Growing Tissues in Real and Simulated Microgravity: New Methods for Tissue Engineering

Microgravity-induced apoptosis in cultured glial cells

(2015) BM Uva et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Calcium influx through stretch-activated channels mediates microfilament reorganization in osteoblasts under simulated weightlessness

(2013) Mingzhi Luo et al.   ADVANCES IN SPACE RESEARCH

Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission

(2013) Jessica Pietsch et al.   BIOMATERIALS

The Impact of Altered Gravity and Vibration on Endothelial Cells During a Parabolic Flight

(2013) Markus Wehland et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Mechanosensitivity and compositional dynamics of cell–matrix adhesions

(2013) Herbert B Schiller et al.   EMBO REPORTS

Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space

(2013) Xiao Ma et al.   FASEB JOURNAL

Interaction of Proteins Identified in Human Thyroid Cells

(2013) Jessica Pietsch et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Disruption of NF-κB1 prevents bone loss caused by mechanical unloading

(2013) Hitomi Nakamura et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Identification of miRNAs involved in long-term simulated microgravity response in Solanum lycopersicum

(2013) Dongqian Xu et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Genomic Approach to Identify Factors That Drive the Formation of Three-Dimensional Structures by EA.hy926 Endothelial Cells

(2013) Xiao Ma et al.   PLoS One

Actin Microfilament Mediates Osteoblast Cbfa1 Responsiveness to BMP2 under Simulated Microgravity

(2013) Zhongquan Dai et al.   PLoS One

Changes in Morphology, Gene Expression and Protein Content in Chondrocytes Cultured on a Random Positioning Machine

(2013) Ganna Aleshcheva et al.   PLoS One

Effects of Gravitational Mechanical Unloading in Endothelial Cells: Association between Caveolins, Inflammation and Adhesion Molecules

(2013) S. Marlene Grenon et al.   Scientific Reports

Observing the Mouse Thyroid Sphingomyelin Under Space Conditions: A Case Study from the MDS Mission in Comparison with Hypergravity Conditions

(2012) E. Albi et al.   ASTROBIOLOGY

Ground-Based Facilities for Simulation of Microgravity: Organism-Specific Recommendations for Their Use, and Recommended Terminology

(2012) Raul Herranz et al.   ASTROBIOLOGY

Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids

(2012) Jirka Grosse et al.   FASEB JOURNAL

Model microgravity enhances endothelium differentiation of mesenchymal stem cells

(2012) Xiaofeng Zhang et al.   NATURWISSENSCHAFTEN

The Impact of Long-Term Exposure to Space Environment on Adult Mammalian Organisms: A Study on Mouse Thyroid and Testis

(2012) Maria Angela Masini et al.   PLoS One

Effects of Simulated Microgravity on Human Umbilical Vein Endothelial Cell Angiogenesis and Role of the PI3K-Akt-eNOS Signal Pathway

(2012) Fei Shi et al.   PLoS One

Loss of Parafollicular Cells during Gravitational Changes (Microgravity, Hypergravity) and the Secret Effect of Pleiotrophin

(2012) Elisabetta Albi et al.   PLoS One

Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces

(2012) Jessica Pietsch et al.   PROTEOMICS

Human mesenchymal stem cells are sensitive to abnormal gravity and exhibit classic apoptotic features

(2011) R. Meng et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Vascular tissue engineering: Towards the next generation vascular grafts

(2011) Yuji Naito et al.   ADVANCED DRUG DELIVERY REVIEWS

Thyrotropin Receptor and Membrane Interactions in FRTL-5 Thyroid Cell Strain in Microgravity

(2011) E. Albi et al.   ASTROBIOLOGY

Tissue engineering of functional articular cartilage: the current status

(2011) Linda Kock et al.   CELL AND TISSUE RESEARCH

Differential Gene Regulation under Altered Gravity Conditions in Follicular Thyroid Cancer Cells: Relationship between the Extracellular Matrix and the Cytoskeleton

(2011) Claudia Ulbrich et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Effects of Weightlessness on the Human Organism and Mammalian Cells

(2011) J. Pietsch et al.   CURRENT MOLECULAR MEDICINE

Impact of simulated microgravity on microvascular endothelial cell apoptosis

(2011) Chun-Yan Kang et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

How and why does the proteome respond to microgravity?

