Network-Based Integration of Disparate Omic Data To Identify "Silent Players" in Cancer

HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant

(2015) Whitfield B. Growdon et al.   GYNECOLOGIC ONCOLOGY

Mutant Cbl proteins as oncogenic drivers in myeloproliferative disorders

(2015) Mayumi Naramura et al.   Oncotarget

Targeting MCT-1 oncogene inhibits Shc pathway and xenograft tumorigenicity

(2015) Hung-Ju Shih et al.   Oncotarget

Ras Promotes Transforming Growth Factor-β (TGF-β)-induced Epithelial-Mesenchymal Transition via a Leukotriene B4Receptor-2-linked Cascade in Mammary Epithelial Cells

(2014) Hyunju Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A human immunodeficiency caused by mutations in the PIK3R1 gene

(2014) Marie-Céline Deau et al.   JOURNAL OF CLINICAL INVESTIGATION

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation

(2014) F De Falco et al.   LEUKEMIA

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

The p85 Regulatory Subunit of PI3K Mediates cAMP-PKA and Insulin Biological Effects on MCF-7 Cell Growth and Motility

(2014) E. Di Zazzo et al.   TheScientificWorldJOURNAL

Activation of the NOTCH Pathway in Head and Neck Cancer

(2013) W. Sun et al.   CANCER RESEARCH

Involvement of Lyn and the Atypical Kinase SgK269/PEAK1 in a Basal Breast Cancer Signaling Pathway

(2013) D. R. Croucher et al.   CANCER RESEARCH

Network-Based Interpretation of Genomic Variation Data

(2013) Bjarni V. Halldórsson et al.   JOURNAL OF MOLECULAR BIOLOGY

Altered glucose metabolism in Harvey-rastransformed MCF10A cells

(2013) Wei Zheng et al.   MOLECULAR CARCINOGENESIS

Network-based stratification of tumor mutations

(2013) Matan Hofree et al.   NATURE METHODS

Network Signatures of Survival in Glioblastoma Multiforme

(2013) Vishal N. Patel et al.   PLoS Computational Biology

Network-based Survival Analysis Reveals Subnetwork Signatures for Predicting Outcomes of Ovarian Cancer Treatment

(2013) Wei Zhang et al.   PLoS Computational Biology

Signalling through the grapevine

(2012) Ivan Dikic et al.   EMBO REPORTS

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

HIPPIE: Integrating Protein Interaction Networks with Experiment Based Quality Scores

(2012) Martin H. Schaefer et al.   PLoS One

Cancer risk in patients with Noonan syndrome carrying a PTPN11 mutation

(2011) Marjolijn C J Jongmans et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Mutual exclusivity analysis identifies oncogenic network modules

(2011) G. Ciriello et al.   GENOME RESEARCH

NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL

(2011) I. Del Giudice et al.   HAEMATOLOGICA

Vavien: An Algorithm for Prioritizing Candidate Disease Genes Based on Topological Similarity of Proteins in Interaction Networks

(2011) Sinan Erten et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Algorithms for Detecting Significantly Mutated Pathways in Cancer

(2011) Fabio Vandin et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

(2010) S. A. Forbes et al.   NUCLEIC ACIDS RESEARCH

An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer

(2010) Rod K. Nibbe et al.   PLoS Computational Biology

Associating Genes and Protein Complexes with Disease via Network Propagation

(2010) Oron Vanunu et al.   PLoS Computational Biology

The NCBI BioSystems database

(2009) Lewis Y. Geer et al.   NUCLEIC ACIDS RESEARCH

Phosphoproteomics: Unraveling the Signaling Web

(2008) Paul H. Huang et al.   MOLECULAR CELL