Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes

Amyloid and Alzheimer's Disease: Inside and Out

(2014) Joshua H. K. Tam et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms

(2014) Leslie I. Grad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Amyloid Precursor Protein is rapidly transported from the Golgi apparatus to the lysosome and where it is processed into beta-amyloid

(2014) Joshua HK Tam et al.   Molecular Brain

FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth

(2013) Hei Nga Maggie Cheung et al.   FASEB JOURNAL

Components of the CtBP1/BARS-dependent fission machinery

(2013) Carmen Valente et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D

(2012) Kevin Moreau et al.   JOURNAL OF CELL BIOLOGY

Cross-Linking of Cell Surface Amyloid Precursor Protein Leads to Increased  -Amyloid Peptide Production in Hippocampal Neurons: Implications for Alzheimer's Disease

(2012) R. Lefort et al.   JOURNAL OF NEUROSCIENCE

Notch in the Vertebrate Nervous System: An Old Dog with New Tricks

(2011) Tarran Pierfelice et al.   NEURON

ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1

(2011) R. Sannerud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocytosis unplugged: multiple ways to enter the cell

(2010) Sudha Kumari et al.   CELL RESEARCH

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

(2010) Mirkka Koivusalo et al.   JOURNAL OF CELL BIOLOGY

Rapid and Direct Transport of Cell Surface APP to the Lysosome defines a novel selective pathway

(2010) Angela Lorenzen et al.   Molecular Brain

Amyloid precursor protein and its homologues: a family of proteolysis-dependent receptors

(2009) Kristin T. Jacobsen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Clathrin-independent internalization of normal cellular prion protein in neuroblastoma cells is associated with the Arf6 pathway

(2009) Y.-S. Kang et al.   JOURNAL OF CELL SCIENCE

Nerve growth factor activation of the TrkA receptor induces cell death, by macropinocytosis, in medulloblastoma Daoy cells

(2009) Chunhui Li et al.   JOURNAL OF NEUROCHEMISTRY

Microglia Mediate the Clearance of Soluble A  through Fluid Phase Macropinocytosis

(2009) S. Mandrekar et al.   JOURNAL OF NEUROSCIENCE

Mutations in amyloid precursor protein affect its interactions with presenilin/γ-secretase

(2009) Lauren Herl et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

(2009) X. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining Macropinocytosis

(2009) Markus C. Kerr et al.   TRAFFIC

Clathrin-independent endocytosis: A unique platform for cell signaling and PM remodeling

(2008) J DONALDSON et al.   CELLULAR SIGNALLING

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS

(2008) Prisca Liberali et al.   EMBO JOURNAL

Amyloid Precursor Protein Trafficking, Processing, and Function

(2008) Gopal Thinakaran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a developmentally regulated pathway of membrane retrieval in neuronal growth cones

(2008) D. Bonanomi et al.   JOURNAL OF CELL SCIENCE

Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons

(2008) A. Schneider et al.   JOURNAL OF NEUROSCIENCE

Ca2+ induces macropinocytosis via F-actin depolymerization during growth cone collapse

(2008) Hiroyuki Kabayama et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Specific Biarsenical Labeling of Cell Surface Proteins Allows Fluorescent- and Biotin-tagging of Amyloid Precursor Protein and Prion Proteins

(2008) Yuzuru Taguchi et al.   MOLECULAR BIOLOGY OF THE CELL

Endocytosis Is Required for Synaptic Activity-Dependent Release of Amyloid-β In Vivo

(2008) John R. Cirrito et al.   NEURON