Interpreting Stress Responses during Routine Toxicity Studies

Glucocorticoids, master modulators of the thymic catecholaminergic system?

(2017) I. Pilipović et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Congenital absence of vasopressin and age-dependent changes in ACTH and corticosterone stress responses in rats

(2016) D. Zelena et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Interleukin-1 (IL-1) in stress-induced activation of limbic-hypothalamic-pituitary adrenal axis

(2014) Anna Gądek-Michalska et al.   Pharmacological Reports

Acute Stress Differently Modulates Beta 1, Beta 2 and Beta 3 Adrenoceptors in T Cells, but Not in B Cells, from the Rat Spleen

(2012) Marcela Laukova et al.   NEUROIMMUNOMODULATION

Effects of stress across the lifespan

(2012) James I. Koenig et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Assessment of Circulating Hormones in Regulatory Toxicity Studies II. Male Reproductive Hormones

(2012) Robert E. Chapin et al.   TOXICOLOGIC PATHOLOGY

PACAP: a master regulator of neuroendocrine stress circuits and the cellular stress response

(2011) Nikolas Stroth et al.   Annals of the New York Academy of Sciences

Early-life stress mediated modulation of adult neurogenesis and behavior

(2011) A. Korosi et al.   BEHAVIOURAL BRAIN RESEARCH

Diagnosis and management of anaemia of chronic disease: current status

(2011) Jonathan O. Cullis   BRITISH JOURNAL OF HAEMATOLOGY

PACAP is Implicated in the Stress Axes

(2011) Hitoshi Hashimoto et al.   CURRENT PHARMACEUTICAL DESIGN

Sympathetic and parasympathetic responses to social stress across adolescence

(2011) Tom Hollenstein et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Depression, stress, epilepsy and adult neurogenesis

(2011) Steve C. Danzer   EXPERIMENTAL NEUROLOGY

Annual Research Review: Prenatal stress and the origins of psychopathology: an evolutionary perspective

(2011) Vivette Glover   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

Sex Steroids and the Control of the Kiss1 System: Developmental Roles and Major Regulatory Actions

(2011) D. García-Galiano et al.   JOURNAL OF NEUROENDOCRINOLOGY

Vulnerability to Depression: From Brain Neuroplasticity to Identification of Biomarkers

(2011) A. Blugeot et al.   JOURNAL OF NEUROSCIENCE

Stress Acts Cumulatively To Precipitate Alzheimer's Disease-Like Tau Pathology and Cognitive Deficits

(2011) I. Sotiropoulos et al.   JOURNAL OF NEUROSCIENCE

White-Coat Effect on Systemic Blood Pressure in Retired Racing Greyhounds

(2011) C.L. Marino et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

The effects of enriching laboratory cages using various physical structures on multiple measures of welfare in singly-housed rats

(2011) Usama A Abou-Ismail et al.   LABORATORY ANIMALS

Stress revisited: A critical evaluation of the stress concept

(2011) J.M. Koolhaas et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Evidence for a lack of phasic inhibitory properties of habituated stressors on HPA axis responses in rats

(2011) C.V. Masini et al.   PHYSIOLOGY & BEHAVIOR

Social Isolation-Induced Aggression Potentiates Anxiety and Depressive-Like Behavior in Male Mice Subjected to Unpredictable Chronic Mild Stress

(2011) Xian-cang Ma et al.   PLoS One

The Importance of Reporting Housing and Husbandry in Rat Research

(2011) Eric M. Prager et al.   Frontiers in Behavioral Neuroscience

Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society

(2011) D.J. Leishman et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Lifetime Consequences of Combined Maternal Lead and Stress

(2010) Deborah A. Cory-Slechta et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Pathologic role of stressed-induced glucocorticoids in drug-induced liver injury in mice

(2010) Mary Jane Masson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Depression gets old fast: do stress and depression accelerate cell aging?

