Anticoagulant effects of statins and their clinical implications

Statins as Antithrombotic Drugs

(2013) Francesco Violi et al.   CIRCULATION

Statin treatment and the risk of recurrent pulmonary embolism

(2013) S. Biere-Rafi et al.   EUROPEAN HEART JOURNAL

Statin therapy and levels of hemostatic factors in a healthy population: the Multi-Ethnic Study of Atherosclerosis

(2013) N. B. Adams et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Management of Cardiovascular Risk: The Importance of Meeting Lipid Targets

(2012) Antonio M. Gotto et al.   AMERICAN JOURNAL OF CARDIOLOGY

Effect of shear stress, statins and TNF-α on hemostatic genes in human endothelial cells

(2012) N. Bergh et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Impact of Statins on the Coagulation Status of Type 2 Diabetes Patients Evaluated by a Novel Thrombin-Generation Assay

(2012) P. Ferroni et al.   CARDIOVASCULAR DRUGS AND THERAPY

Monocyte tissue factor–dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin

(2012) A. Phillip Owens et al.   JOURNAL OF CLINICAL INVESTIGATION

Statins but Not Aspirin Reduce Thrombotic Risk Assessed by Thrombin Generation in Diabetic Patients without Cardiovascular Events: The RATIONAL Trial

(2012) Alejandro Macchia et al.   PLoS One

Statin Therapy and the Risk of Intracerebral Hemorrhage

(2012) James S. McKinney et al.   STROKE

Effects of atorvastatin on plasma fibrin clot properties in apparently healthy individuals and patients with previous venous thromboembolism

(2012) Marek Zolcinski et al.   THROMBOSIS AND HAEMOSTASIS

Tissue factor and factor VIIa – Hemostasis and beyond

(2012) Alisa S. Wolberg et al.   THROMBOSIS RESEARCH

Effect of Statins on Venous Thromboembolic Events: A Meta-analysis of Published and Unpublished Evidence from Randomised Controlled Trials

(2012) Kazem Rahimi et al.   PLOS MEDICINE

Thrombin Generation in Hemorrhage Control and Vascular Occlusion

(2011) Kenneth G. Mann   CIRCULATION

Updated evidence on early statin therapy for acute coronary syndromes: Meta-analysis of 18 randomized trials involving over 14,000 patients

(2011) Matthias Briel et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment

(2011) Janet van Kuilenburg et al.   Journal of Clinical Lipidology

Statins prevent tissue factor induction by protease-activated receptors 1 and 2 in human umbilical vein endothelial cells in vitro

(2011) C. BANFI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Atorvastatin reduces thrombin generation and expression of tissue factor, P-selectin and GPIIIa on platelet-derived microparticles in patients with peripheral arterial occlusive disease

(2011) Fariborz Mobarrez et al.   THROMBOSIS AND HAEMOSTASIS

Statins in the prevention of venous thromboembolism: A meta-analysis of observational studies

(2011) Menaka Pai et al.   THROMBOSIS RESEARCH

Statin use in patients with nephrotic syndrome is associated with a lower risk of venous thromboembolism

(2011) Mohammad Resh et al.   THROMBOSIS RESEARCH

Effects of rosuvastatin on vascular biomarkers and carotid atherosclerosis in lupus: A randomized, double-blind, placebo-controlled trial

(2011) Chi Chiu Mok et al.   ARTHRITIS CARE & RESEARCH

Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)

(2011) Dilys J Freeman et al.   BMC Geriatrics

Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials

(2010)   LANCET

Effect of simvastatin on Kruppel-like factor2, endothelial nitric oxide synthase and thrombomodulin expression in endothelial cells under shear stress

(2010) Joanna Rossi et al.   LIFE SCIENCES

Prothrombinase formation at the site of microvascular injury and aspirin resistance: The effect of simvastatin

(2010) Anetta Undas et al.   THROMBOSIS RESEARCH

Statins Decrease the Occurrence of Venous Thromboembolism in Patients with Cancer

(2009) Danai Khemasuwan et al.   AMERICAN JOURNAL OF MEDICINE

Tissue Factor in Coagulation

(2009) Saulius Butenas et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Statins and Cardiovascular Diseases: From Cholesterol Lowering to Pleiotropy

(2009) Qian Zhou et al.   CURRENT PHARMACEUTICAL DESIGN

Statins in Acute Coronary Syndromes

(2009) Ryan P. Morrissey et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The many faces of tissue factor

(2009) N. MACKMAN   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial cardiovascular events, statins, low-dose aspirin and subsequent risk of venous thromboembolism: a population-based case-control study

(2009) H. T. SØRENSEN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism

(2009) Robert J. Glynn et al.   NEW ENGLAND JOURNAL OF MEDICINE

Markers of inflammation, thrombosis and endothelial activation correlate with carotid IMT regression in stable coronary disease after atorvastatin treatment

(2009) D. Baldassarre et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Prior simvastatin treatment is associated with reduced thrombin generation and platelet activation in patients with acute ST-segment elevation myocardial infarction

(2009) Maciej Pastuszczak et al.   THROMBOSIS RESEARCH

Increased expression of C-reactive protein and tissue factor in acute coronary syndrome lesions

(2008) René P. Andrié et al.   ATHEROSCLEROSIS

Tissue factor +5466A>G polymorphism determines thrombin formation following vascular injury and thrombin-lowering effects of simvastatin in patients with ischemic heart disease

(2008) Anetta Undas et al.   ATHEROSCLEROSIS

Advances in understanding pathogenic mechanisms of thrombophilic disorders

(2008) B. Dahlback   BLOOD

Systemic blood coagulation activation in acute coronary syndromes

(2008) A. Undas et al.   BLOOD

Inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase does not inhibit the platelet procoagulant response

(2008) T. LINDHOUT et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

HMG-CoA reductase inhibitors, other lipid-lowering medication, antiplatelet therapy, and the risk of venous thrombosis

(2008) A. S. RAMCHARAN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS