I. Kimber et al.   TOXICOLOGICAL SCIENCES

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

(2010) Roger Emter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The intra- and inter-laboratory reproducibility and predictivity of the KeratinoSens assay to predict skin sensitizers in vitro: Results of a ring-study in five laboratories

(2010) Natsch Andreas et al.   TOXICOLOGY IN VITRO

Reduced Sensitizing Capacity of Epoxy Resin Systems: A Structure−Activity Relationship Study

(2009) Ida B. Niklasson et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Nuclear Magnetic Resonance Studies on Covalent Modification of Amino Acids Thiol and Amino Residues by Monofunctional Aryl13C-Isocyanates, Models of Skin and Respiratory Sensitizers: Transformation of Thiocarbamates into Urea Adducts

(2009) Olivier Fleischel et al.   CHEMICAL RESEARCH IN TOXICOLOGY

High Throughput Kinetic Profiling Approach for Covalent Binding to Peptides: Application to Skin Sensitization Potency of Michael Acceptor Electrophiles

(2009) David W. Roberts et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Filling the Concept with Data: Integrating Data from Different In Vitro and In Silico Assays on Skin Sensitizers to Explore the Battery Approach for Animal-Free Skin Sensitization Testing

(2008) Andreas Natsch et al.   TOXICOLOGICAL SCIENCES

LC-MS–Based Characterization of the Peptide Reactivity of Chemicals to Improve the In Vitro Prediction of the Skin Sensitization Potential

(2008) Andreas Natsch et al.   TOXICOLOGICAL SCIENCES