(2010) Owen M. Wolkowitz et al.   DEPRESSION AND ANXIETY

Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis

(2010) Yongwen Chen et al.   FASEB JOURNAL

Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer’s disease-linked APPswe/PS1ΔE9 mice

(2010) Yuan-Shih Hu et al.   FASEB JOURNAL

Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons

(2010) A.M. Magariños et al.   HIPPOCAMPUS

Adrenocortical hypertrophy: establishing cause and toxicological significance

(2010) Philip W. Harvey et al.   JOURNAL OF APPLIED TOXICOLOGY

Environmental enrichment requires adult neurogenesis to facilitate the recovery from psychosocial stress

(2010) R J Schloesser et al.   MOLECULAR PSYCHIATRY

Early life influences on emotional reactivity: Evidence that social enrichment has greater effects than handling on anxiety-like behaviors, neuroendocrine responses to stress and central BDNF levels

(2010) Francesca Cirulli et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Chronic stress impairs learning and hippocampal cell proliferation in senescence-accelerated prone mice

(2010) Weihong Yan et al.   NEUROSCIENCE LETTERS

Nutritional Determinants of Puberty

(2010) Judy L. Cameron   NUTRITION REVIEWS

Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression

(2010) Cliona M. O'Mahony et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Effects of Enriched Physical and Social Environments on Motor Performance, Associative Learning, and Hippocampal Neurogenesis in Mice

(2010) Noelia Madroñal et al.   PLoS One

Short-Term Environmental Enrichment Enhances Adult Neurogenesis, Vascular Network and Dendritic Complexity in the Hippocampus of Type 1 Diabetic Mice

(2010) Juan Beauquis et al.   PLoS One

Stress coping stimulates hippocampal neurogenesis in adult monkeys

(2010) D. M. Lyons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methylmercury induced toxicogenomic response in C57 and SWV mouse embryos undergoing neural tube closure

(2010) Joshua F. Robinson et al.   REPRODUCTIVE TOXICOLOGY

Notch regulation of early thymocyte development

(2010) Yumi Yashiro-Ohtani et al.   SEMINARS IN IMMUNOLOGY

Sex differences in hypothalamic–pituitary–adrenal axis function in patients with chronic pain syndrome

(2010) Julie M. Turner-Cobb et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Enhanced Learning Deficits in Female Rats Following Lifetime Pb Exposure Combined with Prenatal Stress

(2010) Deborah A. Cory-Slechta et al.   TOXICOLOGICAL SCIENCES

Diurnal rhythm and stress regulate dendritic architecture and spine density of pyramidal neurons in the rat infralimbic cortex

(2009) Claudia Perez-Cruz et al.   BEHAVIOURAL BRAIN RESEARCH

Chronic stress in adulthood followed by intermittent stress impairs spatial memory and the survival of newborn hippocampal cells in aging animals: prevention by FGL, a peptide mimetic of neural cell adhesion molecule

(2009) Érika Borcel et al.   BEHAVIOURAL PHARMACOLOGY

Sensing pathogens and danger signals by the inflammasome

(2009) Joao HF Pedra et al.   CURRENT OPINION IN IMMUNOLOGY

Dysregulation of T-Cell Development in Adrenal Glucocorticoid-Deprived Rats

(2009) Zorica Stojić-Vukanić et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The NGF saga: From animal models of psychosocial stress to stress-related psychopathology

(2009) Francesca Cirulli et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The hematology of anorexia nervosa

(2009) Gero Hütter et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Involvement of Oxidative Stress in Increases in the Serum Levels of Various Enzymes and Components in Rats with Water-Immersion Restraint Stress

(2009) Yoshiji Ohta et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Behavioural and Neurochemical Consequences of Early Weaning in Rodents

(2009) T. Kikusui et al.   JOURNAL OF NEUROENDOCRINOLOGY

Environmental Enrichment Restores Memory Functioning in Mice with Impaired IL-1 Signaling via Reinstatement of Long-Term Potentiation and Spine Size Enlargement

(2009) I. Goshen et al.   JOURNAL OF NEUROSCIENCE

Enhancing versus Suppressive Effects of Stress on Immune Function: Implications for Immunoprotection and Immunopathology

(2009) Firdaus S. Dhabhar   NEUROIMMUNOMODULATION

Estrogen impairs glucocorticoid dependent negative feedback on the hypothalamic–pituitary–adrenal axis via estrogen receptor alpha within the hypothalamus

