Cross Talk between Keratinocytes and Dendritic Cells: Impact on the Prediction of Sensitization

Integration of Langerhans-like cells into a human skin equivalent

(2010) Vesselina Laubach et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

A newin vitromethod for identifying chemical sensitizers combining peptide binding with ARE/EpRE-mediated gene expression in human skin cells

(2010) James M. McKim et al.   Cutaneous and Ocular Toxicology

Keratinocyte Gene Expression Profiles Discriminate Sensitizing and Irritating Compounds

(2010) Rob J. Vandebriel et al.   TOXICOLOGICAL SCIENCES

Use of the human monocytic leukemia THP-1 cell line and co-incubation with microsomes to identify and differentiate hapten and prohapten sensitizers

(2010) Itai Chipinda et al.   TOXICOLOGY

Performance of a novel keratinocyte-based reporter cell line to screen skin sensitizers in vitro

(2010) Roger Emter et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Identifying and characterizing chemical skin sensitizers without animal testing: Colipa’s research and method development program

(2010) P. Aeby et al.   TOXICOLOGY IN VITRO

Predicting skin sensitization potential and inter-laboratory reproducibility of a human Cell Line Activation Test (h-CLAT) in the European Cosmetics Association (COLIPA) ring trials

(2010) Hitoshi Sakaguchi et al.   TOXICOLOGY IN VITRO

Effector and regulatory mechanisms in allergic contact dermatitis

(2009) M. Vocanson et al.   ALLERGY

Cutaneous Metabolic Activation of Carvoxime, a Self-Activating, Skin-Sensitizing Prohapten

(2009) Hagen Ott et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TGF-β1 dampens the susceptibility of dendritic cells to environmental stimulation, leading to the requirement for danger signals for activation

(2009) Tomoyuki Ohtani et al.   IMMUNOLOGY

Updating the skin sensitizationin vitrodata assessment paradigm in 2009

(2009) David A. Basketter et al.   JOURNAL OF APPLIED TOXICOLOGY

The Cutaneous Biochemical Redox Barrier: A Component of the Innate Immune Defenses against Sensitization by Highly Reactive Environmental Xenobiotics

(2009) C. Pickard et al.   JOURNAL OF IMMUNOLOGY

Keratinocytes Function as Accessory Cells for Presentation of Endogenous Antigen Expressed in the Epidermis

(2009) Brian S. Kim et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Investigation of Peptide Reactivity of Pro-hapten Skin Sensitizers Using a Peroxidase-Peroxide Oxidation System

(2009) G. Frank Gerberick et al.   TOXICOLOGICAL SCIENCES

Comparative DNA microarray analysis of human monocyte derived dendritic cells and MUTZ-3 cells exposed to the moderate skin sensitizer cinnamaldehyde

(2009) François Python et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound

(2009) G. Galvão dos Santos et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers

(2009) Jutta Bonifas et al.   TOXICOLOGY IN VITRO

The relationship between CD86/CD54 expression and THP-1 cell viability in an in vitro skin sensitization test – human cell line activation test (h-CLAT)

(2008) Hitoshi Sakaguchi et al.   CELL BIOLOGY AND TOXICOLOGY

Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity

(2008) Stefan F. Martin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

HMOX1 and NQO1 Genes are Upregulated in Response to Contact Sensitizers in Dendritic Cells and THP-1 Cell Line: Role of the Keap1/Nrf2 Pathway

(2008) Nadège Ade et al.   TOXICOLOGICAL SCIENCES

Cytochrome P450-mediated activation of the fragrance compound geraniol forms potent contact allergens

(2008) Lina Hagvall et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY