Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose

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Title
Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose
Authors
Keywords
-
Journal
CHEMICAL RESEARCH IN TOXICOLOGY
Volume 21, Issue 9, Pages 1814-1822
Publisher
American Chemical Society (ACS)
Online
2008-08-09
DOI
10.1021/tx800161s

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