(2009) M.J. Weiser et al.   NEUROSCIENCE

Catecholaminergic Systems in Stress: Structural and Molecular Genetic Approaches

(2009) Richard Kvetnansky et al.   PHYSIOLOGICAL REVIEWS

5-HT1A receptor function in major depressive disorder

(2009) Jonathan Savitz et al.   PROGRESS IN NEUROBIOLOGY

Effects of social housing of sexually mature male cynomolgus monkeys during general and reproductive toxicity evaluation

(2009) Marc O. Niehoff et al.   REPRODUCTIVE TOXICOLOGY

Frequency of Different Estrous Stages in Purpose-bred Beagles: A Retrospective Study

(2009) Sundeep A. Chandra et al.   TOXICOLOGIC PATHOLOGY

Physiology and Endocrinology of the Ovarian Cycle in Macaques

(2009) Gerhard F. Weinbauer et al.   TOXICOLOGIC PATHOLOGY

Heart-brain interactions in mental stress-induced myocardial ischemia

(2009) Robert Soufer et al.   Current Cardiology Reports

Expressions of Hippocampal Mineralocorticoid Receptor (MR) and Glucocorticoid Receptor (GR) in the Single-Prolonged Stress-Rats

(2008) Du Zhe et al.   ACTA HISTOCHEMICA ET CYTOCHEMICA

Catecholamines as immunomodulators: A role for adrenoceptor-mediated mechanisms in fine tuning of T-cell development

(2008) Gordana Leposavić et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Enhanced cell death in hippocampus and emergence of cognitive impairments following a localized mini-stroke in hippocampus if preceded by a previous episode of acute stress

(2008) Robert J. McDonald et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state

(2008) Heather N. Richardson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Central effects of stress hormones in health and disease: Understanding the protective and damaging effects of stress and stress mediators

(2008) Bruce S. McEwen   EUROPEAN JOURNAL OF PHARMACOLOGY

Interleukin-1 (IL-1): A central regulator of stress responses

(2008) Inbal Goshen et al.   FRONTIERS IN NEUROENDOCRINOLOGY

The role of kisspeptin in the control of gonadotrophin secretion

(2008) A.K. Roseweir et al.   HUMAN REPRODUCTION UPDATE

Voluntary wheel running initially increases adrenal sensitivity to adrenocorticotrophic hormone, which is attenuated with long-term training

(2008) Jonathan E. Campbell et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cytokines, leptin, and stress-induced thymic atrophy

(2008) Amanda L. Gruver et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immune Dysregulation and Chronic Stress among Older Adults: A Review

(2008) Jean-Philippe Gouin et al.   NEUROIMMUNOMODULATION

Persistent depressive state after chronic stress in rats is accompanied by HPA axis dysregulation and reduced prefrontal dopaminergic neurotransmission

(2008) K MIZOGUCHI et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Prenatal Restraint Stress Generates Two Distinct Behavioral and Neurochemical Profiles in Male and Female Rats

(2008) Anna Rita Zuena et al.   PLoS One

Natural glucocorticoids induce expansion of all developmental stages of murine bone marrow granulocytes without inhibiting function

(2008) M. D. Trottier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic psychosocial factors and acute physiological responses to laboratory-induced stress in healthy populations: A quantitative review of 30 years of investigations.

(2008) Yoichi Chida et al.   PSYCHOLOGICAL BULLETIN

Characterization of Age- and Gender-related Changes in the Spleen and Thymus from Control Cynomolgus Macaques Used in Toxicity Studies

(2008) Melanie S. Spoor et al.   TOXICOLOGIC PATHOLOGY

Effects of Food Restriction on Testis and Accessory Sex Glands in Maturing Rats

(2008) Sabine Rehm et al.   TOXICOLOGIC PATHOLOGY

Stressor-specific alterations in corticosterone and immune responses in mice

(2007) Stephanie L. Bowers et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-18 and stress

(2007) Shuei Sugama et al.   BRAIN RESEARCH REVIEWS

Epigenetic programming of the stress response in male and female rats by prenatal restraint stress

(2007) Muriel Darnaudéry et al.   BRAIN RESEARCH REVIEWS

Prenatal corticosteroid exposure affects hippocampal plasticity and reduces lifespan

(2007) C.W. Noorlander et al.   Developmental Neurobiology