(2011) Daniela Grimm et al.   Expert Review of Proteomics

Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells

(2011) Jirka Grosse et al.   FASEB JOURNAL

A proteomic approach to analysing spheroid formation of two human thyroid cell lines cultured on a random positioning machine

(2011) Jessica Pietsch et al.   PROTEOMICS

Thyroid Cell Growth: Sphingomyelin Metabolism as Non-Invasive Marker for Cell Damage Acquired during Spaceflight

(2010) Elisabetta Albi et al.   ASTROBIOLOGY

Low-Shear Modelled Microgravity Environment Maintains Morphology and Differentiated Functionality of Primary Porcine Hepatocyte Cultures

(2010) Leonard J. Nelson et al.   CELLS TISSUES ORGANS

Characterization of Human Chondrocytes Exposed to Simulated Microgravity

(2010) Claudia Ulbrich et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The expression ofp53-regulated genes in human cultured lymphoblastoid TSCE5 and WTK1 cell lines during spaceflight

(2010) Akihisa Takahashi et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Computational fluid dynamics modeling of momentum transport in rotating wall perfused bioreactor for cartilage tissue engineering

(2010) Mahmut N. Cinbiz et al.   JOURNAL OF BIOTECHNOLOGY

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

Simulated microgravity perturbs actin polymerization to promote nitric oxide-associated migration in human immortalized Eahy926 cells

(2010) Jamila H. Siamwala et al.   PROTOPLASMA

Neocartilage Formation in 1 g, Simulated, and Microgravity Environments: Implications for Tissue Engineering

(2010) Vlada Stamenković et al.   TISSUE ENGINEERING PART A

Simulated Microgravity Affects Growth of Escherichia coli and Recombinant β-d-Glucuronidase Production

(2009) Liang Xiang et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Establishment of Three-Dimensional Tissue-engineered Bone Constructs Under Microgravity-simulated Conditions

(2009) Fang Jin et al.   ARTIFICIAL ORGANS

Cultivation of lacrimal gland acinar cells in a microgravity environment

(2009) S Schrader et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Blockade of Neoangiogenesis, a New and Promising Technique to Control the Growth of Malignant Tumors and their Metastases

(2009) Daniela Grimm et al.   Current Vascular Pharmacology

Excellent effect of three-dimensional culture condition on pancreatic islets

(2009) Yan Hou et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Clinorotation upregulates inducible nitric oxide synthase by inhibiting AP-1 activation in human umbilical vein endothelial cells

(2009) Yong-Chun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Technology and Developments for the Random Positioning Machine, RPM

(2009) A. G. Borst et al.   MICROGRAVITY SCIENCE AND TECHNOLOGY

Detrimental Effects of Microgravity on Mouse Preimplantation Development In Vitro

(2009) Sayaka Wakayama et al.   PLoS One

Stretching Single Talin Rod Molecules Activates Vinculin Binding

(2009) A. del Rio et al.   SCIENCE

A Delayed Type of Three-Dimensional Growth of Human Endothelial Cells Under Simulated Weightlessness

(2009) Daniela Grimm et al.   TISSUE ENGINEERING PART A

Different Responsiveness of Endothelial Cells to Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor Added to Culture Media Under Gravity and Simulated Microgravity

(2009) Daniela Grimm et al.   TISSUE ENGINEERING PART A

Simulated weightlessness alters biological characteristics of human breast cancer cell line MCF-7

(2008) Airong Qian et al.   ACTA ASTRONAUTICA

Evidence for the Involvement of miRNA in Redox Regulated Angiogenic Response of Human Microvascular Endothelial Cells

(2008) Shani Shilo et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Effects of basic fibroblast growth factor on endothelial cells under conditions of simulated microgravity

(2008) Claudia Ulbrich et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Monolayer and Spheroid Culture of Human Liver Hepatocellular Carcinoma Cell Line Cells Demonstrate Distinct Global Gene Expression Patterns and Functional Phenotypes

(2008) Tammy T. Chang et al.   TISSUE ENGINEERING PART A

Gravitational unloading induces an anti-angiogenic phenotype in human microvascular endothelial cells

(2007) Massimo Mariotti et al.   JOURNAL OF CELLULAR BIOCHEMISTRY