Binding of vitronectin and Factor H to Hic contributes to immune evasion of Streptococcus pneumoniae serotype 3

Distinct localization of the complement C5b-9 complex on Gram-positive bacteria

(2013) Evelien T. M. Berends et al.   CELLULAR MICROBIOLOGY

Molecular architecture ofStreptococcus pneumoniaesurface thioredoxin-fold lipoproteins crucial for extracellular oxidative stress resistance and maintenance of virulence

(2013) Malek Saleh et al.   EMBO Molecular Medicine

The Choline-binding Protein PspC ofStreptococcus pneumoniaeInteracts with the C-terminal Heparin-binding Domain of Vitronectin

(2013) Sylvia Voss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The complement membrane attack complex triggers intracellular Ca2+ fluxes leading to NLRP3 inflammasome activation

(2013) K. Triantafilou et al.   JOURNAL OF CELL SCIENCE

Human complement control and complement evasion by pathogenic microbes – Tipping the balance

(2013) Peter F. Zipfel et al.   MOLECULAR IMMUNOLOGY

Haemophilus influenzaeacquires vitronectin via the ubiquitous Protein F to subvert host innate immunity

(2013) Yu-Ching Su et al.   MOLECULAR MICROBIOLOGY

Dynamics of Streptococcus pneumoniae Serotypes Causing Acute Otitis Media Isolated from Children with Spontaneous Middle-Ear Drainage over a 12-Year Period (1999–2010) in a Region of Northern Spain

(2013) Marta Alonso et al.   PLoS One

Combat Pneumococcal Infections: Adhesins as Candidates for Protein- Based Vaccine Development

(2012) Gustavo Gamez et al.   CURRENT DRUG TARGETS

Streptococcus pneumoniae Capsular Serotype Invasiveness Correlates with the Degree of Factor H Binding and Opsonization with C3b/iC3b

(2012) Catherine Hyams et al.   INFECTION AND IMMUNITY

Heterologous expression of pneumococcal virulence factor PspC on the surface of Lactococcus lactis confers adhesive properties

(2012) T. M. Asmat et al.   MICROBIOLOGY-SGM

Impact of pneumococcal microbial surface components recognizing adhesive matrix molecules on colonization

(2012) S. Voß et al.   Molecular Oral Microbiology

Pathogenesis and Pathophysiology of Pneumococcal Meningitis

(2011) B. B. Mook-Kanamori et al.   CLINICAL MICROBIOLOGY REVIEWS

Serotype 3 is a common serotype causing invasive pneumococcal disease in children less than 5 years old, as identified by real-time PCR

(2011) L. Selva et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Meningococcal surface fibril (Msf) binds to activated vitronectin and inhibits the terminal complement pathway to increase serum resistance

(2011) Natalie J. Griffiths et al.   MOLECULAR MICROBIOLOGY

Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex

(2011) Birendra Singh et al.   MOLECULAR MICROBIOLOGY

Vitronectin in Vascular Context: Facets of a Multitalented Matricellular Protein

(2011) Klaus Preissner et al.   SEMINARS IN THROMBOSIS AND HEMOSTASIS

Complement inhibition by human vitronectin involves non-heparin binding domains

(2010) M. SHEEHAN et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Association of Serotype with Risk of Death Due to Pneumococcal Pneumonia: A Meta‐Analysis

(2010) Daniel M. Weinberger et al.   CLINICAL INFECTIOUS DISEASES

Heparin binding domain in vitronectin is required for oligomerization and thus enhances integrin mediated cell adhesion and spreading

(2010) Chandramouli R Chillakuri et al.   FEBS LETTERS

The Proline-Rich Region of Pneumococcal Surface Proteins A and C Contains Surface-Accessible Epitopes Common to All Pneumococci and Elicits Antibody-Mediated Protection against Sepsis

(2010) C. C. Daniels et al.   INFECTION AND IMMUNITY

Complement Regulator Factor H Mediates a Two-step Uptake ofStreptococcus pneumoniaeby Human Cells

(2010) Vaibhav Agarwal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vitronectin in bacterial pathogenesis: a host protein used in complement escape and cellular invasion

(2010) Birendra Singh et al.   MOLECULAR MICROBIOLOGY

Vitronectin binds to the head region ofMoraxella catarrhalisubiquitous surface protein A2 and confers complement-inhibitory activity

(2010) Birendra Singh et al.   MOLECULAR MICROBIOLOGY

PavB is a surface-exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections

(2010) Inga Jensch et al.   MOLECULAR MICROBIOLOGY

Neisseria meningitidis Opc Invasin Binds to the Sulphated Tyrosines of Activated Vitronectin to Attach to and Invade Human Brain Endothelial Cells

(2010) Claudia Sa E Cunha et al.   PLoS Pathogens

Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells

(2009) S. Bergmann et al.   JOURNAL OF CELL SCIENCE

Laminin receptor initiates bacterial contact with the blood brain barrier in experimental meningitis models

(2009) Carlos J. Orihuela et al.   JOURNAL OF CLINICAL INVESTIGATION

Clinical Isolates of Streptococcus pneumoniae Bind the Complement Inhibitor C4b-Binding Protein in a PspC Allele-Dependent Fashion

(2009) A. Dieudonne-Vatran et al.   JOURNAL OF IMMUNOLOGY

Nontypeable Haemophilus influenzae Protein E Binds Vitronectin and Is Important for Serum Resistance

(2009) T. Hallstrom et al.   JOURNAL OF IMMUNOLOGY

Pneumolysin: A Double-Edged Sword During the Host-Pathogen Interaction

(2008) Helen Marriott et al.   CURRENT MOLECULAR MEDICINE

PfbA, a Novel Plasmin- and Fibronectin-binding Protein ofStreptococcus pneumoniae, Contributes to Fibronectin-dependent Adhesion and Antiphagocytosis

(2008) Masaya Yamaguchi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The complement fitness Factor H: Role in human diseases and for immune escape of pathogens, like pneumococci

(2008) Peter F. Zipfel et al.   VACCINE

Pneumococcal Pili Are Composed of Protofilaments Exposing Adhesive Clusters of Rrg A

(2008) Markus Hilleringmann et al.   PLoS Pathogens